Losartan inhibits in vitro platelet activation: comparison with candesartan and valsartan

A recent study has shown that losartan, an AT1-receptor antagonist, interacts with thromboxane A2 (TxA2)/prostaglandin H2 (PGH2) receptors in human platelets. The aim of the present study was to analyse the ability of different angiotensin II (Ang II) AT1-receptor antagonists to inhibit TxA2-depende...

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Veröffentlicht in:	Journal of the renin-angiotensin-aldosterone system 2000-06, Vol.1 (2), p.175-179
Hauptverfasser:	Núñez, Antonio, Gómez, Juan, Zalba, Luis Rico, Montón, Mercedes, Jiménez, Ana, Velasco, Sandra, López-Blaya, Almudena, Celdrán Uriarte, Angel, Casado, Santos, López-Farré, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - pharmacology Adult Angiotensin Receptor Antagonists Benzimidazoles - pharmacology Blood Platelets - drug effects Blood Platelets - physiology Cells, Cultured Drug Interactions Humans Losartan - pharmacology Male Platelet Activation - drug effects Platelet Aggregation Inhibitors - pharmacology Receptor, Angiotensin, Type 1 Tetrazoles - pharmacology Thromboxane A2 - pharmacology Valine - analogs & derivatives Valine - pharmacology Valsartan
Online-Zugang:	Volltext
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