Impact of crystalline form changing on behavior of microcapsules prepared from three-component gel system

In this paper, the effect of anhydrous-monohydrate process-induced transformation of theophylline was examined in microcapsules produced by in situ gelation method using sodium alginate, hydroxypropylmethylcellulose and hydroxyethylcellulose. Films produced from gel were applied to characterize the...

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Veröffentlicht in:	Pharmaceutical development and technology 2010-12, Vol.15 (6), p.553-561
Hauptverfasser:	Fenyvesi, Zsófia, Ashour, Khaled Omaru A., Zelkó, Romána, Müller, Ulrich, Antal, István, Klebovich, Imre, Marton, Sylvia
Format:	Artikel
Sprache:	eng
Schlagworte:	Alginates - chemistry Bronchodilator Agents - administration & dosage Bronchodilator Agents - chemistry Capsules Cellulose - analogs & derivatives Cellulose - chemistry crystalline form Crystallization Gels Glucuronic Acid - chemistry Hexuronic Acids - chemistry hydrophilic polymers Hypromellose Derivatives in situ gelation Methylcellulose - analogs & derivatives Methylcellulose - chemistry microcapsule Models, Chemical Polymers - chemistry Sodium alginate Theophylline - administration & dosage Theophylline - chemistry Water - chemistry
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