Familial Mediterranean fever in two brothers aged seven and five years old

Familial Mediterranean fever (FMF) is an inherited disease characterized by fever and intermittent abdominal pain. Due to amyloid deposits in the kidneys and gastrointestinal tract, untreated FMF can lead to severe complications such as end-stage renal disease and malabsorption. The present study reports two brothers aged seven and five years, who presented with fever, abdominal pain, and anorexia. Based on their clinical history and ruling out other possible diagnoses, FMF was definitively diagnosed, and both patients underwent colchicine treatment.