p62-Induced Cancer-Associated Fibroblast Activation via the Nrf2-ATF6 Pathway Promotes Lung Tumorigenesis

Simple Summary Cancer-associated fibroblasts (CAF) arise from normal fibroblasts within the tumor microenvironment (TME) and promote tumorigenesis through metabolic reprograming and secretion of tumor promoting molecules such as transforming growth factor beta (TGF beta). Here, we show that autophag...

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Veröffentlicht in:	Cancers 2021-02, Vol.13 (4), p.864, Article 864
Hauptverfasser:	Kang, Ji In, Kim, Dong Hyun, Sung, Ki Woon, Shim, Sang Mi, Cha-Molstad, Hyunjoo, Soung, Nak Kyun, Lee, Kyung Ho, Hwang, Joonsung, Lee, Hee Gu, Kwon, Yong Tae, Kim, Bo Yeon
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences & Biomedicine Oncology Science & Technology
Online-Zugang:	Volltext
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