The Penetration of Lincomycin into Normal Human Bone: Determinations of Penetration into Compact Bone, Spongy Bone and Bone Marrow
The penetration of lincomycin into normal bone was studied in 10 patients with fracture of the neck of the femur, a separate determination being made of the lincomycin concentration in serum, bone marrow, spongy bone and compact bone. The concentration of lincomycin in bone marrow was found to be at...
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| Veröffentlicht in: | Acta orthopaedica 1976, Vol.47 (3), p.267-270 |
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| container_end_page | 270 |
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| container_issue | 3 |
| container_start_page | 267 |
| container_title | Acta orthopaedica |
| container_volume | 47 |
| creator | Nielsen, M. Lykkegaard Hansen, I. Nielsen, J. Boss |
| description | The penetration of lincomycin into normal bone was studied in 10 patients with fracture of the neck of the femur, a separate determination being made of the lincomycin concentration in serum, bone marrow, spongy bone and compact bone. The concentration of lincomycin in bone marrow was found to be at the same level as that in the serum. The concentration in spongy bone amounted in most cases to 50 to 75 per cent of the concentration in the serum, whereas the concentration in compact bone varied from 0 to 15 per cent of that in the serum. |
| doi_str_mv | 10.3109/17453677608991989 |
| format | Article |
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The concentration in spongy bone amounted in most cases to 50 to 75 per cent of the concentration in the serum, whereas the concentration in compact bone varied from 0 to 15 per cent of that in the serum.</description><identifier>ISSN: 1745-3674</identifier><identifier>ISSN: 0001-6470</identifier><identifier>EISSN: 1745-3682</identifier><identifier>DOI: 10.3109/17453677608991989</identifier><language>eng</language><publisher>Informa UK Ltd</publisher><subject>bone marrow ; bone tissue ; compact bone ; lincomycin ; spongy bone</subject><ispartof>Acta orthopaedica, 1976, Vol.47 (3), p.267-270</ispartof><rights>1976 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1976</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c348t-4f056a5404fcc56d8755255d1dfbe3cbbbc8de0fa41db12e6f5d96111637728c3</citedby><cites>FETCH-LOGICAL-c348t-4f056a5404fcc56d8755255d1dfbe3cbbbc8de0fa41db12e6f5d96111637728c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids></links><search><creatorcontrib>Nielsen, M. Lykkegaard</creatorcontrib><creatorcontrib>Hansen, I.</creatorcontrib><creatorcontrib>Nielsen, J. Boss</creatorcontrib><title>The Penetration of Lincomycin into Normal Human Bone: Determinations of Penetration into Compact Bone, Spongy Bone and Bone Marrow</title><title>Acta orthopaedica</title><description>The penetration of lincomycin into normal bone was studied in 10 patients with fracture of the neck of the femur, a separate determination being made of the lincomycin concentration in serum, bone marrow, spongy bone and compact bone. The concentration of lincomycin in bone marrow was found to be at the same level as that in the serum. The concentration in spongy bone amounted in most cases to 50 to 75 per cent of the concentration in the serum, whereas the concentration in compact bone varied from 0 to 15 per cent of that in the serum.</description><subject>bone marrow</subject><subject>bone tissue</subject><subject>compact bone</subject><subject>lincomycin</subject><subject>spongy bone</subject><issn>1745-3674</issn><issn>0001-6470</issn><issn>1745-3682</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><recordid>eNp90FtLwzAUB_AgCs7pB_AtH8Bp0lzaqi86LxPmBZzPJc3FRdpkpBmjr35y105EEX3KyYHfOZw_AIcYHROM8hOcUkZ4mnKU5TnOs3wLDLreiPAs2f6qU7oL9prmDSGS0RwNwPtsruGTdjoGEa130Bs4tU76upXWQeuihw8-1KKCk2UtHLz0Tp_CKx11qK3rTdOh7zN6Nfb1QsjYgyP4vPDute0_UDi1Ke5FCH61D3aMqBp98PkOwcvN9Ww8GU0fb-_GF9ORJDSLI2oQ44JRRI2UjKssZSxhTGFlSk1kWZYyUxoZQbEqcaK5YSrnGGNO0jTJJBkCvJkrg2-aoE2xCLYWoS0wKroQi18hrs35xlhnuhRWPlSqiKKtfDBBOGmbjv7Nz37wuRZVnEsRdPHml8Gtz_1n-QfN-IwG</recordid><startdate>1976</startdate><enddate>1976</enddate><creator>Nielsen, M. Lykkegaard</creator><creator>Hansen, I.</creator><creator>Nielsen, J. Boss</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1976</creationdate><title>The Penetration of Lincomycin into Normal Human Bone: Determinations of Penetration into Compact Bone, Spongy Bone and Bone Marrow</title><author>Nielsen, M. Lykkegaard ; Hansen, I. ; Nielsen, J. Boss</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c348t-4f056a5404fcc56d8755255d1dfbe3cbbbc8de0fa41db12e6f5d96111637728c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>bone marrow</topic><topic>bone tissue</topic><topic>compact bone</topic><topic>lincomycin</topic><topic>spongy bone</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nielsen, M. Lykkegaard</creatorcontrib><creatorcontrib>Hansen, I.</creatorcontrib><creatorcontrib>Nielsen, J. Boss</creatorcontrib><collection>CrossRef</collection><jtitle>Acta orthopaedica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nielsen, M. Lykkegaard</au><au>Hansen, I.</au><au>Nielsen, J. Boss</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Penetration of Lincomycin into Normal Human Bone: Determinations of Penetration into Compact Bone, Spongy Bone and Bone Marrow</atitle><jtitle>Acta orthopaedica</jtitle><date>1976</date><risdate>1976</risdate><volume>47</volume><issue>3</issue><spage>267</spage><epage>270</epage><pages>267-270</pages><issn>1745-3674</issn><issn>0001-6470</issn><eissn>1745-3682</eissn><abstract>The penetration of lincomycin into normal bone was studied in 10 patients with fracture of the neck of the femur, a separate determination being made of the lincomycin concentration in serum, bone marrow, spongy bone and compact bone. The concentration of lincomycin in bone marrow was found to be at the same level as that in the serum. The concentration in spongy bone amounted in most cases to 50 to 75 per cent of the concentration in the serum, whereas the concentration in compact bone varied from 0 to 15 per cent of that in the serum.</abstract><pub>Informa UK Ltd</pub><doi>10.3109/17453677608991989</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1745-3674 |
| ispartof | Acta orthopaedica, 1976, Vol.47 (3), p.267-270 |
| issn | 1745-3674 0001-6470 1745-3682 |
| language | eng |
| recordid | cdi_crossref_primary_10_3109_17453677608991989 |
| source | EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | bone marrow bone tissue compact bone lincomycin spongy bone |
| title | The Penetration of Lincomycin into Normal Human Bone: Determinations of Penetration into Compact Bone, Spongy Bone and Bone Marrow |
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