Inhibitory effect of cortisol on the defense activities of tilapia neutrophils in vitro
On the premise that fish neutrophil activities are depressed under stressed conditions, this study investigated the direct effect of cortisol on the in vitro activity of neutrophiles collected from tilapia Oreochromis niloticus. Neutrophils were obtained from swim bladders and exposed to different l...
Gespeichert in:
| Veröffentlicht in: | Fish Pathology 2002/03/15, Vol.37(1), pp.13-16 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 16 |
|---|---|
| container_issue | 1 |
| container_start_page | 13 |
| container_title | Fish Pathology |
| container_volume | 37 |
| creator | Kurogi, J. (Kagoshima Univ. (Japan)) Iida, T |
| description | On the premise that fish neutrophil activities are depressed under stressed conditions, this study investigated the direct effect of cortisol on the in vitro activity of neutrophiles collected from tilapia Oreochromis niloticus. Neutrophils were obtained from swim bladders and exposed to different levels of cortisol (0-1000 ng/mL), and their chemotactic, phagocytic and respiratory burst activities were assessed. This treatment suppressed neutrophil activities as seen in the reduction of chemotactic, phagocytic and respiratory burst activities. Neutrophil activities appeared to be suppressed in a dose-dependent manner leading to a considerable reduction in neutrophil activities with high concentrations of cortisol. Nevertheless, we showed that the respiratory burst activity was able to recover from the observed effect after cortisol was removed. The results in this study strongly suggest that cortisol has a directly adverse effect on fish neutrophil defense activities, but that the effect is reversible. |
| doi_str_mv | 10.3147/jsfp.37.13 |
| format | Article |
| fullrecord | <record><control><sourceid>fao_cross</sourceid><recordid>TN_cdi_crossref_primary_10_3147_jsfp_37_13</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JP2002003387</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-8c44a443c54f7ccc6740b7e1c49c7bcf015592dc483f3cdb16205d6d51d88c2b3</originalsourceid><addsrcrecordid>eNo90E1LAzEQBuAgCtbqxbuQs7A12clu0qMUPyoFPSh6C9nZpE1ZNyWJQv-921YKw8xhHl6YIeSaswlwIe_WyW0mICccTsiIK8ULCVCdkhEDpQqp1Nc5uUhpzVhVA4MR-Zz3K9_4HOKWWucsZhocxRCzT6Gjoad5ZWlrne2TpQaz__XZ27RT2Xdm4w3t7U-OYbPyXaK-pwOI4ZKcOdMle_U_x-Tj8eF99lwsXp_ms_tFgSDLXCgUwggBWAknEbGWgjXSchRTlA06xqtqWrYoFDjAtuF1yaq2biveKoVlA2Nye8jFGFKK1ulN9N8mbjVnevcSvXuJBqk5DHh2wOuUzdIeqRmuxc7uKZ_W9Z4fGofjFlcmatsPKTeHFGeCNsvok355KxkbCkBJ-AMB3HdT</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Inhibitory effect of cortisol on the defense activities of tilapia neutrophils in vitro</title><source>EZB Electronic Journals Library</source><creator>Kurogi, J. (Kagoshima Univ. (Japan)) ; Iida, T</creator><creatorcontrib>Kurogi, J. (Kagoshima Univ. (Japan)) ; Iida, T</creatorcontrib><description>On the premise that fish neutrophil activities are depressed under stressed conditions, this study investigated the direct effect of cortisol on the in vitro activity of neutrophiles collected from tilapia Oreochromis niloticus. Neutrophils were obtained from swim bladders and exposed to different levels of cortisol (0-1000 ng/mL), and their chemotactic, phagocytic and respiratory burst activities were assessed. This treatment suppressed neutrophil activities as seen in the reduction of chemotactic, phagocytic and respiratory burst activities. Neutrophil activities appeared to be suppressed in a dose-dependent manner leading to a considerable reduction in neutrophil activities with high concentrations of cortisol. Nevertheless, we showed that the respiratory burst activity was able to recover from the observed effect after cortisol was removed. The results in this study strongly suggest that cortisol has a directly adverse effect on fish neutrophil defense activities, but that the effect is reversible.</description><identifier>ISSN: 0388-788X</identifier><identifier>EISSN: 1881-7335</identifier><identifier>DOI: 10.3147/jsfp.37.13</identifier><language>eng</language><publisher>The Japanese Society of Fish Pathology</publisher><subject>cortisol ; DEFENCE MECHANISMS ; GLUCOCORTICOIDS ; GRANULOCYTES ; IN VITRO EXPERIMENTATION ; neutrophil activity ; OREOCHROMIS NILOTICUS ; stress ; tilapia</subject><ispartof>Fish Pathology, 2002/03/15, Vol.37(1), pp.13-16</ispartof><rights>The Japanese Society of Fish Pathology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-8c44a443c54f7ccc6740b7e1c49c7bcf015592dc483f3cdb16205d6d51d88c2b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids></links><search><creatorcontrib>Kurogi, J. (Kagoshima Univ. (Japan))</creatorcontrib><creatorcontrib>Iida, T</creatorcontrib><title>Inhibitory effect of cortisol on the defense activities of tilapia neutrophils in vitro</title><title>Fish Pathology</title><addtitle>Fish Pathol.</addtitle><description>On the premise that fish neutrophil activities are depressed under stressed conditions, this study investigated the direct effect of cortisol on the in vitro activity of neutrophiles collected from tilapia Oreochromis niloticus. Neutrophils were obtained from swim bladders and exposed to different levels of cortisol (0-1000 ng/mL), and their chemotactic, phagocytic and respiratory burst activities were assessed. This treatment suppressed neutrophil activities as seen in the reduction of chemotactic, phagocytic and respiratory burst activities. Neutrophil activities appeared to be suppressed in a dose-dependent manner leading to a considerable reduction in neutrophil activities with high concentrations of cortisol. Nevertheless, we showed that the respiratory burst activity was able to recover from the observed effect after cortisol was removed. The results in this study strongly suggest that cortisol has a directly adverse effect on fish neutrophil defense activities, but that the effect is reversible.</description><subject>cortisol</subject><subject>DEFENCE MECHANISMS</subject><subject>GLUCOCORTICOIDS</subject><subject>GRANULOCYTES</subject><subject>IN VITRO EXPERIMENTATION</subject><subject>neutrophil activity</subject><subject>OREOCHROMIS NILOTICUS</subject><subject>stress</subject><subject>tilapia</subject><issn>0388-788X</issn><issn>1881-7335</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNo90E1LAzEQBuAgCtbqxbuQs7A12clu0qMUPyoFPSh6C9nZpE1ZNyWJQv-921YKw8xhHl6YIeSaswlwIe_WyW0mICccTsiIK8ULCVCdkhEDpQqp1Nc5uUhpzVhVA4MR-Zz3K9_4HOKWWucsZhocxRCzT6Gjoad5ZWlrne2TpQaz__XZ27RT2Xdm4w3t7U-OYbPyXaK-pwOI4ZKcOdMle_U_x-Tj8eF99lwsXp_ms_tFgSDLXCgUwggBWAknEbGWgjXSchRTlA06xqtqWrYoFDjAtuF1yaq2biveKoVlA2Nye8jFGFKK1ulN9N8mbjVnevcSvXuJBqk5DHh2wOuUzdIeqRmuxc7uKZ_W9Z4fGofjFlcmatsPKTeHFGeCNsvok355KxkbCkBJ-AMB3HdT</recordid><startdate>20020301</startdate><enddate>20020301</enddate><creator>Kurogi, J. (Kagoshima Univ. (Japan))</creator><creator>Iida, T</creator><general>The Japanese Society of Fish Pathology</general><scope>FBQ</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20020301</creationdate><title>Inhibitory effect of cortisol on the defense activities of tilapia neutrophils in vitro</title><author>Kurogi, J. (Kagoshima Univ. (Japan)) ; Iida, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-8c44a443c54f7ccc6740b7e1c49c7bcf015592dc483f3cdb16205d6d51d88c2b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>cortisol</topic><topic>DEFENCE MECHANISMS</topic><topic>GLUCOCORTICOIDS</topic><topic>GRANULOCYTES</topic><topic>IN VITRO EXPERIMENTATION</topic><topic>neutrophil activity</topic><topic>OREOCHROMIS NILOTICUS</topic><topic>stress</topic><topic>tilapia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kurogi, J. (Kagoshima Univ. (Japan))</creatorcontrib><creatorcontrib>Iida, T</creatorcontrib><collection>AGRIS</collection><collection>CrossRef</collection><jtitle>Fish Pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kurogi, J. (Kagoshima Univ. (Japan))</au><au>Iida, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inhibitory effect of cortisol on the defense activities of tilapia neutrophils in vitro</atitle><jtitle>Fish Pathology</jtitle><addtitle>Fish Pathol.</addtitle><date>2002-03-01</date><risdate>2002</risdate><volume>37</volume><issue>1</issue><spage>13</spage><epage>16</epage><pages>13-16</pages><issn>0388-788X</issn><eissn>1881-7335</eissn><abstract>On the premise that fish neutrophil activities are depressed under stressed conditions, this study investigated the direct effect of cortisol on the in vitro activity of neutrophiles collected from tilapia Oreochromis niloticus. Neutrophils were obtained from swim bladders and exposed to different levels of cortisol (0-1000 ng/mL), and their chemotactic, phagocytic and respiratory burst activities were assessed. This treatment suppressed neutrophil activities as seen in the reduction of chemotactic, phagocytic and respiratory burst activities. Neutrophil activities appeared to be suppressed in a dose-dependent manner leading to a considerable reduction in neutrophil activities with high concentrations of cortisol. Nevertheless, we showed that the respiratory burst activity was able to recover from the observed effect after cortisol was removed. The results in this study strongly suggest that cortisol has a directly adverse effect on fish neutrophil defense activities, but that the effect is reversible.</abstract><pub>The Japanese Society of Fish Pathology</pub><doi>10.3147/jsfp.37.13</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0388-788X |
| ispartof | Fish Pathology, 2002/03/15, Vol.37(1), pp.13-16 |
| issn | 0388-788X 1881-7335 |
| language | eng |
| recordid | cdi_crossref_primary_10_3147_jsfp_37_13 |
| source | EZB Electronic Journals Library |
| subjects | cortisol DEFENCE MECHANISMS GLUCOCORTICOIDS GRANULOCYTES IN VITRO EXPERIMENTATION neutrophil activity OREOCHROMIS NILOTICUS stress tilapia |
| title | Inhibitory effect of cortisol on the defense activities of tilapia neutrophils in vitro |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T17%3A41%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-fao_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Inhibitory%20effect%20of%20cortisol%20on%20the%20defense%20activities%20of%20tilapia%20neutrophils%20in%20vitro&rft.jtitle=Fish%20Pathology&rft.au=Kurogi,%20J.%20(Kagoshima%20Univ.%20(Japan))&rft.date=2002-03-01&rft.volume=37&rft.issue=1&rft.spage=13&rft.epage=16&rft.pages=13-16&rft.issn=0388-788X&rft.eissn=1881-7335&rft_id=info:doi/10.3147/jsfp.37.13&rft_dat=%3Cfao_cross%3EJP2002003387%3C/fao_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |