Anti-inflammatory, analgesic and antioxidant activities of 3,4-oxo-isopropylidene-shikimic acid

Context 3,4-Oxo-isopropylidene-shikimic acid (ISA) is an analog of shikimic acid (SA). SA is extracted from the dry fruit of Illicium verum Hook. f. (Magnoliaceae), which has been used for treating stomachaches, skin inflammation and rheumatic pain. Objective To investigate the anti-inflammatory, an...

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Veröffentlicht in:	Pharmaceutical biology 2016-10, Vol.54 (10), p.2282-2287
Hauptverfasser:	Sun, Jin-Yao, You, Cui-Yu, Dong, Kai, You, Hai-Sheng, Xing, Jian-Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid Analgesics - pharmacology Animals Anti-Inflammatory Agents - pharmacology Antioxidants - pharmacology Carrageenan Cotton Fiber Dinoprostone - metabolism Disease Models, Animal Dose-Response Relationship, Drug Edema - chemically induced Edema - metabolism Edema - prevention & control Female Granuloma, Foreign-Body - chemically induced Granuloma, Foreign-Body - prevention & control Hot Temperature Hydroxyl Radical - chemistry Illicium verum Hook.f Indomethacin - pharmacology Male malondialdehyde Malondialdehyde - metabolism Mice, Inbred ICR Pain - etiology Pain - prevention & control prostaglandin E2 Rats, Sprague-Dawley Shikimic Acid - analogs & derivatives Shikimic Acid - pharmacology Superoxides - chemistry Time Factors xylene Xylenes
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