Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients

Background: Relation between diabetes mellitus and ischemic heart disease is well established. But the effect of HbA1C on severity of coronary artery disease remains uncertain in non-ST elevation myocardial infarction and diabetic patient. Objective of our study was to know the relationship of HbA1C...

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Veröffentlicht in:Cardiovascular journal 2015-08, Vol.8 (1), p.43-48
Hauptverfasser: Salim, Mahmod Mohammad, Nesa, Malik Fazila Tun, Arif, Rahman Mohammad, Delwar, Hossain Mohammad, Masum, Mandal Md Raihan
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container_end_page 48
container_issue 1
container_start_page 43
container_title Cardiovascular journal
container_volume 8
creator Salim, Mahmod Mohammad
Nesa, Malik Fazila Tun
Arif, Rahman Mohammad
Delwar, Hossain Mohammad
Masum, Mandal Md Raihan
description Background: Relation between diabetes mellitus and ischemic heart disease is well established. But the effect of HbA1C on severity of coronary artery disease remains uncertain in non-ST elevation myocardial infarction and diabetic patient. Objective of our study was to know the relationship of HbA1C with the severity of coronary artery disease.Methods: In this cross sectional analytical study a total of 104 NSTEMI diabetic patients were enrolled by purposive sampling. They were divided into two groups according to the level of HbA1C, Group-I patients having HbA1C7%. Vessel score and Gensini score was calculated from coronary angiogram and compared between groups.Results: Single vessel disease were significantly higher in group-I compared to Group-II( 38.5% vs 7.7% in Group-I vs Group-II,p0.05). Triple vessel disease were significantly higher in group-II compared to Group- I (19.2% vs 44.4% in Group-I vs Group-II,p
doi_str_mv 10.3329/cardio.v8i1.24767
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But the effect of HbA1C on severity of coronary artery disease remains uncertain in non-ST elevation myocardial infarction and diabetic patient. Objective of our study was to know the relationship of HbA1C with the severity of coronary artery disease.Methods: In this cross sectional analytical study a total of 104 NSTEMI diabetic patients were enrolled by purposive sampling. They were divided into two groups according to the level of HbA1C, Group-I patients having HbA1C<7% and Group-II patients having HbA1C >7%. Vessel score and Gensini score was calculated from coronary angiogram and compared between groups.Results: Single vessel disease were significantly higher in group-I compared to Group-II( 38.5% vs 7.7% in Group-I vs Group-II,p<0.05). Double vessel disease were higher in group-II compared to Group-I but the difference was statistically not significant (42.3% vs 48.1% in Group-I vs Group-II respectively (p>0.05). Triple vessel disease were significantly higher in group-II compared to Group- I (19.2% vs 44.4% in Group-I vs Group-II,p<0.05). Mean Vessel score was higher in Group-II compared to Group-I(1.73 ± 0.86 vs 2.50 ±0.70 in Group-I vs Group-II, p<0.05). Mean Gensini score was higher in Group-II compared to Group-I (44.6 ± 38.4 vs 76.9 ± 44.6 in Group-I vs Group-II, p<0.05). There were significant positive linear correlation between HbA1C and Vessels score and Gensini score (p<0.05).Conclusion: This study may be concluded that the presence of HbA1C >7% are associated with of severe coronary artery disease in NSTEMI with diabetes mellitus.Cardiovasc. j. 2015; 8(1): 43-48]]></description><identifier>ISSN: 2071-0917</identifier><identifier>EISSN: 2309-6357</identifier><identifier>DOI: 10.3329/cardio.v8i1.24767</identifier><language>eng</language><ispartof>Cardiovascular journal, 2015-08, Vol.8 (1), p.43-48</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c907-93fbdf818c52cd1b66f521706f54599a4d0e31b6e41a938bc8abcf8fc4ed799a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4125,27924,27925</link.rule.ids></links><search><creatorcontrib>Salim, Mahmod Mohammad</creatorcontrib><creatorcontrib>Nesa, Malik Fazila Tun</creatorcontrib><creatorcontrib>Arif, Rahman Mohammad</creatorcontrib><creatorcontrib>Delwar, Hossain Mohammad</creatorcontrib><creatorcontrib>Masum, Mandal Md Raihan</creatorcontrib><title>Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients</title><title>Cardiovascular journal</title><description><![CDATA[Background: Relation between diabetes mellitus and ischemic heart disease is well established. But the effect of HbA1C on severity of coronary artery disease remains uncertain in non-ST elevation myocardial infarction and diabetic patient. Objective of our study was to know the relationship of HbA1C with the severity of coronary artery disease.Methods: In this cross sectional analytical study a total of 104 NSTEMI diabetic patients were enrolled by purposive sampling. They were divided into two groups according to the level of HbA1C, Group-I patients having HbA1C<7% and Group-II patients having HbA1C >7%. Vessel score and Gensini score was calculated from coronary angiogram and compared between groups.Results: Single vessel disease were significantly higher in group-I compared to Group-II( 38.5% vs 7.7% in Group-I vs Group-II,p<0.05). Double vessel disease were higher in group-II compared to Group-I but the difference was statistically not significant (42.3% vs 48.1% in Group-I vs Group-II respectively (p>0.05). Triple vessel disease were significantly higher in group-II compared to Group- I (19.2% vs 44.4% in Group-I vs Group-II,p<0.05). Mean Vessel score was higher in Group-II compared to Group-I(1.73 ± 0.86 vs 2.50 ±0.70 in Group-I vs Group-II, p<0.05). Mean Gensini score was higher in Group-II compared to Group-I (44.6 ± 38.4 vs 76.9 ± 44.6 in Group-I vs Group-II, p<0.05). There were significant positive linear correlation between HbA1C and Vessels score and Gensini score (p<0.05).Conclusion: This study may be concluded that the presence of HbA1C >7% are associated with of severe coronary artery disease in NSTEMI with diabetes mellitus.Cardiovasc. j. 2015; 8(1): 43-48]]></description><issn>2071-0917</issn><issn>2309-6357</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNotkMtOwzAQRS0EElXpB7DzD6TYsRPHyyiUtlJ5SO0-cpwxNUpjZFtF-XtcymzuzB3NQwehR0qWjOXySSvfW7c8V5Yucy5KcYNmOSMyK1khblNOBM2IpOIeLUL4IimYlIzzGTrXIThtVbRuxM7g9TBpF6ZBRejxRsHJfQ6usyPewRkG_GPjEccj4H0qvY3TZaZx3o3KT7j2EZI82wAqAE5Tb_vD6nWbHNVBtBp_pEMwxvCA7owaAiz-dY4OL6tDs8l27-ttU-8yLYnIJDNdbypa6SLXPe3K0hQ5FSQJL6RUvCfAkg2cKsmqTleq06YymkMvUp_NEb2u1d6F4MG0396e0qstJe0FXXtF117QtX_o2C-cSWYY</recordid><startdate>20150828</startdate><enddate>20150828</enddate><creator>Salim, Mahmod Mohammad</creator><creator>Nesa, Malik Fazila Tun</creator><creator>Arif, Rahman Mohammad</creator><creator>Delwar, Hossain Mohammad</creator><creator>Masum, Mandal Md Raihan</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20150828</creationdate><title>Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients</title><author>Salim, Mahmod Mohammad ; Nesa, Malik Fazila Tun ; Arif, Rahman Mohammad ; Delwar, Hossain Mohammad ; Masum, Mandal Md Raihan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c907-93fbdf818c52cd1b66f521706f54599a4d0e31b6e41a938bc8abcf8fc4ed799a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Salim, Mahmod Mohammad</creatorcontrib><creatorcontrib>Nesa, Malik Fazila Tun</creatorcontrib><creatorcontrib>Arif, Rahman Mohammad</creatorcontrib><creatorcontrib>Delwar, Hossain Mohammad</creatorcontrib><creatorcontrib>Masum, Mandal Md Raihan</creatorcontrib><collection>CrossRef</collection><jtitle>Cardiovascular journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Salim, Mahmod Mohammad</au><au>Nesa, Malik Fazila Tun</au><au>Arif, Rahman Mohammad</au><au>Delwar, Hossain Mohammad</au><au>Masum, Mandal Md Raihan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients</atitle><jtitle>Cardiovascular journal</jtitle><date>2015-08-28</date><risdate>2015</risdate><volume>8</volume><issue>1</issue><spage>43</spage><epage>48</epage><pages>43-48</pages><issn>2071-0917</issn><eissn>2309-6357</eissn><abstract><![CDATA[Background: Relation between diabetes mellitus and ischemic heart disease is well established. But the effect of HbA1C on severity of coronary artery disease remains uncertain in non-ST elevation myocardial infarction and diabetic patient. Objective of our study was to know the relationship of HbA1C with the severity of coronary artery disease.Methods: In this cross sectional analytical study a total of 104 NSTEMI diabetic patients were enrolled by purposive sampling. They were divided into two groups according to the level of HbA1C, Group-I patients having HbA1C<7% and Group-II patients having HbA1C >7%. Vessel score and Gensini score was calculated from coronary angiogram and compared between groups.Results: Single vessel disease were significantly higher in group-I compared to Group-II( 38.5% vs 7.7% in Group-I vs Group-II,p<0.05). Double vessel disease were higher in group-II compared to Group-I but the difference was statistically not significant (42.3% vs 48.1% in Group-I vs Group-II respectively (p>0.05). Triple vessel disease were significantly higher in group-II compared to Group- I (19.2% vs 44.4% in Group-I vs Group-II,p<0.05). Mean Vessel score was higher in Group-II compared to Group-I(1.73 ± 0.86 vs 2.50 ±0.70 in Group-I vs Group-II, p<0.05). Mean Gensini score was higher in Group-II compared to Group-I (44.6 ± 38.4 vs 76.9 ± 44.6 in Group-I vs Group-II, p<0.05). There were significant positive linear correlation between HbA1C and Vessels score and Gensini score (p<0.05).Conclusion: This study may be concluded that the presence of HbA1C >7% are associated with of severe coronary artery disease in NSTEMI with diabetes mellitus.Cardiovasc. j. 2015; 8(1): 43-48]]></abstract><doi>10.3329/cardio.v8i1.24767</doi><tpages>6</tpages></addata></record>
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title Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients
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