Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects

In this study, 4-(2-substituted hydrazinyl)benzenesulfonamides were synthesized by microwave irradiation and their chemical structures were confirmed by 1 H NMR, 13 CNMR, and HRMS. Ketones used were: Acetophenone (S1), 4-methylacetophenone (S2), 4-chloroacetophenone (S3), 4-fluoroacetophenone (S4),...

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Veröffentlicht in:	Journal of enzyme inhibition and medicinal chemistry 2016-07, Vol.31 (4), p.568-573
Hauptverfasser:	Gul, Halise Inci, Kucukoglu, Kaan, Yamali, Cem, Bilginer, Sinan, Yuca, Hafize, Ozturk, Iknur, Taslimi, Parham, Gulcin, Ilhami, Supuran, Claudiu T.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Acethylfuran 2-acethylthiophene acetophenones Benzenesulfonamides carbonic anhydrase Carbonic Anhydrase I - antagonists & inhibitors Carbonic Anhydrase I - metabolism Carbonic Anhydrase II - antagonists & inhibitors Carbonic Anhydrase II - metabolism Carbonic Anhydrase Inhibitors - chemical synthesis Carbonic Anhydrase Inhibitors - chemistry Carbonic Anhydrase Inhibitors - pharmacology Dose-Response Relationship, Drug enzyme inhibition Humans indanone Molecular Structure Structure-Activity Relationship sulfonamide Sulfonamides - chemical synthesis Sulfonamides - chemistry Sulfonamides - pharmacology
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