Enhanced phagocytosis of rat alveolar macrophages by intravenous infusion of an arginine-enriched solution
Phagocytosis of rat alveolar macrophages (AM) was enhanced by the infusion of arginine-rich solution for 7 days. The enhancement of phagocytosis by arginine-rich solution was due to not the difference in the distribution of AM subpopulations (I to IV) but the difference in phagocytic activity of AM...
Gespeichert in:
| Veröffentlicht in: | Journal of Nutritional Science and Vitaminology 1992, Vol.38(6), pp.565-578 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 578 |
|---|---|
| container_issue | 6 |
| container_start_page | 565 |
| container_title | Journal of Nutritional Science and Vitaminology |
| container_volume | 38 |
| creator | NII, Yoshitaka MORIGUCHI, Satoru KISHINO, Yasuo |
| description | Phagocytosis of rat alveolar macrophages (AM) was enhanced by the infusion of arginine-rich solution for 7 days. The enhancement of phagocytosis by arginine-rich solution was due to not the difference in the distribution of AM subpopulations (I to IV) but the difference in phagocytic activity of AM in fraction IV. In the process of phagocy-tosis, there were no significant differences in the stages of migration, attachment, and digestion between control and arginine-rich solutions, although AM from fraction IV of rats infused with arginine-rich solution showed significantly higher ingestion of opsonized sheep red blood cells (SRBC) compared to that of control group. Furthermore, the production of macrophage-activating factor (MAF) from rat splenocytes was higher in arginine-rich group than that of control group. AM from fraction IV of rats fed a stock diet had a higher arginase activity and showed a significant increase of Phagocytosis following in vitro incubation with L-arginine (25 and 50mM) for 24 h. From these results, the enhanced phagocytosis of AM by arginine-rich solution may be due to the increased phagocytosis of AM from fraction IV, in which the higher sensitivity of AM from fraction IV to arginine and the higher production of MAF from splenocytes following the infusion of arginine-rich solution participate. |
| doi_str_mv | 10.3177/jnsv.38.565 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_crossref_primary_10_3177_jnsv_38_565</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>73536564</sourcerecordid><originalsourceid>FETCH-LOGICAL-c460t-379c88ad738f84640089a1f801c01137e75b17154001f035e007c2a2f05eaad43</originalsourceid><addsrcrecordid>eNqNkc-PEyEcxYnRrHX15FkzJy9m6peBGZjjpq4_N9GDeiXfUmhpplCBqel_L-Nsulc5AMn78Hg8CHlJYcmoEO_2Pp2WTC7brn1EFlRKWgvBm8dkAQxozSXAU_IspT0A7yWXV-SKMuAd0AXZ3_odem021XGH26DPOSSXqmCriLnC4WTCgLE6oI5hIkyq1ufK-RzxZHwYU9nbMbngpzPoK4xb5503tfHR6V0xTmEYcwGekycWh2Re3K_X5OeH2x-rT_Xdt4-fVzd3tS6Rcs1Er6XEjWDSSt5xANkjtRKoBkqZMKJdU0HbIlALrDUAQjfYWGgN4oaza_Jm9j3G8Hs0KauDS9oMA3pTAivBWta13QS-ncHytpSiseoY3QHjWVFQU7NqalYxqUqzhX51bzuuD2bzwM5VFl3O-h-zDjZpZ0qtF-qG9n3z9VfTNFAGX7mMUyerMPr8EOR_jhb6_UzvUy4fcuEwZqcH8y807QWbgnfzVPJfZL3DqIwvNq9nG4tB4Ta6pL58L1eVXjvadJT9Bd0luBY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73536564</pqid></control><display><type>article</type><title>Enhanced phagocytosis of rat alveolar macrophages by intravenous infusion of an arginine-enriched solution</title><source>J-STAGE Free</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>NII, Yoshitaka ; MORIGUCHI, Satoru ; KISHINO, Yasuo</creator><creatorcontrib>NII, Yoshitaka ; MORIGUCHI, Satoru ; KISHINO, Yasuo ; Tokushima Univ. (Japan). School of Medicine</creatorcontrib><description>Phagocytosis of rat alveolar macrophages (AM) was enhanced by the infusion of arginine-rich solution for 7 days. The enhancement of phagocytosis by arginine-rich solution was due to not the difference in the distribution of AM subpopulations (I to IV) but the difference in phagocytic activity of AM in fraction IV. In the process of phagocy-tosis, there were no significant differences in the stages of migration, attachment, and digestion between control and arginine-rich solutions, although AM from fraction IV of rats infused with arginine-rich solution showed significantly higher ingestion of opsonized sheep red blood cells (SRBC) compared to that of control group. Furthermore, the production of macrophage-activating factor (MAF) from rat splenocytes was higher in arginine-rich group than that of control group. AM from fraction IV of rats fed a stock diet had a higher arginase activity and showed a significant increase of Phagocytosis following in vitro incubation with L-arginine (25 and 50mM) for 24 h. From these results, the enhanced phagocytosis of AM by arginine-rich solution may be due to the increased phagocytosis of AM from fraction IV, in which the higher sensitivity of AM from fraction IV to arginine and the higher production of MAF from splenocytes following the infusion of arginine-rich solution participate.</description><identifier>ISSN: 0301-4800</identifier><identifier>EISSN: 1881-7742</identifier><identifier>DOI: 10.3177/jnsv.38.565</identifier><identifier>PMID: 1304601</identifier><language>eng</language><publisher>TOKYO: Center for Academic Publications Japan</publisher><subject>alveolar macrophages ; Amino Acids - blood ; Animals ; Arginase - metabolism ; arginina ; arginine ; Arginine - administration & dosage ; Arginine - pharmacology ; blood vessels ; Body Weight ; Cathepsin B - metabolism ; Cell Count ; Cell Movement ; fagocitos ; human nutrition ; Kinetics ; Life Sciences & Biomedicine ; macrophage-activating factor ; Macrophage-Activating Factors - pharmacology ; Macrophages, Alveolar - cytology ; Macrophages, Alveolar - physiology ; Male ; nutricion humana ; Nutrition & Dietetics ; nutrition humaine ; Organ Size ; phagocyte ; phagocytes ; phagocytosis ; Phagocytosis - drug effects ; rat ; rata ; Rats ; Rats, Inbred F344 ; Science & Technology ; Solutions ; Spleen - cytology ; Thymus Gland - cytology ; vaisseau sanguin ; vasos sanguineos</subject><ispartof>Journal of Nutritional Science and Vitaminology, 1992, Vol.38(6), pp.565-578</ispartof><rights>the Center for Academic Publications Japan</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>4</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wosA1992KV22200004</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c460t-379c88ad738f84640089a1f801c01137e75b17154001f035e007c2a2f05eaad43</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,1884,4025,27927,27928,27929</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1304601$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>NII, Yoshitaka</creatorcontrib><creatorcontrib>MORIGUCHI, Satoru</creatorcontrib><creatorcontrib>KISHINO, Yasuo</creatorcontrib><creatorcontrib>Tokushima Univ. (Japan). School of Medicine</creatorcontrib><title>Enhanced phagocytosis of rat alveolar macrophages by intravenous infusion of an arginine-enriched solution</title><title>Journal of Nutritional Science and Vitaminology</title><addtitle>J NUTR SCI VITAMINOL</addtitle><addtitle>J Nutr Sci Vitaminol</addtitle><description>Phagocytosis of rat alveolar macrophages (AM) was enhanced by the infusion of arginine-rich solution for 7 days. The enhancement of phagocytosis by arginine-rich solution was due to not the difference in the distribution of AM subpopulations (I to IV) but the difference in phagocytic activity of AM in fraction IV. In the process of phagocy-tosis, there were no significant differences in the stages of migration, attachment, and digestion between control and arginine-rich solutions, although AM from fraction IV of rats infused with arginine-rich solution showed significantly higher ingestion of opsonized sheep red blood cells (SRBC) compared to that of control group. Furthermore, the production of macrophage-activating factor (MAF) from rat splenocytes was higher in arginine-rich group than that of control group. AM from fraction IV of rats fed a stock diet had a higher arginase activity and showed a significant increase of Phagocytosis following in vitro incubation with L-arginine (25 and 50mM) for 24 h. From these results, the enhanced phagocytosis of AM by arginine-rich solution may be due to the increased phagocytosis of AM from fraction IV, in which the higher sensitivity of AM from fraction IV to arginine and the higher production of MAF from splenocytes following the infusion of arginine-rich solution participate.</description><subject>alveolar macrophages</subject><subject>Amino Acids - blood</subject><subject>Animals</subject><subject>Arginase - metabolism</subject><subject>arginina</subject><subject>arginine</subject><subject>Arginine - administration & dosage</subject><subject>Arginine - pharmacology</subject><subject>blood vessels</subject><subject>Body Weight</subject><subject>Cathepsin B - metabolism</subject><subject>Cell Count</subject><subject>Cell Movement</subject><subject>fagocitos</subject><subject>human nutrition</subject><subject>Kinetics</subject><subject>Life Sciences & Biomedicine</subject><subject>macrophage-activating factor</subject><subject>Macrophage-Activating Factors - pharmacology</subject><subject>Macrophages, Alveolar - cytology</subject><subject>Macrophages, Alveolar - physiology</subject><subject>Male</subject><subject>nutricion humana</subject><subject>Nutrition & Dietetics</subject><subject>nutrition humaine</subject><subject>Organ Size</subject><subject>phagocyte</subject><subject>phagocytes</subject><subject>phagocytosis</subject><subject>Phagocytosis - drug effects</subject><subject>rat</subject><subject>rata</subject><subject>Rats</subject><subject>Rats, Inbred F344</subject><subject>Science & Technology</subject><subject>Solutions</subject><subject>Spleen - cytology</subject><subject>Thymus Gland - cytology</subject><subject>vaisseau sanguin</subject><subject>vasos sanguineos</subject><issn>0301-4800</issn><issn>1881-7742</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EZCTM</sourceid><sourceid>EIF</sourceid><recordid>eNqNkc-PEyEcxYnRrHX15FkzJy9m6peBGZjjpq4_N9GDeiXfUmhpplCBqel_L-Nsulc5AMn78Hg8CHlJYcmoEO_2Pp2WTC7brn1EFlRKWgvBm8dkAQxozSXAU_IspT0A7yWXV-SKMuAd0AXZ3_odem021XGH26DPOSSXqmCriLnC4WTCgLE6oI5hIkyq1ufK-RzxZHwYU9nbMbngpzPoK4xb5503tfHR6V0xTmEYcwGekycWh2Re3K_X5OeH2x-rT_Xdt4-fVzd3tS6Rcs1Er6XEjWDSSt5xANkjtRKoBkqZMKJdU0HbIlALrDUAQjfYWGgN4oaza_Jm9j3G8Hs0KauDS9oMA3pTAivBWta13QS-ncHytpSiseoY3QHjWVFQU7NqalYxqUqzhX51bzuuD2bzwM5VFl3O-h-zDjZpZ0qtF-qG9n3z9VfTNFAGX7mMUyerMPr8EOR_jhb6_UzvUy4fcuEwZqcH8y807QWbgnfzVPJfZL3DqIwvNq9nG4tB4Ta6pL58L1eVXjvadJT9Bd0luBY</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>NII, Yoshitaka</creator><creator>MORIGUCHI, Satoru</creator><creator>KISHINO, Yasuo</creator><general>Center for Academic Publications Japan</general><general>Center Academic Publ Japan</general><scope>FBQ</scope><scope>BLEPL</scope><scope>DTL</scope><scope>EZCTM</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1992</creationdate><title>Enhanced phagocytosis of rat alveolar macrophages by intravenous infusion of an arginine-enriched solution</title><author>NII, Yoshitaka ; MORIGUCHI, Satoru ; KISHINO, Yasuo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c460t-379c88ad738f84640089a1f801c01137e75b17154001f035e007c2a2f05eaad43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>alveolar macrophages</topic><topic>Amino Acids - blood</topic><topic>Animals</topic><topic>Arginase - metabolism</topic><topic>arginina</topic><topic>arginine</topic><topic>Arginine - administration & dosage</topic><topic>Arginine - pharmacology</topic><topic>blood vessels</topic><topic>Body Weight</topic><topic>Cathepsin B - metabolism</topic><topic>Cell Count</topic><topic>Cell Movement</topic><topic>fagocitos</topic><topic>human nutrition</topic><topic>Kinetics</topic><topic>Life Sciences & Biomedicine</topic><topic>macrophage-activating factor</topic><topic>Macrophage-Activating Factors - pharmacology</topic><topic>Macrophages, Alveolar - cytology</topic><topic>Macrophages, Alveolar - physiology</topic><topic>Male</topic><topic>nutricion humana</topic><topic>Nutrition & Dietetics</topic><topic>nutrition humaine</topic><topic>Organ Size</topic><topic>phagocyte</topic><topic>phagocytes</topic><topic>phagocytosis</topic><topic>Phagocytosis - drug effects</topic><topic>rat</topic><topic>rata</topic><topic>Rats</topic><topic>Rats, Inbred F344</topic><topic>Science & Technology</topic><topic>Solutions</topic><topic>Spleen - cytology</topic><topic>Thymus Gland - cytology</topic><topic>vaisseau sanguin</topic><topic>vasos sanguineos</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>NII, Yoshitaka</creatorcontrib><creatorcontrib>MORIGUCHI, Satoru</creatorcontrib><creatorcontrib>KISHINO, Yasuo</creatorcontrib><creatorcontrib>Tokushima Univ. (Japan). School of Medicine</creatorcontrib><collection>AGRIS</collection><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 1992</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Nutritional Science and Vitaminology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>NII, Yoshitaka</au><au>MORIGUCHI, Satoru</au><au>KISHINO, Yasuo</au><aucorp>Tokushima Univ. (Japan). School of Medicine</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enhanced phagocytosis of rat alveolar macrophages by intravenous infusion of an arginine-enriched solution</atitle><jtitle>Journal of Nutritional Science and Vitaminology</jtitle><stitle>J NUTR SCI VITAMINOL</stitle><addtitle>J Nutr Sci Vitaminol</addtitle><date>1992</date><risdate>1992</risdate><volume>38</volume><issue>6</issue><spage>565</spage><epage>578</epage><pages>565-578</pages><issn>0301-4800</issn><eissn>1881-7742</eissn><abstract>Phagocytosis of rat alveolar macrophages (AM) was enhanced by the infusion of arginine-rich solution for 7 days. The enhancement of phagocytosis by arginine-rich solution was due to not the difference in the distribution of AM subpopulations (I to IV) but the difference in phagocytic activity of AM in fraction IV. In the process of phagocy-tosis, there were no significant differences in the stages of migration, attachment, and digestion between control and arginine-rich solutions, although AM from fraction IV of rats infused with arginine-rich solution showed significantly higher ingestion of opsonized sheep red blood cells (SRBC) compared to that of control group. Furthermore, the production of macrophage-activating factor (MAF) from rat splenocytes was higher in arginine-rich group than that of control group. AM from fraction IV of rats fed a stock diet had a higher arginase activity and showed a significant increase of Phagocytosis following in vitro incubation with L-arginine (25 and 50mM) for 24 h. From these results, the enhanced phagocytosis of AM by arginine-rich solution may be due to the increased phagocytosis of AM from fraction IV, in which the higher sensitivity of AM from fraction IV to arginine and the higher production of MAF from splenocytes following the infusion of arginine-rich solution participate.</abstract><cop>TOKYO</cop><pub>Center for Academic Publications Japan</pub><pmid>1304601</pmid><doi>10.3177/jnsv.38.565</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0301-4800 |
| ispartof | Journal of Nutritional Science and Vitaminology, 1992, Vol.38(6), pp.565-578 |
| issn | 0301-4800 1881-7742 |
| language | eng |
| recordid | cdi_crossref_primary_10_3177_jnsv_38_565 |
| source | J-STAGE Free; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | alveolar macrophages Amino Acids - blood Animals Arginase - metabolism arginina arginine Arginine - administration & dosage Arginine - pharmacology blood vessels Body Weight Cathepsin B - metabolism Cell Count Cell Movement fagocitos human nutrition Kinetics Life Sciences & Biomedicine macrophage-activating factor Macrophage-Activating Factors - pharmacology Macrophages, Alveolar - cytology Macrophages, Alveolar - physiology Male nutricion humana Nutrition & Dietetics nutrition humaine Organ Size phagocyte phagocytes phagocytosis Phagocytosis - drug effects rat rata Rats Rats, Inbred F344 Science & Technology Solutions Spleen - cytology Thymus Gland - cytology vaisseau sanguin vasos sanguineos |
| title | Enhanced phagocytosis of rat alveolar macrophages by intravenous infusion of an arginine-enriched solution |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T23%3A02%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Enhanced%20phagocytosis%20of%20rat%20alveolar%20macrophages%20by%20intravenous%20infusion%20of%20an%20arginine-enriched%20solution&rft.jtitle=Journal%20of%20Nutritional%20Science%20and%20Vitaminology&rft.au=NII,%20Yoshitaka&rft.aucorp=Tokushima%20Univ.%20(Japan).%20School%20of%20Medicine&rft.date=1992&rft.volume=38&rft.issue=6&rft.spage=565&rft.epage=578&rft.pages=565-578&rft.issn=0301-4800&rft.eissn=1881-7742&rft_id=info:doi/10.3177/jnsv.38.565&rft_dat=%3Cproquest_cross%3E73536564%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=73536564&rft_id=info:pmid/1304601&rfr_iscdi=true |