Persistent Ependymal Tumor Arising from an Immature Ovarian Teratoma: A Rare Case

Primary ovarian ependymoma is a rare neuroectodermal neoplasm that can arise from immature ovarian teratoma. Due to the paucity of this entity, a complete molecular analysis of these tumors has not been done, thus creating a challenge for finding an effective and safe therapeutic treatment. In the l...

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Veröffentlicht in:Journal of Molecular Pathology 2020-12, Vol.1 (1), p.32-35
Hauptverfasser: Afzal, Anoshia, Lu, Rufei, Asadbeigi, Sepideh N., Fung, Kar-Ming, Peterson, Jo Elle G.
Format: Artikel
Sprache:eng
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Zusammenfassung:Primary ovarian ependymoma is a rare neuroectodermal neoplasm that can arise from immature ovarian teratoma. Due to the paucity of this entity, a complete molecular analysis of these tumors has not been done, thus creating a challenge for finding an effective and safe therapeutic treatment. In the limited literature, patients with primary ovarian ependymoma showed various responses to an array of individualized therapies, ranging from surgeries to chemotherapies. Here, we present a 38-year-old female with persistent ovarian ependymoma, with a molecular profile similar to traditional central nervous system ependymoma that is irresponsive to multiple cytoreduction and clinical experimental therapies. Therefore, a prompt recognition and reporting of this entity can greatly aid in expanding the understanding and standardization of therapies for this neoplasm.
ISSN:2673-5261
2673-5261
DOI:10.3390/jmp1010005