Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium

Diffuse intrinsic pontine glioma is a lethal childhood brain cancer with dismal prognosis and MR imaging is the primary methodology used for diagnosis and monitoring. Our aim was to determine whether advanced diffusion, perfusion, and permeability MR imaging metrics predict survival and pseudoprogre...

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Veröffentlicht in:	American journal of neuroradiology : AJNR 2020-04, Vol.41 (4), p.718-724
Hauptverfasser:	Vajapeyam, S, Brown, D, Billups, C, Patay, Z, Vezina, G, Shiroishi, M S, Law, M, Baxter, P, Onar-Thomas, A, Fangusaro, J R, Dunkel, I J, Poussaint, T Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Algorithms Antineoplastic Combined Chemotherapy Protocols - therapeutic use Benchmarking Benzimidazoles - administration & dosage Brain Stem Neoplasms - diagnostic imaging Brain Stem Neoplasms - mortality Brain Stem Neoplasms - therapy Chemoradiotherapy - methods Child Diffuse Intrinsic Pontine Glioma - diagnostic imaging Diffuse Intrinsic Pontine Glioma - mortality Diffuse Intrinsic Pontine Glioma - therapy Disease Progression Female Functional Humans Image Interpretation, Computer-Assisted - methods Image Interpretation, Computer-Assisted - standards Magnetic Resonance Imaging - methods Male Neuroimaging - methods Neuroimaging - standards Pediatrics Perfusion Imaging - methods Prognosis Retrospective Studies Survival Analysis Temozolomide - administration & dosage
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