Inactivation of Gi proteins by pertussis toxin diminishes the effectiveness of adrenergic stimuli in conduit arteries from spontaneously hypertensive rats

Treatment with pertussis toxin (PTX) which eliminates the activity of Gi proteins effectively reduces blood pressure (BP) and vascular resistance in spontaneously hypertensive rats (SHR). In this study we have compared the functional characteristics of isolated arteries from SHR with and without PTX...

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Veröffentlicht in:Physiological research 2008, p.299-302
Hauptverfasser: Zemančíková, A, Török, J, Zicha, J, Kuneš, J
Format: Artikel
Sprache:eng
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