Major Histocompatibility Complex (MHC) Factors Predisposing to and Protecting Against Graves' Eye Disease

We investigated the influence of gene mapping within the major histocompatibility complex on the susceptibility to Graves' eye disease. We studied 133 randomly selected patients with Graves' disease, many of whom had eye disease. HLA B8 and DR3 carried the greatest risk for disease but the...

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Veröffentlicht in:	Autoimmunity (Chur, Switzerland) Switzerland), 1988, Vol.1 (4), p.307-315
Hauptverfasser:	Frecker, Maxine, Mercer, Gregory, Skanes, Verna M., Farid, Nadir R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Disease Susceptibility - immunology Eye Diseases - etiology Eye Diseases - immunology Female Graves Disease - complications Graves Disease - immunology Graves' eye disease Haplotypes HLA Antigens - analysis Humans Male MHC Newfoundland and Labrador Odds Ratio
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