Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity

Stroke is a major cause of brain injury in Alaska. Since antioxidant levels are decreased in aged brain, the greater predisposition to neuronal death in stroke leading to subsequent neurodegeneration in aged individuals may be related to changes in oxidant balance. We studied the effect of the endog...

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Veröffentlicht in:	International Journal of Circumpolar Health 2002-02, Vol.61 (1), p.32
Hauptverfasser:	Clapp-Lilly, Kimberly L, Smith, Mark A, Perry, George, Harris, Peggy L, Zhu, Xiongwei, Drew, Kelly L, Duffy, Lawrence K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Brain - drug effects Brain - physiology Brain - physiopathology Excitatory Amino Acid Antagonists - toxicity In Vitro Techniques Melatonin - pharmacology Mice N-Methylaspartate - toxicity Stroke - physiopathology
Online-Zugang:	Volltext
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