Mitochondrial Function in Modulating Human Granulosa Cell Steroidogenesis and Female Fertility

Ovarian follicle steroidogenesis associated with embryo quality results in a successful pregnancy. Each follicle consists of an oocyte surrounded by granulosa cells, which secrete several steroid and peptide hormones. Follicles harvested from women who conceived after assisted reproductive therapy (...

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Veröffentlicht in:	International journal of molecular sciences 2020-05, Vol.21 (10), p.3592
Hauptverfasser:	Sreerangaraja Urs, Dilip Bhargava, Wu, Wen-Han, Komrskova, Katerina, Postlerova, Pavla, Lin, Yung-Feng, Tzeng, Chii-Ruey, Kao, Shu-Huei
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Acridine orange Adult Annexin V Apoptosis Biosynthesis Correlation Cumulus Cells - metabolism Cysts Cysts - pathology Data analysis Embryos Endometriosis Endometriosis - blood Endometriosis - complications Endometriosis - pathology estradiol Estradiol - blood Female Fertility Fertilization Fertilization in Vitro fertilization rate Flow cytometry Follicles Follicular Fluid - metabolism Gametocytes Granulosa cells Granulosa Cells - metabolism Humans In vitro fertilization Infertility Infertility, Female - blood Infertility, Female - pathology Membrane potential Membranes Mitochondria Mitochondria - metabolism Mitochondrial DNA mitochondrial mass Models, Biological Mutation Oocytes - metabolism Patients Peptide hormones Polycystic ovary syndrome Polycystic Ovary Syndrome - blood Polycystic Ovary Syndrome - complications Polycystic Ovary Syndrome - pathology Pregnancy Pregnancy Outcome progesterone Progesterone - blood Proteins Radioimmunoassay Reproduction Reproductive technologies Sperm Steroid hormones Steroidogenesis Steroidogenic acute regulatory protein Steroids Steroids - biosynthesis Transfection Womens health
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