Buprenorphine Treatment of Opiate and Cocaine Abuse: Clinical and Preclinical Studies

Buprenorphine, an opioid mixed agonist-antagonist, is a potent analgesic that appears to be effective for the treatment of opiate abuse. Recent preclinical studies have shown that buprenorphine also significantly reduces cocaine self-administration by rhesus monkeys for periods up to 120 days. This...

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Veröffentlicht in:	Harvard review of psychiatry 1993-09, Vol.1 (3), p.168-183
Hauptverfasser:	Mello, Nancy K., Mendelson, Jack H., Lukas, Scott E., Gastfriend, David R., Teoh, Siew Koon, Holman, B. Leonard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Buprenorphine - adverse effects Buprenorphine - therapeutic use Clinical Trials as Topic Cocaine-Related Disorders - psychology Cocaine-Related Disorders - rehabilitation Drug Evaluation, Preclinical Drug Interactions Humans Macaca mulatta Opioid-Related Disorders - psychology Opioid-Related Disorders - rehabilitation Treatment Outcome
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