Suaeda vermiculata Aqueous-Ethanolic Extract-Based Mitigation of CCl4-Induced Hepatotoxicity in Rats, and HepG-2 and HepG-2/ADR Cell-Lines-Based Cytotoxicity Evaluations

Suaeda vermiculata, an edible halophytic plant, used by desert nomads to treat jaundice, was investigated for its hepatoprotective bioactivity and safety profile on its mother liquor aqueous-ethanolic extract. Upon LC-MS (Liquid Chromatography-Mass Spectrometry) analysis, the presence of several con...

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Veröffentlicht in:	Plants (Basel) 2020-09, Vol.9 (10), p.1291
Hauptverfasser:	Mohammed, Salman A. A., Khan, Riaz A., El-Readi, Mahmoud Z., Emwas, Abdul-Hamid, Sioud, Salim, Poulson, Benjamin G., Jaremko, Mariusz, Eldeeb, Hussein M., Al-Omar, Mohsen S., Mohammed, Hamdoon A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute toxicity Alanine Alanine transaminase antioxidant Antioxidants aqueous-ethanolic extract Aspartate transaminase Biocompatibility Biological activity Biomarkers Carbon tetrachloride Cytotoxicity Desert plants Doxorubicin Enzymes Flavonoids halophyte Hepatitis Hepatotoxicity Herbal medicine Investigations Jaundice Kaempferol Kidneys Liquid chromatography Liver diseases liver toxicity Mass spectrometry Mass spectroscopy Metabolism Metabolites Methylcellulose Mode of action Natural products Oxidative stress Plant extracts Quercetin Safety Salinity Scavenging Serum levels Silymarin Suaeda Suaeda vermiculata Sulfonic acid Toxicity testing Transaminase
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