Antagonistic Regulation of Dlx2 Expression by PITX2 and Msx2: Implications for Tooth Development

The transcriptional mechanisms underlying tooth development are only beginning to be understood. Pitx2, a bicoid-like homeodomain transcription factor, is the first transcriptional marker observed during tooth development. Because Pitx2, Msx2, and Dlx2 are expressed in the dental epithelium, we exam...

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Veröffentlicht in:	Gene expression 2001-01, Vol.9 (6), p.265-281
Hauptverfasser:	Green, P D, Hjalt, T A, Kirk, D E, Sutherland, L B, Thomas, B L, Sharpe, P T, Snead, M L, Murray, J C, Russo, A F, Amendt, B A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Blotting, Western CHO Cells Cricetinae Cytoskeletal Proteins Dlx2 gene DNA Probes DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism DNA-Binding Proteins - physiology Drosophila Proteins Electrophoretic Mobility Shift Assay Epithelial Cells - cytology Gene Expression Regulation, Developmental - physiology Homeobox Protein PITX2 Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Homeodomain Proteins - physiology Msx2 protein Nuclear Proteins Pitx2 Dlx2 Transcriptional Regulation Pitx2 gene Promoter Regions, Genetic Protein Binding Reverse Transcriptase Polymerase Chain Reaction RNA-Binding Proteins Tooth - cytology Tooth - growth & development Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors - metabolism Transcription Factors - physiology Transcription, Genetic - physiology
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