Cost-effectiveness analysis of solifenacin versus oxybutynin immediate-release in the treatment of patients with overactive bladder in the United Kingdom

Abstract Objective: To carry out a cost-utility analysis comparing initial treatment with solifenacin 5 mg/day vs oxybutynin immediate-release (IR) 15 mg/day for the treatment of patients with overactive bladder (OAB) from the perspective of the UK National Health Service (NHS). Methods: A Markov mo...

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Veröffentlicht in:	Journal of medical economics 2013-10, Vol.16 (10), p.1246-1254
Hauptverfasser:	Hart, Warren Mark, Abrams, Paul, Munro, Vicki, Retsa, Peny, Nazir, Jameel
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzhydryl Compounds - administration & dosage Benzhydryl Compounds - adverse effects Benzhydryl Compounds - economics Cohort Studies Cost Cost-Benefit Analysis Cresols - administration & dosage Cresols - adverse effects Cresols - economics Humans Incontinence Pads - economics Incontinence Pads - statistics & numerical data Mandelic Acids - administration & dosage Mandelic Acids - adverse effects Mandelic Acids - economics Markov Chains Medication Adherence - statistics & numerical data Models, Economic Muscarinic Antagonists - administration & dosage Muscarinic Antagonists - adverse effects Muscarinic Antagonists - economics Overactive bladder Oxybutynin Patient Dropouts - statistics & numerical data Phenylpropanolamine - administration & dosage Phenylpropanolamine - adverse effects Phenylpropanolamine - economics Quality-Adjusted Life Years Quinuclidines - administration & dosage Quinuclidines - adverse effects Quinuclidines - economics Solifenacin Solifenacin Succinate Tetrahydroisoquinolines - administration & dosage Tetrahydroisoquinolines - adverse effects Tetrahydroisoquinolines - economics Tolterodine Tartrate Treatment Outcome United Kingdom Urinary Bladder, Overactive - complications Urinary Bladder, Overactive - drug therapy Urinary Bladder, Overactive - economics Urinary Incontinence - drug therapy Urinary Incontinence - economics Urinary Incontinence - etiology Utility
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