Serum antioxidant status in Iraqi women with endometrial cancer

Background: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers.Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with e...

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Veröffentlicht in:Journal of the Faculty of Medicine, Baghdad Baghdad, 2016-01, Vol.58 (4), p.378-383
Hauptverfasser: Al- Ruba,ei, Salwa H. N., Jasim, Rana K., Al-Rawaq, Khudhair J. S.
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container_issue 4
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container_title Journal of the Faculty of Medicine, Baghdad
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creator Al- Ruba,ei, Salwa H. N.
Jasim, Rana K.
Al-Rawaq, Khudhair J. S.
description Background: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers.Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with endometrial cancer.Patients and methods: Fifty six endometrial cancer women patients with various clinical stages (stage 1A, stage1B, stage II, stage III, stage IV) mean aged 58.055 ± 10.561 years, and 30 healthy women volunteers mean aged 39.731 ± 13.504 years, were includes as control group.Results: The results in this study revealed a highly significant decreased (P
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S.</creator><creatorcontrib>Al- Ruba,ei, Salwa H. N. ; Jasim, Rana K. ; Al-Rawaq, Khudhair J. S.</creatorcontrib><description>Background: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers.Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with endometrial cancer.Patients and methods: Fifty six endometrial cancer women patients with various clinical stages (stage 1A, stage1B, stage II, stage III, stage IV) mean aged 58.055 ± 10.561 years, and 30 healthy women volunteers mean aged 39.731 ± 13.504 years, were includes as control group.Results: The results in this study revealed a highly significant decreased (P&lt;0.01) in β- carotene, Vitamin E and significant increased (P&lt;0.01) in (Uric acid and MDA). The results of ( Coenzyme Q10 and Vitamins (A, C) showed a significant decreased (P&lt;0.05), in the sera levels of patients with endometrial cancer as compared to control group.Conclusions: This study suggest that high levels of oxidative stress and low levels of antioxidant defense system may be associated with increased the risks of endometrial cancer.</description><identifier>ISSN: 0041-9419</identifier><identifier>EISSN: 2410-8057</identifier><identifier>DOI: 10.32007/jfacmedbagdad.584289</identifier><language>eng</language><ispartof>Journal of the Faculty of Medicine, Baghdad, 2016-01, Vol.58 (4), p.378-383</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Al- Ruba,ei, Salwa H. 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S.</creatorcontrib><title>Serum antioxidant status in Iraqi women with endometrial cancer</title><title>Journal of the Faculty of Medicine, Baghdad</title><description>Background: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers.Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with endometrial cancer.Patients and methods: Fifty six endometrial cancer women patients with various clinical stages (stage 1A, stage1B, stage II, stage III, stage IV) mean aged 58.055 ± 10.561 years, and 30 healthy women volunteers mean aged 39.731 ± 13.504 years, were includes as control group.Results: The results in this study revealed a highly significant decreased (P&lt;0.01) in β- carotene, Vitamin E and significant increased (P&lt;0.01) in (Uric acid and MDA). The results of ( Coenzyme Q10 and Vitamins (A, C) showed a significant decreased (P&lt;0.05), in the sera levels of patients with endometrial cancer as compared to control group.Conclusions: This study suggest that high levels of oxidative stress and low levels of antioxidant defense system may be associated with increased the risks of endometrial cancer.</description><issn>0041-9419</issn><issn>2410-8057</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqdjkEKwjAURIMoWNQjCLlA9adNabpyIYqudR--TaqRNtUkot7eom7cOpvHDAw8QqYMZmkCkM_PFZaNVgc8KlSzTPBEFD0SJZxBLCDL-yQC4CwuOCuGZOL9GbqIbhM8IouddreGog2mfRjVkfqA4eapsXTr8GrovW20pXcTTlRb1ZXgDNa0RFtqNyaDCmuvJ1-OSLZe7ZebuHSt905X8uJMg-4pGci3sPwRlh_h9N_fCyOwUAw</recordid><startdate>20160103</startdate><enddate>20160103</enddate><creator>Al- Ruba,ei, Salwa H. N.</creator><creator>Jasim, Rana K.</creator><creator>Al-Rawaq, Khudhair J. 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S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Serum antioxidant status in Iraqi women with endometrial cancer</atitle><jtitle>Journal of the Faculty of Medicine, Baghdad</jtitle><date>2016-01-03</date><risdate>2016</risdate><volume>58</volume><issue>4</issue><spage>378</spage><epage>383</epage><pages>378-383</pages><issn>0041-9419</issn><eissn>2410-8057</eissn><abstract>Background: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers.Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with endometrial cancer.Patients and methods: Fifty six endometrial cancer women patients with various clinical stages (stage 1A, stage1B, stage II, stage III, stage IV) mean aged 58.055 ± 10.561 years, and 30 healthy women volunteers mean aged 39.731 ± 13.504 years, were includes as control group.Results: The results in this study revealed a highly significant decreased (P&lt;0.01) in β- carotene, Vitamin E and significant increased (P&lt;0.01) in (Uric acid and MDA). 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