Long Noncoding RNA DANCR Activates Wnt/beta-Catenin Signaling through MiR-216a Inhibition in Non-Small Cell Lung Cancer

Long noncoding RNA differentiation antagonizing nonprotein coding RNA (lncRNA-DANCR) is associated with poor prognosis in multiple cancers, and promotes cancer stemness and invasion. However, the exact mechanisms by which DANCR promotes non-small cell lung cancer (NSCLC) remain elusive. In this stud...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomolecules (Basel, Switzerland) Switzerland), 2020-12, Vol.10 (12), p.1646, Article 1646
Hauptverfasser:	Yu, Justine E., Ju, Julia A., Musacchio, Nicholas, Mathias, Trevor J., Vitolo, Michele I.
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Apoptosis - genetics Axin Protein - genetics Axin Protein - metabolism beta Catenin - genetics beta Catenin - metabolism Biochemistry & Molecular Biology c-Myc protein Cell differentiation Cell growth Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Epithelial Cells - metabolism Epithelial Cells - pathology Gene expression Gene Expression Regulation, Neoplastic Genomes Humans Kinases Life Sciences & Biomedicine lncRNA Lung cancer Metastasis microRNA MicroRNAs - antagonists & inhibitors MicroRNAs - genetics MicroRNAs - metabolism miRNA Myc protein non-small cell lung cancer Non-small cell lung carcinoma Proteins Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism RNA, Long Noncoding - antagonists & inhibitors RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Science & Technology Signal transduction Small cell lung carcinoma SOXB1 Transcription Factors - genetics SOXB1 Transcription Factors - metabolism Spheroids, Cellular - metabolism Spheroids, Cellular - pathology Stem cells Tumor suppressor genes Tumorigenesis Wnt Wnt protein Wnt Signaling Pathway - genetics β-Catenin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!