Сertain pathomorphological features of isolated sphenoiditis

Purpose: to study the pathomorphological features of various forms of isolated sphenoiditis. Materials and methods: We analyzed the data of surgical biopsy material of 23 patients aged 18 to 68 years who were on inpatient treatment at the Semashko State Medical University (Department of Ear, Throat and Nose Diseases of the Federal State Budgetary Educational Institution "PIMU" of the Ministry of Health of the Russian Federation) in the period 2019-2022. Results: In our study, it was found that in the structure of IS, the most common is the polypous-cystic form of KP lesion, which is diagnosed statistically significantly more often than fungal IS (p=0.001). The results of the pathomorphological study in all our observations showed a picture of a nonspecific chronic inflammatory process. Conclusions: Determining the phenotypes of isolated sphenoiditis is very important for building a consistent treatment strategy, especially against the background of a large number of tactical and diagnostic errors.For more effective and visual performance of such data analysis, we have developed a "Checklist for pathomorphological examination in pathology of the sphenoid sinus".The pathomorphological landscape of lesions of the sphenoid sinus, obtained in our study, generally corresponds to the picture of lesions of other groups of paranasal sinuses.