Prediction of Disease-associated Single Nucleotide Polymorphisms Using Virtual Genomes Constructed from a Public Haplotype Database

Objectives: Simultaneous dealing of hundreds of thousands of single nucleotide polymorphisms (SNPs) in genome-wide association studies is laborious. The aim of our study is to develop a method to decrease the number of candidate SNPs prior to the genotyping of study subjects. Methods: We created vir...

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Veröffentlicht in:	Methods of information in medicine 2008-01, Vol.47 (6), p.522-528
Hauptverfasser:	Toyabe, S., Miyashita, A., Kitamura, N., Kuwano, R., Akazawa, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Case-Control Studies Data Collection Genome, Human Genotype genotypes Haplotypes Humans Original Article Pilot Projects Polymorphism, Single Nucleotide Program Development single nucleotide polymorphism Time Factors User-Computer Interface
Online-Zugang:	Volltext
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