The role of exosomes in the pathogenesis of chemotherapy-induced cardiotoxicity: A diagnostic and prognostic approach: exosome and cardiotoxicity: exosome and cardiotoxicity

The role of exosomes in the pathogenesis of chemotherapy-induced cardiotoxicity: A diagnostic and prognostic approach: exosome and cardiotoxicity: exosome and cardiotoxicity

Exosomes are a subtype of natural extracellular vesicles that transfer a great number of biomolecules, released by almost all types of cells, and can be specifically taken up by recipient cells in order to maintain homeostasis and induce a proper response to stress or harsh environmental conditions....

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Veröffentlicht in:Galen 2023-12, Vol.12
Hauptverfasser: Jafari, Negar, Kazeminia, Syedeh Sara, Hamedi, Zahra, Zamanifard, Somayeh, Aslanabadi, Naser, Goudarzi, Mohammad, Amini, Reza, Samadi, Parisa
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container_title Galen
container_volume 12
creator Jafari, Negar
Kazeminia, Syedeh Sara
Hamedi, Zahra
Zamanifard, Somayeh
Aslanabadi, Naser
Goudarzi, Mohammad
Amini, Reza
Samadi, Parisa
description Exosomes are a subtype of natural extracellular vesicles that transfer a great number of biomolecules, released by almost all types of cells, and can be specifically taken up by recipient cells in order to maintain homeostasis and induce a proper response to stress or harsh environmental conditions. Since the heart is part of complex systems which involve various cell types, exosome-mediated communication plays a crucial role in the cardiovascular field. Given the extended studies on the molecular mechanisms mediated by exosome cargos, leading to cardiovascular diseases, we focus on the most important data that report the roles of proteins and microRNAs (miRNAs) transferred by exosomes and whether they possess cardiotoxicity or cardioprotection and also the potential of these biomolecules as therapeutic tools or diagnostic biomarkers.
doi_str_mv 10.31661/gmj.v12i.2534
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title The role of exosomes in the pathogenesis of chemotherapy-induced cardiotoxicity: A diagnostic and prognostic approach: exosome and cardiotoxicity: exosome and cardiotoxicity
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