CHFR and Paclitaxel Sensitivity of Ovarian Cancer

Simple Summary Studies in tissue culture cell lines have indicated that silencing of the mitotic regulator CHFR is associated with increased paclitaxel sensitivity. More recently, it has been suggested that a UBC13-DNMT1-CHFR pathway also modulates sensitivity of ovarian cancer to paclitaxel in the...

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Veröffentlicht in:	Cancers 2021-11, Vol.13 (23), p.6043, Article 6043
Hauptverfasser:	Wahner Hendrickson, Andrea E., Visscher, Daniel W., Hou, Xiaonan, Goergen, Krista M., Atkinson, Hunter J., Beito, Thomas G., Negron, Vivian, Lingle, Wilma L., Bruzek, Amy K., Hurley, Rachel M., Wagner, Jill M., Flatten, Karen S., Peterson, Kevin L., Schneider, Paula A., Larson, Melissa C., Maurer, Matthew J., Kalli, Kimberly R., Oberg, Ann L., Weroha, S. John, Kaufmann, Scott H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Cell culture Cell cycle Chemotherapy Colorectal cancer DNMT1 protein Immunohistochemistry Kinases Life Sciences & Biomedicine Medical prognosis Monoclonal antibodies Oncology Ovarian cancer Ovarian carcinoma Paclitaxel Patients Platinum Poly(ADP-ribose) Proteins Ribose Science & Technology Surgery Taxanes Tissue culture Tumors Xenografts
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