Low Serum Folate Level and Increased Risk of Invasive Cervical Cancer in Bangladeshi Women

Low Serum Folate Level and Increased Risk of Invasive Cervical Cancer in Bangladeshi Women

Objective(s): The aim of this study was to evaluate the risk of cervical cancer in relation to serum concentrations of folate.Materials and methods: This case-control study was conducted in the Gynaecologic Oncology Division of Bangabandhu Sheikh Mujib Medical University from November 2015-October 2...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bangladesh journal of obstetrics & gynaecology 2017-10, Vol.31 (1), p.23-27
Hauptverfasser: Ferdous, Jannatul, Khatun, Sabera, Biswas, Subrata Kumar, Pervin, Shahana, Akter, Latifa, Keya, Kashfia Ahmed, Joarder, Mita, Khan, Jawad Mahruj
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 27
container_issue 1
container_start_page 23
container_title Bangladesh journal of obstetrics & gynaecology
container_volume 31
creator Ferdous, Jannatul
Khatun, Sabera
Biswas, Subrata Kumar
Pervin, Shahana
Akter, Latifa
Keya, Kashfia Ahmed
Joarder, Mita
Khan, Jawad Mahruj
description Objective(s): The aim of this study was to evaluate the risk of cervical cancer in relation to serum concentrations of folate.Materials and methods: This case-control study was conducted in the Gynaecologic Oncology Division of Bangabandhu Sheikh Mujib Medical University from November 2015-October 2016. For this study 50 patients with invasive cervical cancer were taken as study population and 50 healthy women of VIA or paps negative were taken as control to observe and compare serum folate level. Exclusion criteria were women with conditions associated with low folate level. Outcome variable was serum folate level and a p value of < 0.05 was considered as significant.Results: Most of the participants belonged to age group 35 to 55 years in both the groups. Most of the study cases had low income status than the control group. Maximum patients with cervical cancer took OCP in comparison to control. Majority of the patients with cervical cancer had significantly low level of serum folate (
doi_str_mv 10.3329/bjog.v31i1.34272
format Article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_3329_bjog_v31i1_34272</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_3329_bjog_v31i1_34272</sourcerecordid><originalsourceid>FETCH-LOGICAL-c158t-fe83045d6303b58de769a9c8802d3732f63517f8f86947419fbc4fc3e6b62dd83</originalsourceid><addsrcrecordid>eNot0F9LwzAUBfAgCo65dx_zBTqT3DRNH7U4HRQE_yD4UtLkZmZ2rSSz4re3m96XAxfOefgRcsnZEkCUV-122CxH4IEvQYpCnJCZkExnWjJ5SmaccZ1JoYtzskhpy6abWiDVjLzVwzd9wvi1o6uhM3ukNY7YUdM7uu5tRJPQ0ceQPujgp89oUhiRVhjHYE1HK9NbjDT09Mb0m844TO-Bvg477C_ImTddwsV_zsnL6va5us_qh7t1dV1nlud6n3nUwGTuFDBoc-2wUKUprdZMOChAeAU5L7z2WpWykLz0rZXeAqpWCec0zAn727VxSCmibz5j2Jn403DWHHiaA09z5GmOPPALr_5ZFw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Low Serum Folate Level and Increased Risk of Invasive Cervical Cancer in Bangladeshi Women</title><source>Bangladesh Journals Online</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Ferdous, Jannatul ; Khatun, Sabera ; Biswas, Subrata Kumar ; Pervin, Shahana ; Akter, Latifa ; Keya, Kashfia Ahmed ; Joarder, Mita ; Khan, Jawad Mahruj</creator><creatorcontrib>Ferdous, Jannatul ; Khatun, Sabera ; Biswas, Subrata Kumar ; Pervin, Shahana ; Akter, Latifa ; Keya, Kashfia Ahmed ; Joarder, Mita ; Khan, Jawad Mahruj</creatorcontrib><description>Objective(s): The aim of this study was to evaluate the risk of cervical cancer in relation to serum concentrations of folate.Materials and methods: This case-control study was conducted in the Gynaecologic Oncology Division of Bangabandhu Sheikh Mujib Medical University from November 2015-October 2016. For this study 50 patients with invasive cervical cancer were taken as study population and 50 healthy women of VIA or paps negative were taken as control to observe and compare serum folate level. Exclusion criteria were women with conditions associated with low folate level. Outcome variable was serum folate level and a p value of &lt; 0.05 was considered as significant.Results: Most of the participants belonged to age group 35 to 55 years in both the groups. Most of the study cases had low income status than the control group. Maximum patients with cervical cancer took OCP in comparison to control. Majority of the patients with cervical cancer had significantly low level of serum folate (&lt;2.7ng/ml) than those in the control group (2.7-16.1ng/ml), p=000.Conclusion: A significantly low level of serum folate, was observed in patients with invasive cervical cancer. So dietary interventions with folate supplementation might have some role in prevention of cervical carcinoma.Bangladesh J Obstet Gynaecol, 2016; Vol. 31(1) : 23-27</description><identifier>ISSN: 1018-4287</identifier><identifier>EISSN: 2408-8404</identifier><identifier>DOI: 10.3329/bjog.v31i1.34272</identifier><language>eng</language><ispartof>Bangladesh journal of obstetrics &amp; gynaecology, 2017-10, Vol.31 (1), p.23-27</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c158t-fe83045d6303b58de769a9c8802d3732f63517f8f86947419fbc4fc3e6b62dd83</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,4129,27933,27934</link.rule.ids></links><search><creatorcontrib>Ferdous, Jannatul</creatorcontrib><creatorcontrib>Khatun, Sabera</creatorcontrib><creatorcontrib>Biswas, Subrata Kumar</creatorcontrib><creatorcontrib>Pervin, Shahana</creatorcontrib><creatorcontrib>Akter, Latifa</creatorcontrib><creatorcontrib>Keya, Kashfia Ahmed</creatorcontrib><creatorcontrib>Joarder, Mita</creatorcontrib><creatorcontrib>Khan, Jawad Mahruj</creatorcontrib><title>Low Serum Folate Level and Increased Risk of Invasive Cervical Cancer in Bangladeshi Women</title><title>Bangladesh journal of obstetrics &amp; gynaecology</title><description>Objective(s): The aim of this study was to evaluate the risk of cervical cancer in relation to serum concentrations of folate.Materials and methods: This case-control study was conducted in the Gynaecologic Oncology Division of Bangabandhu Sheikh Mujib Medical University from November 2015-October 2016. For this study 50 patients with invasive cervical cancer were taken as study population and 50 healthy women of VIA or paps negative were taken as control to observe and compare serum folate level. Exclusion criteria were women with conditions associated with low folate level. Outcome variable was serum folate level and a p value of &lt; 0.05 was considered as significant.Results: Most of the participants belonged to age group 35 to 55 years in both the groups. Most of the study cases had low income status than the control group. Maximum patients with cervical cancer took OCP in comparison to control. Majority of the patients with cervical cancer had significantly low level of serum folate (&lt;2.7ng/ml) than those in the control group (2.7-16.1ng/ml), p=000.Conclusion: A significantly low level of serum folate, was observed in patients with invasive cervical cancer. So dietary interventions with folate supplementation might have some role in prevention of cervical carcinoma.Bangladesh J Obstet Gynaecol, 2016; Vol. 31(1) : 23-27</description><issn>1018-4287</issn><issn>2408-8404</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNot0F9LwzAUBfAgCo65dx_zBTqT3DRNH7U4HRQE_yD4UtLkZmZ2rSSz4re3m96XAxfOefgRcsnZEkCUV-122CxH4IEvQYpCnJCZkExnWjJ5SmaccZ1JoYtzskhpy6abWiDVjLzVwzd9wvi1o6uhM3ukNY7YUdM7uu5tRJPQ0ceQPujgp89oUhiRVhjHYE1HK9NbjDT09Mb0m844TO-Bvg477C_ImTddwsV_zsnL6va5us_qh7t1dV1nlud6n3nUwGTuFDBoc-2wUKUprdZMOChAeAU5L7z2WpWykLz0rZXeAqpWCec0zAn727VxSCmibz5j2Jn403DWHHiaA09z5GmOPPALr_5ZFw</recordid><startdate>20171012</startdate><enddate>20171012</enddate><creator>Ferdous, Jannatul</creator><creator>Khatun, Sabera</creator><creator>Biswas, Subrata Kumar</creator><creator>Pervin, Shahana</creator><creator>Akter, Latifa</creator><creator>Keya, Kashfia Ahmed</creator><creator>Joarder, Mita</creator><creator>Khan, Jawad Mahruj</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20171012</creationdate><title>Low Serum Folate Level and Increased Risk of Invasive Cervical Cancer in Bangladeshi Women</title><author>Ferdous, Jannatul ; Khatun, Sabera ; Biswas, Subrata Kumar ; Pervin, Shahana ; Akter, Latifa ; Keya, Kashfia Ahmed ; Joarder, Mita ; Khan, Jawad Mahruj</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c158t-fe83045d6303b58de769a9c8802d3732f63517f8f86947419fbc4fc3e6b62dd83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Ferdous, Jannatul</creatorcontrib><creatorcontrib>Khatun, Sabera</creatorcontrib><creatorcontrib>Biswas, Subrata Kumar</creatorcontrib><creatorcontrib>Pervin, Shahana</creatorcontrib><creatorcontrib>Akter, Latifa</creatorcontrib><creatorcontrib>Keya, Kashfia Ahmed</creatorcontrib><creatorcontrib>Joarder, Mita</creatorcontrib><creatorcontrib>Khan, Jawad Mahruj</creatorcontrib><collection>CrossRef</collection><jtitle>Bangladesh journal of obstetrics &amp; gynaecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ferdous, Jannatul</au><au>Khatun, Sabera</au><au>Biswas, Subrata Kumar</au><au>Pervin, Shahana</au><au>Akter, Latifa</au><au>Keya, Kashfia Ahmed</au><au>Joarder, Mita</au><au>Khan, Jawad Mahruj</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Low Serum Folate Level and Increased Risk of Invasive Cervical Cancer in Bangladeshi Women</atitle><jtitle>Bangladesh journal of obstetrics &amp; gynaecology</jtitle><date>2017-10-12</date><risdate>2017</risdate><volume>31</volume><issue>1</issue><spage>23</spage><epage>27</epage><pages>23-27</pages><issn>1018-4287</issn><eissn>2408-8404</eissn><abstract>Objective(s): The aim of this study was to evaluate the risk of cervical cancer in relation to serum concentrations of folate.Materials and methods: This case-control study was conducted in the Gynaecologic Oncology Division of Bangabandhu Sheikh Mujib Medical University from November 2015-October 2016. For this study 50 patients with invasive cervical cancer were taken as study population and 50 healthy women of VIA or paps negative were taken as control to observe and compare serum folate level. Exclusion criteria were women with conditions associated with low folate level. Outcome variable was serum folate level and a p value of &lt; 0.05 was considered as significant.Results: Most of the participants belonged to age group 35 to 55 years in both the groups. Most of the study cases had low income status than the control group. Maximum patients with cervical cancer took OCP in comparison to control. Majority of the patients with cervical cancer had significantly low level of serum folate (&lt;2.7ng/ml) than those in the control group (2.7-16.1ng/ml), p=000.Conclusion: A significantly low level of serum folate, was observed in patients with invasive cervical cancer. So dietary interventions with folate supplementation might have some role in prevention of cervical carcinoma.Bangladesh J Obstet Gynaecol, 2016; Vol. 31(1) : 23-27</abstract><doi>10.3329/bjog.v31i1.34272</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1018-4287
ispartof Bangladesh journal of obstetrics & gynaecology, 2017-10, Vol.31 (1), p.23-27
issn 1018-4287
2408-8404
language eng
recordid cdi_crossref_primary_10_3329_bjog_v31i1_34272
source Bangladesh Journals Online; EZB-FREE-00999 freely available EZB journals
title Low Serum Folate Level and Increased Risk of Invasive Cervical Cancer in Bangladeshi Women
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-03T12%3A42%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Low%20Serum%20Folate%20Level%20and%20Increased%20Risk%20of%20Invasive%20Cervical%20Cancer%20in%20Bangladeshi%20Women&rft.jtitle=Bangladesh%20journal%20of%20obstetrics%20&%20gynaecology&rft.au=Ferdous,%20Jannatul&rft.date=2017-10-12&rft.volume=31&rft.issue=1&rft.spage=23&rft.epage=27&rft.pages=23-27&rft.issn=1018-4287&rft.eissn=2408-8404&rft_id=info:doi/10.3329/bjog.v31i1.34272&rft_dat=%3Ccrossref%3E10_3329_bjog_v31i1_34272%3C/crossref%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true