Synthesis of a Chiral β-Amino Acid Derivative by a Cobalt-Catalysed Coupling Reaction

A chiral β-amino acid derivative was synthesised by a cobalt-catalysed alkylation of 2,4,5-trifluorophenyl magnesium bromide with the alkyl halide derivative of L-aspartic acid, using an efficient catalytic reagent: CoCl 2 /TMEDA. The halide derivative was synthesised from protected L-aspartic acid...

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Veröffentlicht in:	Journal of chemical research 2011-09, Vol.35 (9), p.545-546
Hauptverfasser:	Pan, Xianhua, Yu, Wansheng, Ou, Wenhua, Tao, Xiaohu, Wan, Jiaomei, Liu, Feng
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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