Studying of genotoxicity of glyphosate herbicide on mammal cells

Glyphosate herbicide used to control unwanted annual and perennial plants. Roundup, one of the most widely used products containing glyphosate, is classified as hazardous to the environment.  Therefore, this study aim to assess the effect of (25mg/kg) and (50mg/kg) of glyphosate, given to mice by &q...

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Veröffentlicht in:Journal of the College of Basic Education 2023-02, Vol.20 (86), p.1023-1030
Hauptverfasser: مرتضى غافل جاسم, عبد الامير ناصر غلوب, سعد محمد ندا
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container_end_page 1030
container_issue 86
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container_title Journal of the College of Basic Education
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creator مرتضى غافل جاسم
عبد الامير ناصر غلوب
سعد محمد ندا
description Glyphosate herbicide used to control unwanted annual and perennial plants. Roundup, one of the most widely used products containing glyphosate, is classified as hazardous to the environment.  Therefore, this study aim to assess the effect of (25mg/kg) and (50mg/kg) of glyphosate, given to mice by "gavage" and "feeding", by exposure of Cyprinus carpio (Common carp) to the herbicide with the same concentration and then given to mice, and noticeable cytogenetic effects (DNA damage) on mice bone marrow cells (in vivo) by using Comet assay. The statistical analysis shows that glyphosate cause significant increase (P≤0.01) of DNA damage of bone marrow cells in mice in comparing with the negative controls.
doi_str_mv 10.35950/cbej.v20i86.9744
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