AUC-Dependent Cytotoxicity of Cyclophosphamide against Human Tumors Transplanted into Nude Mice

We studied the cytotoxicity of cyclophosphamide following the administration of phenobarbital or chloral hydrate to nude mice bearing human tumor xenografts. Cyclophosphamide, 60mg/kg, was injected intraperitoneally once a week for four weeks. The antitumor efficacy of cyclophosphamide was not alter...

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Veröffentlicht in:	Journal of Clinical Biochemistry and Nutrition 1986, Vol.1(2), pp.171-179
Hauptverfasser:	SUGIYAMA, Masatoshi, OKAMURA, Kentarou, GOTO, Mitsuyoshi, KITANO, Morihisa
Format:	Artikel
Sprache:	eng
Schlagworte:	AUC chloral hydrate cyclophosphamide NBP-alkylating metabolites phenobarbital
Online-Zugang:	Volltext
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