Viral Transcript and Tumor Immune Microenvironment-Based Transcriptomic Profiling of HPV-Associated Head and Neck Squamous Cell Carcinoma Identifies Subtypes Associated with Prognosis

Human papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HPV-positive HNSCC) has distinct biological characteristics from HPV-negative HNSCC. Using an AI-based analytical platform on meta cohorts, we profiled expression patterns of viral transcripts and HPV viral genome integrati...

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Veröffentlicht in:Viruses 2024-12, Vol.17 (1), p.4
Hauptverfasser: Nikitina, Anastasiia, Kiriy, Daria, Tyshevich, Andrey, Tychinin, Dmitry, Antysheva, Zoya, Sobol, Anastasya, Kushnarev, Vladimir, Shin, Nara, Brown, Jessica H., Lewis, James, Lang Kuhs, Krystle A., Ferris, Robert, Wirth, Lori, Kotlov, Nikita, Faden, Daniel L.
Format: Artikel
Sprache:eng
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