Supramolecular Aggregation Processes on Carbon Surfaces Occurring in Bovine Serum Albumin Solutions

The processes of supramolecular aggregation occurring on carbon surfaces in aqueous solutions of bovine serum albumin (BSA) during drying were studied using modern scanning electron microscopy (SEM). The carbon materials studied were highly oriented pyrolytic graphite (HOPG) and glassy carbon (GC)....

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Veröffentlicht in:Micro 2022-12, Vol.2 (4), p.670-678
Hauptverfasser: Salanov, Aleksei, Serkova, Alexandra, Zhirnova, Anastasia, Perminova, Larisa, Kovalenko, Galina
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container_issue 4
container_start_page 670
container_title Micro
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creator Salanov, Aleksei
Serkova, Alexandra
Zhirnova, Anastasia
Perminova, Larisa
Kovalenko, Galina
description The processes of supramolecular aggregation occurring on carbon surfaces in aqueous solutions of bovine serum albumin (BSA) during drying were studied using modern scanning electron microscopy (SEM). The carbon materials studied were highly oriented pyrolytic graphite (HOPG) and glassy carbon (GC). Based on the analysis of SEM images and EDX-scanning element distribution maps, a possible mechanism for the formation of the observed intricate structures on the surface was proposed. The formation of fuzzy lacy structures resembling shadow replicas was explained by relatively strong hydrophobic–hydrophobic interactions of albumin molecules with carbon surfaces.
doi_str_mv 10.3390/micro2040045
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