Experimental Cryosurgery of the Liver Under Magnetic Resonance Guidance
The feasibility and the advantages of magnetic resonance (MR)-guided interstitial cryosurgery of the liver in an 0.5 Tesla open MR system have been evaluated. Cryosurgery was performed using an Erbocryo PS system with a nonmagnetic cryoprobe of 6 mm diameter. The probe was inserted into the liver pa...
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| Veröffentlicht in: | Computer aided surgery (New York, N.Y.) N.Y.), 1997, Vol.2 (6), p.340-345 |
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| creator | Klotz, H. P. Flury, R. Schönenberger, A. Debatin, J. F. Uhlschmid, G. Largiadèr, F. |
| description | The feasibility and the advantages of magnetic resonance (MR)-guided interstitial cryosurgery of the liver in an 0.5 Tesla open MR system have been evaluated. Cryosurgery was performed using an Erbocryo PS system with a nonmagnetic cryoprobe of 6 mm diameter. The probe was inserted into the liver parenchyma under real-time MR control. Using continuous MR imaging two freezing cycles of 12 min each were applied. After conventional and dynamic gadolinium-enhanced MR imaging, the animals were sacrificed after 30 min, 3 hr, 24 hr, 7 days, and 21 days. Each lesion was analyzed using light microscopy.
A total of seven cryolesions were made in five animals without any complications from cryosurgery. During real-time imaging, cryolesions appeared as a hemispherical growing signal loss with a mean volume of 16.4 cm3. Macroscopic volumes of the lesions showed a good correlation with dynamic enhanced MR images during follow-up, whereas real-time images usually showed an underestimation of the lesion volumes. Cryosurgery of the liver in an open-configuration MR system is a feasible and safe method. MR imaging allows the guidance and the follow-up of cryolesions of the liver with good. |
| doi_str_mv | 10.3109/10929089709149834 |
| format | Article |
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A total of seven cryolesions were made in five animals without any complications from cryosurgery. During real-time imaging, cryolesions appeared as a hemispherical growing signal loss with a mean volume of 16.4 cm3. Macroscopic volumes of the lesions showed a good correlation with dynamic enhanced MR images during follow-up, whereas real-time images usually showed an underestimation of the lesion volumes. Cryosurgery of the liver in an open-configuration MR system is a feasible and safe method. MR imaging allows the guidance and the follow-up of cryolesions of the liver with good.</description><identifier>ISSN: 1092-9088</identifier><identifier>EISSN: 1097-0150</identifier><identifier>DOI: 10.3109/10929089709149834</identifier><identifier>PMID: 9587696</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Animals ; Cryosurgery - instrumentation ; Feasibility Studies ; Female ; Image Processing, Computer-Assisted - instrumentation ; interstitial cryosurgery of the liver ; Liver - pathology ; Liver - surgery ; liver metastases ; magnetic resonance imaging ; Magnetic Resonance Imaging - instrumentation ; open-configuration magnetic resonance system ; Swine</subject><ispartof>Computer aided surgery (New York, N.Y.), 1997, Vol.2 (6), p.340-345</ispartof><rights>1997 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1997</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2914-272dcefc113ef33b42caf719ed773cc946a00f5c6f04a3794209f71ef4dcbb573</citedby><cites>FETCH-LOGICAL-c2914-272dcefc113ef33b42caf719ed773cc946a00f5c6f04a3794209f71ef4dcbb573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9587696$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Klotz, H. P.</creatorcontrib><creatorcontrib>Flury, R.</creatorcontrib><creatorcontrib>Schönenberger, A.</creatorcontrib><creatorcontrib>Debatin, J. F.</creatorcontrib><creatorcontrib>Uhlschmid, G.</creatorcontrib><creatorcontrib>Largiadèr, F.</creatorcontrib><title>Experimental Cryosurgery of the Liver Under Magnetic Resonance Guidance</title><title>Computer aided surgery (New York, N.Y.)</title><addtitle>Comput Aided Surg</addtitle><description>The feasibility and the advantages of magnetic resonance (MR)-guided interstitial cryosurgery of the liver in an 0.5 Tesla open MR system have been evaluated. Cryosurgery was performed using an Erbocryo PS system with a nonmagnetic cryoprobe of 6 mm diameter. The probe was inserted into the liver parenchyma under real-time MR control. Using continuous MR imaging two freezing cycles of 12 min each were applied. After conventional and dynamic gadolinium-enhanced MR imaging, the animals were sacrificed after 30 min, 3 hr, 24 hr, 7 days, and 21 days. Each lesion was analyzed using light microscopy.
A total of seven cryolesions were made in five animals without any complications from cryosurgery. During real-time imaging, cryolesions appeared as a hemispherical growing signal loss with a mean volume of 16.4 cm3. Macroscopic volumes of the lesions showed a good correlation with dynamic enhanced MR images during follow-up, whereas real-time images usually showed an underestimation of the lesion volumes. Cryosurgery of the liver in an open-configuration MR system is a feasible and safe method. MR imaging allows the guidance and the follow-up of cryolesions of the liver with good.</description><subject>Animals</subject><subject>Cryosurgery - instrumentation</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Image Processing, Computer-Assisted - instrumentation</subject><subject>interstitial cryosurgery of the liver</subject><subject>Liver - pathology</subject><subject>Liver - surgery</subject><subject>liver metastases</subject><subject>magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - instrumentation</subject><subject>open-configuration magnetic resonance system</subject><subject>Swine</subject><issn>1092-9088</issn><issn>1097-0150</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UFtLwzAUDqJMnf4AH4Q--VbNpW0a9EXGnMJEEPdc0vRk6-iSmbRq_72ZG4KIPpycQ74L53wInRF8yQgWV6GowLngWJBE5CzZQ0fhj8eYpHj_a6ZxIOSH6Nj7JcZYZCwfoIFIc56J7AhNxh9rcPUKTCubaOR66zs3B9dHVkftAqJp_QYumpkqvI9ybqCtVfQM3hppFESTrq42wwk60LLxcLrrQzS7G7-M7uPp0-RhdDuNFQ0rxpTTSoFWhDDQjJUJVVJzIqDinCklkkxirFOVaZxIxkVCsQg46KRSZZlyNkQXW9-1s68d-LZY1V5B00gDtvMFF6mgGWGBSLZE5az3DnSxDmdK1xcEF5vwil_hBc35zrwrV1B9K3ZpBfxmi9dGW7eS79Y1VdHKvrFOuxBD7TfWf9tf_5AvQDbtQkkHxdJ2zoTc_lnuE46jj3A</recordid><startdate>1997</startdate><enddate>1997</enddate><creator>Klotz, H. P.</creator><creator>Flury, R.</creator><creator>Schönenberger, A.</creator><creator>Debatin, J. F.</creator><creator>Uhlschmid, G.</creator><creator>Largiadèr, F.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1997</creationdate><title>Experimental Cryosurgery of the Liver Under Magnetic Resonance Guidance</title><author>Klotz, H. P. ; Flury, R. ; Schönenberger, A. ; Debatin, J. F. ; Uhlschmid, G. ; Largiadèr, F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2914-272dcefc113ef33b42caf719ed773cc946a00f5c6f04a3794209f71ef4dcbb573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Animals</topic><topic>Cryosurgery - instrumentation</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Image Processing, Computer-Assisted - instrumentation</topic><topic>interstitial cryosurgery of the liver</topic><topic>Liver - pathology</topic><topic>Liver - surgery</topic><topic>liver metastases</topic><topic>magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - instrumentation</topic><topic>open-configuration magnetic resonance system</topic><topic>Swine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Klotz, H. P.</creatorcontrib><creatorcontrib>Flury, R.</creatorcontrib><creatorcontrib>Schönenberger, A.</creatorcontrib><creatorcontrib>Debatin, J. F.</creatorcontrib><creatorcontrib>Uhlschmid, G.</creatorcontrib><creatorcontrib>Largiadèr, F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Computer aided surgery (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Klotz, H. P.</au><au>Flury, R.</au><au>Schönenberger, A.</au><au>Debatin, J. F.</au><au>Uhlschmid, G.</au><au>Largiadèr, F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Experimental Cryosurgery of the Liver Under Magnetic Resonance Guidance</atitle><jtitle>Computer aided surgery (New York, N.Y.)</jtitle><addtitle>Comput Aided Surg</addtitle><date>1997</date><risdate>1997</risdate><volume>2</volume><issue>6</issue><spage>340</spage><epage>345</epage><pages>340-345</pages><issn>1092-9088</issn><eissn>1097-0150</eissn><abstract>The feasibility and the advantages of magnetic resonance (MR)-guided interstitial cryosurgery of the liver in an 0.5 Tesla open MR system have been evaluated. Cryosurgery was performed using an Erbocryo PS system with a nonmagnetic cryoprobe of 6 mm diameter. The probe was inserted into the liver parenchyma under real-time MR control. Using continuous MR imaging two freezing cycles of 12 min each were applied. After conventional and dynamic gadolinium-enhanced MR imaging, the animals were sacrificed after 30 min, 3 hr, 24 hr, 7 days, and 21 days. Each lesion was analyzed using light microscopy.
A total of seven cryolesions were made in five animals without any complications from cryosurgery. During real-time imaging, cryolesions appeared as a hemispherical growing signal loss with a mean volume of 16.4 cm3. Macroscopic volumes of the lesions showed a good correlation with dynamic enhanced MR images during follow-up, whereas real-time images usually showed an underestimation of the lesion volumes. Cryosurgery of the liver in an open-configuration MR system is a feasible and safe method. MR imaging allows the guidance and the follow-up of cryolesions of the liver with good.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>9587696</pmid><doi>10.3109/10929089709149834</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1092-9088 |
| ispartof | Computer aided surgery (New York, N.Y.), 1997, Vol.2 (6), p.340-345 |
| issn | 1092-9088 1097-0150 |
| language | eng |
| recordid | cdi_crossref_primary_10_3109_10929089709149834 |
| source | MEDLINE; Access via Wiley Online Library; Alma/SFX Local Collection |
| subjects | Animals Cryosurgery - instrumentation Feasibility Studies Female Image Processing, Computer-Assisted - instrumentation interstitial cryosurgery of the liver Liver - pathology Liver - surgery liver metastases magnetic resonance imaging Magnetic Resonance Imaging - instrumentation open-configuration magnetic resonance system Swine |
| title | Experimental Cryosurgery of the Liver Under Magnetic Resonance Guidance |
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