Kaplı ve Kaplı Olmayan Oksijenatörlerde Kardiopulmoner Sistemlerin Antioksidanlar Üzerine Etkileri

Amaç: Kardiyopulmoner Bypass'ta (KPB) kaplı ve kaplı olmayan sistemlerin antioksidanlar üzerindeki etkilerine ve elde ettiğimiz bilgiler doğrultusunda klinik uygulamalarda olası cerrahi yöntemlere katkı sağlamayı amaçlıyoruz. Yöntem: Açık kalp cerrahisi ameliyatına dahil edilen 15 kaplı ve 15 k...

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Veröffentlicht in:Harran Üniversitesi Tıp Fakültesi Dergisi 2023-04, Vol.20 (1), p.226-231
Hauptverfasser: KORKMAZ ERSÖZ, Ezhar, ANDAÇ, Mehmet Halit, HACANLI, Yasemin, AYDIN, Mehmet Salih, DİKME, Reşat
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creator KORKMAZ ERSÖZ, Ezhar
ANDAÇ, Mehmet Halit
HACANLI, Yasemin
AYDIN, Mehmet Salih
DİKME, Reşat
description Amaç: Kardiyopulmoner Bypass'ta (KPB) kaplı ve kaplı olmayan sistemlerin antioksidanlar üzerindeki etkilerine ve elde ettiğimiz bilgiler doğrultusunda klinik uygulamalarda olası cerrahi yöntemlere katkı sağlamayı amaçlıyoruz. Yöntem: Açık kalp cerrahisi ameliyatına dahil edilen 15 kaplı ve 15 kaplı olmayan oksijenatörden toplam 30 hastadan anestezi, pompa girişi, kros klemp başlangıcı, kros klemp sonu, pompa sonu olmak üzere 5 farklı zamanda alınan kan çalışmaya dahil edildi. Bulgular: Demografik verilere göre çalışmaya dahil edilen kaplı oksijenatörler (grup I) ve kaplı olmayan oksijenatörler (grup II) olarak; 63.3'ü kadın, 36.7'si erkek olmak üzere 30 hastaya işlem uygulandı. Hasta gruplarının klemp süresi, toplam antioksidan kapasite1 ve 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematokrit (Hct) ve trombosit (Plt) değerleri cinsiyete göre gruplar arasında anlamlı farklılık göstermedi (p>0,05) ). Sonuç: Kardiyopulmoner Bypass (KPB) sırasında kaplı ve kaplı olmayan preoperatif, intraoperatif ve postoperatif dönemde Hgb, Hct ve Plt ve TAOK değerlerini etkilemediği sonucuna varıldı. Objective: We aim to contribute to the effects of coated and uncoated systems on antioxidants in Cardiopulmonary Bypass (CPB) and to possible surgical methods in clinical applications in line with the information we have obtained. Material And Method: Blood taken at 5 different times including anesthesia, pump entry, cross-clamp start, cross-clamp end, pump end from a total of 30 patients from 15 coated and 15 non-coated oxygenators included in open heart surgery surgery were included in the study. Result:As coated oxygenators (group I) and uncoated oxygenators (group II) included in the study according to demographic data; Thirty patients, 63.3 female and 36.7 male, underwent the procedure. Cross-clemp duration, total antioxidant capacity1 and 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematocrit (Hct) and platelet (Plt) values of the patient groups according to gender were not significantly different between the groups (p>0.05). Conclusion: It was concluded that coated and uncoated systems during Cardiopulmonary Bypass (CPB) did not affect Hgb, Hct, Plt and TAOK values in the preoperative, intraoperative and postoperative periods. Background: We aim to contribute to the effects of coated and uncoated systems on antioxidants in Cardiopulmonary Bypass (CPB) and to possible surgical methods in clinical applications in line with the information we have obtained. Materials and Methods: Blood
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Yöntem: Açık kalp cerrahisi ameliyatına dahil edilen 15 kaplı ve 15 kaplı olmayan oksijenatörden toplam 30 hastadan anestezi, pompa girişi, kros klemp başlangıcı, kros klemp sonu, pompa sonu olmak üzere 5 farklı zamanda alınan kan çalışmaya dahil edildi. Bulgular: Demografik verilere göre çalışmaya dahil edilen kaplı oksijenatörler (grup I) ve kaplı olmayan oksijenatörler (grup II) olarak; 63.3'ü kadın, 36.7'si erkek olmak üzere 30 hastaya işlem uygulandı. Hasta gruplarının klemp süresi, toplam antioksidan kapasite1 ve 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematokrit (Hct) ve trombosit (Plt) değerleri cinsiyete göre gruplar arasında anlamlı farklılık göstermedi (p&gt;0,05) ). Sonuç: Kardiyopulmoner Bypass (KPB) sırasında kaplı ve kaplı olmayan preoperatif, intraoperatif ve postoperatif dönemde Hgb, Hct ve Plt ve TAOK değerlerini etkilemediği sonucuna varıldı. Objective: We aim to contribute to the effects of coated and uncoated systems on antioxidants in Cardiopulmonary Bypass (CPB) and to possible surgical methods in clinical applications in line with the information we have obtained. Material And Method: Blood taken at 5 different times including anesthesia, pump entry, cross-clamp start, cross-clamp end, pump end from a total of 30 patients from 15 coated and 15 non-coated oxygenators included in open heart surgery surgery were included in the study. Result:As coated oxygenators (group I) and uncoated oxygenators (group II) included in the study according to demographic data; Thirty patients, 63.3 female and 36.7 male, underwent the procedure. Cross-clemp duration, total antioxidant capacity1 and 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematocrit (Hct) and platelet (Plt) values of the patient groups according to gender were not significantly different between the groups (p&gt;0.05). Conclusion: It was concluded that coated and uncoated systems during Cardiopulmonary Bypass (CPB) did not affect Hgb, Hct, Plt and TAOK values in the preoperative, intraoperative and postoperative periods. Background: We aim to contribute to the effects of coated and uncoated systems on antioxidants in Cardiopulmonary Bypass (CPB) and to possible surgical methods in clinical applications in line with the information we have obtained. Materials and Methods: Blood taken at 5 different times including anesthesia, pump entry, cross-clamp start, cross-clamp end, pump end from a total of 30 patients from 15 coated and 15 non-coated oxygenators included in open heart surgery surgery were included in the study. Results: As coated oxygenators (group I) and uncoated oxygenators (group II) included in the study according to demographic data; Thirty patients, 63.3 female and 36.7 male, underwent the procedure. Cross-clemp duration, total antioxidant capacity1 and 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematocrit (Hct) and platelet (Plt) values of the patient groups according to gender were not significantly different between the groups (p&gt;0.05). Conclusions: It was concluded that coated and uncoated systems during Cardiopulmonary Bypass (CPB) did not affect Hgb, Hct, Plt and TAOK values in the preoperative, intraoperative and posto-perative periods.</description><identifier>ISSN: 1304-9623</identifier><identifier>DOI: 10.35440/hutfd.1277248</identifier><language>eng</language><ispartof>Harran Üniversitesi Tıp Fakültesi Dergisi, 2023-04, Vol.20 (1), p.226-231</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-crossref_primary_10_35440_hutfd_12772483</cites><orcidid>0000-0002-8673-8481 ; 0000-0002-4427-8149 ; 0000-0002-6652-6035 ; 0000-0002-7531-4958 ; 0000-0001-9157-7830</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids></links><search><creatorcontrib>KORKMAZ ERSÖZ, Ezhar</creatorcontrib><creatorcontrib>ANDAÇ, Mehmet Halit</creatorcontrib><creatorcontrib>HACANLI, Yasemin</creatorcontrib><creatorcontrib>AYDIN, Mehmet Salih</creatorcontrib><creatorcontrib>DİKME, Reşat</creatorcontrib><title>Kaplı ve Kaplı Olmayan Oksijenatörlerde Kardiopulmoner Sistemlerin Antioksidanlar Üzerine Etkileri</title><title>Harran Üniversitesi Tıp Fakültesi Dergisi</title><description>Amaç: Kardiyopulmoner Bypass'ta (KPB) kaplı ve kaplı olmayan sistemlerin antioksidanlar üzerindeki etkilerine ve elde ettiğimiz bilgiler doğrultusunda klinik uygulamalarda olası cerrahi yöntemlere katkı sağlamayı amaçlıyoruz. Yöntem: Açık kalp cerrahisi ameliyatına dahil edilen 15 kaplı ve 15 kaplı olmayan oksijenatörden toplam 30 hastadan anestezi, pompa girişi, kros klemp başlangıcı, kros klemp sonu, pompa sonu olmak üzere 5 farklı zamanda alınan kan çalışmaya dahil edildi. Bulgular: Demografik verilere göre çalışmaya dahil edilen kaplı oksijenatörler (grup I) ve kaplı olmayan oksijenatörler (grup II) olarak; 63.3'ü kadın, 36.7'si erkek olmak üzere 30 hastaya işlem uygulandı. Hasta gruplarının klemp süresi, toplam antioksidan kapasite1 ve 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematokrit (Hct) ve trombosit (Plt) değerleri cinsiyete göre gruplar arasında anlamlı farklılık göstermedi (p&gt;0,05) ). Sonuç: Kardiyopulmoner Bypass (KPB) sırasında kaplı ve kaplı olmayan preoperatif, intraoperatif ve postoperatif dönemde Hgb, Hct ve Plt ve TAOK değerlerini etkilemediği sonucuna varıldı. Objective: We aim to contribute to the effects of coated and uncoated systems on antioxidants in Cardiopulmonary Bypass (CPB) and to possible surgical methods in clinical applications in line with the information we have obtained. Material And Method: Blood taken at 5 different times including anesthesia, pump entry, cross-clamp start, cross-clamp end, pump end from a total of 30 patients from 15 coated and 15 non-coated oxygenators included in open heart surgery surgery were included in the study. Result:As coated oxygenators (group I) and uncoated oxygenators (group II) included in the study according to demographic data; Thirty patients, 63.3 female and 36.7 male, underwent the procedure. Cross-clemp duration, total antioxidant capacity1 and 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematocrit (Hct) and platelet (Plt) values of the patient groups according to gender were not significantly different between the groups (p&gt;0.05). Conclusion: It was concluded that coated and uncoated systems during Cardiopulmonary Bypass (CPB) did not affect Hgb, Hct, Plt and TAOK values in the preoperative, intraoperative and postoperative periods. Background: We aim to contribute to the effects of coated and uncoated systems on antioxidants in Cardiopulmonary Bypass (CPB) and to possible surgical methods in clinical applications in line with the information we have obtained. Materials and Methods: Blood taken at 5 different times including anesthesia, pump entry, cross-clamp start, cross-clamp end, pump end from a total of 30 patients from 15 coated and 15 non-coated oxygenators included in open heart surgery surgery were included in the study. Results: As coated oxygenators (group I) and uncoated oxygenators (group II) included in the study according to demographic data; Thirty patients, 63.3 female and 36.7 male, underwent the procedure. Cross-clemp duration, total antioxidant capacity1 and 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematocrit (Hct) and platelet (Plt) values of the patient groups according to gender were not significantly different between the groups (p&gt;0.05). Conclusions: It was concluded that coated and uncoated systems during Cardiopulmonary Bypass (CPB) did not affect Hgb, Hct, Plt and TAOK values in the preoperative, intraoperative and posto-perative periods.</description><issn>1304-9623</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqVjz0OgjAcxTtoIlFW514ALLSKjsZoTBwYdG-qlFgthfxbTfQsXsLFC-DBFMMFnN7L-xh-CA0jEtIxY2R0vLg8C6M4SWI27SAvooQFs0lMe8i3Vu0JYwmdUko8lG9Epd9PfJW4dakuxE0YnJ6tOkkjXP0CLSFrBpCpsrroojQS8FZZJ4tvpQyeG6fK7yETRgvA9ePexBIv3Vk1iwHq5kJb6bfaR-FquVusgwOU1oLMeQWqEHDjEeE_CP6D4C0E_fvwAX1YV6I</recordid><startdate>20230427</startdate><enddate>20230427</enddate><creator>KORKMAZ ERSÖZ, Ezhar</creator><creator>ANDAÇ, Mehmet Halit</creator><creator>HACANLI, Yasemin</creator><creator>AYDIN, Mehmet Salih</creator><creator>DİKME, Reşat</creator><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0002-8673-8481</orcidid><orcidid>https://orcid.org/0000-0002-4427-8149</orcidid><orcidid>https://orcid.org/0000-0002-6652-6035</orcidid><orcidid>https://orcid.org/0000-0002-7531-4958</orcidid><orcidid>https://orcid.org/0000-0001-9157-7830</orcidid></search><sort><creationdate>20230427</creationdate><title>Kaplı ve Kaplı Olmayan Oksijenatörlerde Kardiopulmoner Sistemlerin Antioksidanlar Üzerine Etkileri</title><author>KORKMAZ ERSÖZ, Ezhar ; ANDAÇ, Mehmet Halit ; HACANLI, Yasemin ; AYDIN, Mehmet Salih ; DİKME, Reşat</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-crossref_primary_10_35440_hutfd_12772483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KORKMAZ ERSÖZ, Ezhar</creatorcontrib><creatorcontrib>ANDAÇ, Mehmet Halit</creatorcontrib><creatorcontrib>HACANLI, Yasemin</creatorcontrib><creatorcontrib>AYDIN, Mehmet Salih</creatorcontrib><creatorcontrib>DİKME, Reşat</creatorcontrib><collection>CrossRef</collection><jtitle>Harran Üniversitesi Tıp Fakültesi Dergisi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KORKMAZ ERSÖZ, Ezhar</au><au>ANDAÇ, Mehmet Halit</au><au>HACANLI, Yasemin</au><au>AYDIN, Mehmet Salih</au><au>DİKME, Reşat</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Kaplı ve Kaplı Olmayan Oksijenatörlerde Kardiopulmoner Sistemlerin Antioksidanlar Üzerine Etkileri</atitle><jtitle>Harran Üniversitesi Tıp Fakültesi Dergisi</jtitle><date>2023-04-27</date><risdate>2023</risdate><volume>20</volume><issue>1</issue><spage>226</spage><epage>231</epage><pages>226-231</pages><issn>1304-9623</issn><abstract>Amaç: Kardiyopulmoner Bypass'ta (KPB) kaplı ve kaplı olmayan sistemlerin antioksidanlar üzerindeki etkilerine ve elde ettiğimiz bilgiler doğrultusunda klinik uygulamalarda olası cerrahi yöntemlere katkı sağlamayı amaçlıyoruz. Yöntem: Açık kalp cerrahisi ameliyatına dahil edilen 15 kaplı ve 15 kaplı olmayan oksijenatörden toplam 30 hastadan anestezi, pompa girişi, kros klemp başlangıcı, kros klemp sonu, pompa sonu olmak üzere 5 farklı zamanda alınan kan çalışmaya dahil edildi. Bulgular: Demografik verilere göre çalışmaya dahil edilen kaplı oksijenatörler (grup I) ve kaplı olmayan oksijenatörler (grup II) olarak; 63.3'ü kadın, 36.7'si erkek olmak üzere 30 hastaya işlem uygulandı. Hasta gruplarının klemp süresi, toplam antioksidan kapasite1 ve 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematokrit (Hct) ve trombosit (Plt) değerleri cinsiyete göre gruplar arasında anlamlı farklılık göstermedi (p&gt;0,05) ). Sonuç: Kardiyopulmoner Bypass (KPB) sırasında kaplı ve kaplı olmayan preoperatif, intraoperatif ve postoperatif dönemde Hgb, Hct ve Plt ve TAOK değerlerini etkilemediği sonucuna varıldı. Objective: We aim to contribute to the effects of coated and uncoated systems on antioxidants in Cardiopulmonary Bypass (CPB) and to possible surgical methods in clinical applications in line with the information we have obtained. Material And Method: Blood taken at 5 different times including anesthesia, pump entry, cross-clamp start, cross-clamp end, pump end from a total of 30 patients from 15 coated and 15 non-coated oxygenators included in open heart surgery surgery were included in the study. Result:As coated oxygenators (group I) and uncoated oxygenators (group II) included in the study according to demographic data; Thirty patients, 63.3 female and 36.7 male, underwent the procedure. Cross-clemp duration, total antioxidant capacity1 and 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematocrit (Hct) and platelet (Plt) values of the patient groups according to gender were not significantly different between the groups (p&gt;0.05). Conclusion: It was concluded that coated and uncoated systems during Cardiopulmonary Bypass (CPB) did not affect Hgb, Hct, Plt and TAOK values in the preoperative, intraoperative and postoperative periods. Background: We aim to contribute to the effects of coated and uncoated systems on antioxidants in Cardiopulmonary Bypass (CPB) and to possible surgical methods in clinical applications in line with the information we have obtained. Materials and Methods: Blood taken at 5 different times including anesthesia, pump entry, cross-clamp start, cross-clamp end, pump end from a total of 30 patients from 15 coated and 15 non-coated oxygenators included in open heart surgery surgery were included in the study. Results: As coated oxygenators (group I) and uncoated oxygenators (group II) included in the study according to demographic data; Thirty patients, 63.3 female and 36.7 male, underwent the procedure. Cross-clemp duration, total antioxidant capacity1 and 3 (TAOK1, TAOK 3), hemoglobin (Hgb), hematocrit (Hct) and platelet (Plt) values of the patient groups according to gender were not significantly different between the groups (p&gt;0.05). Conclusions: It was concluded that coated and uncoated systems during Cardiopulmonary Bypass (CPB) did not affect Hgb, Hct, Plt and TAOK values in the preoperative, intraoperative and posto-perative periods.</abstract><doi>10.35440/hutfd.1277248</doi><orcidid>https://orcid.org/0000-0002-8673-8481</orcidid><orcidid>https://orcid.org/0000-0002-4427-8149</orcidid><orcidid>https://orcid.org/0000-0002-6652-6035</orcidid><orcidid>https://orcid.org/0000-0002-7531-4958</orcidid><orcidid>https://orcid.org/0000-0001-9157-7830</orcidid></addata></record>
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title Kaplı ve Kaplı Olmayan Oksijenatörlerde Kardiopulmoner Sistemlerin Antioksidanlar Üzerine Etkileri
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