Placental Weights of Normal and Aneuploid Early Human Fetuses
Placental and body weights were plotted for 252 normal human fetuses less than 600 gm and mean regressions and 95% prediction intervals were calculated. Placentas from 62 aneuploid fetuses were compared to these standards. Placenta to body weight ratios from 34 trisomy-21 fetuses were not reduced bu...
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| Veröffentlicht in: | Fetal and pediatric pathology 1989, Vol.9 (4), p.425-431 |
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| container_title | Fetal and pediatric pathology |
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| creator | Shepard, Thomas H. Fitzsimmons, Jack M. Fantel, Alan G. Pascoe-Mason, Julie |
| description | Placental and body weights were plotted for 252 normal human fetuses less than 600 gm and mean regressions and 95% prediction intervals were calculated. Placentas from 62 aneuploid fetuses were compared to these standards. Placenta to body weight ratios from 34 trisomy-21 fetuses were not reduced but those from 15 trisomy-18 fetuses were generally decreased. One of 5 trisomy-13 ratios was below the prediction interval. Among 7 triploid fetuses the ratios were above the normal interval in 3 and below normal in 4. Three of the triploids that were below were associated with a karyotype of 69, XXX and did not have hydatidiform degeneration. All 4 placentas with hydatidiform changes were abnormally large. All of the 7 triploids had 3-4 syndactyly and 3 had hydrocephalus. |
| doi_str_mv | 10.3109/15513818909022363 |
| format | Article |
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Placentas from 62 aneuploid fetuses were compared to these standards. Placenta to body weight ratios from 34 trisomy-21 fetuses were not reduced but those from 15 trisomy-18 fetuses were generally decreased. One of 5 trisomy-13 ratios was below the prediction interval. Among 7 triploid fetuses the ratios were above the normal interval in 3 and below normal in 4. Three of the triploids that were below were associated with a karyotype of 69, XXX and did not have hydatidiform degeneration. All 4 placentas with hydatidiform changes were abnormally large. 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Placentas from 62 aneuploid fetuses were compared to these standards. Placenta to body weight ratios from 34 trisomy-21 fetuses were not reduced but those from 15 trisomy-18 fetuses were generally decreased. One of 5 trisomy-13 ratios was below the prediction interval. Among 7 triploid fetuses the ratios were above the normal interval in 3 and below normal in 4. Three of the triploids that were below were associated with a karyotype of 69, XXX and did not have hydatidiform degeneration. All 4 placentas with hydatidiform changes were abnormally large. All of the 7 triploids had 3-4 syndactyly and 3 had hydrocephalus.</description><subject>Aneuploidy</subject><subject>Chromosome Aberrations</subject><subject>Chromosome Disorders</subject><subject>Female</subject><subject>Fetus - cytology</subject><subject>Humans</subject><subject>Karyotyping</subject><subject>Male</subject><subject>Organ Size</subject><subject>Placenta - anatomy & histology</subject><subject>placental weight</subject><subject>Sex Chromosome Aberrations</subject><subject>Statistics as Topic</subject><subject>triploidy</subject><subject>trisomy</subject><issn>1551-3815</issn><issn>0277-0938</issn><issn>1551-3823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9Lw0AQxRdRqlY_gAchJ2_R_Zdkg3oopbVCUQ-Kx7DdnbUpm2zdTZB-exNaCiJ6mRnezHsMP4QuCL5mBOc3JEkIE0TkOMeUspQdoJNei5mg7HA_k-QYnYawwphlQmQDNKBZLmgqTtD9i5UK6kba6B3Kj2UTImeiJ-erTpG1jkY1tGvrSh1NpLebaNZWso6m0LQBwhk6MtIGON_1IXqbTl7Hs3j-_PA4Hs1jxUjaxIprpnIDqdYSA024yQQIrrkUGDQTC9wVyhMjVMqk4HkqxSJhedaNPNOYDdHVNnft3WcLoSmqMiiwVtbg2lBkOeUiEaQ7JNtD5V0IHkyx9mUl_aYguOiRFb-QdZ7LXXi7qEDvHTtG3f5uuy9r03P5ct7qopEb67zxslZl6KP_jr_9YV-CtM1SSQ_FyrW-7rj989w3gH-Keg</recordid><startdate>1989</startdate><enddate>1989</enddate><creator>Shepard, Thomas H.</creator><creator>Fitzsimmons, Jack M.</creator><creator>Fantel, Alan G.</creator><creator>Pascoe-Mason, Julie</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1989</creationdate><title>Placental Weights of Normal and Aneuploid Early Human Fetuses</title><author>Shepard, Thomas H. ; Fitzsimmons, Jack M. ; Fantel, Alan G. ; Pascoe-Mason, Julie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-c4d3c9fe6dda0e254f78e84d4a80ed38b0d38245f8c63a8496a8b539784947d03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Aneuploidy</topic><topic>Chromosome Aberrations</topic><topic>Chromosome Disorders</topic><topic>Female</topic><topic>Fetus - cytology</topic><topic>Humans</topic><topic>Karyotyping</topic><topic>Male</topic><topic>Organ Size</topic><topic>Placenta - anatomy & histology</topic><topic>placental weight</topic><topic>Sex Chromosome Aberrations</topic><topic>Statistics as Topic</topic><topic>triploidy</topic><topic>trisomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shepard, Thomas H.</creatorcontrib><creatorcontrib>Fitzsimmons, Jack M.</creatorcontrib><creatorcontrib>Fantel, Alan G.</creatorcontrib><creatorcontrib>Pascoe-Mason, Julie</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fetal and pediatric pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shepard, Thomas H.</au><au>Fitzsimmons, Jack M.</au><au>Fantel, Alan G.</au><au>Pascoe-Mason, Julie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Placental Weights of Normal and Aneuploid Early Human Fetuses</atitle><jtitle>Fetal and pediatric pathology</jtitle><addtitle>Pediatr Pathol</addtitle><date>1989</date><risdate>1989</risdate><volume>9</volume><issue>4</issue><spage>425</spage><epage>431</epage><pages>425-431</pages><issn>1551-3815</issn><issn>0277-0938</issn><eissn>1551-3823</eissn><abstract>Placental and body weights were plotted for 252 normal human fetuses less than 600 gm and mean regressions and 95% prediction intervals were calculated. Placentas from 62 aneuploid fetuses were compared to these standards. Placenta to body weight ratios from 34 trisomy-21 fetuses were not reduced but those from 15 trisomy-18 fetuses were generally decreased. One of 5 trisomy-13 ratios was below the prediction interval. Among 7 triploid fetuses the ratios were above the normal interval in 3 and below normal in 4. Three of the triploids that were below were associated with a karyotype of 69, XXX and did not have hydatidiform degeneration. All 4 placentas with hydatidiform changes were abnormally large. All of the 7 triploids had 3-4 syndactyly and 3 had hydrocephalus.</abstract><cop>United States</cop><pub>Informa UK Ltd</pub><pmid>2798268</pmid><doi>10.3109/15513818909022363</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1551-3815 |
| ispartof | Fetal and pediatric pathology, 1989, Vol.9 (4), p.425-431 |
| issn | 1551-3815 0277-0938 1551-3823 |
| language | eng |
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| source | Taylor & Francis Online; MEDLINE; Taylor & Francis Medical Library - CRKN |
| subjects | Aneuploidy Chromosome Aberrations Chromosome Disorders Female Fetus - cytology Humans Karyotyping Male Organ Size Placenta - anatomy & histology placental weight Sex Chromosome Aberrations Statistics as Topic triploidy trisomy |
| title | Placental Weights of Normal and Aneuploid Early Human Fetuses |
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