Nephrotoxicity of Hemoglobin Solutions

Nephrotoxicity is a problem of hemoglobin solutions (HbS) that still awaits full elucidation and correction. Therefore, a study was conducted using five HbS with different characteristics to replace 1/3 of blood volume in five groups of rabbits. All HbS contained bovine Hb, 6.5 g/dl, dissolved into...

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Veröffentlicht in:	Artificial cells, blood substitutes, and immobilization biotechnology blood substitutes, and immobilization biotechnology, 1990, Vol.18 (2), p.233-249
Hauptverfasser:	Feola, Mario, Simoni, Jan, Tran, Ruc, Canizaro, Peter C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Substitutes - toxicity Cattle Cross-Linking Reagents Endotoxins - isolation & purification Endotoxins - toxicity Hemoglobins - isolation & purification Hemoglobinuria - etiology Hemoglobinuria - prevention & control Hydrogen-Ion Concentration Kidney - drug effects Kidney - pathology Kidney - physiopathology Male Mannitol - pharmacology Phospholipids - isolation & purification Phospholipids - toxicity Rabbits Solutions
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