Mild step-down heating causes increased levels of HSP68 and of HSP84 mRNA and enhances thermotolerance

Mammalian cells exhibit increased sensitivity to hyperthermic temperatures of 38-42°C after an acute high-temperature heat shock; this phenomenon is known as thermosensitization or the step-down heating effect. In order to determine whether the increase of heat shock mRNA after heat stress can be th...

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Veröffentlicht in:	International journal of hyperthermia 1994, Vol.10 (1), p.115-125
Hauptverfasser:	van Wijk, R., Ovelgönne, J. H., de Koning, E., Jaarsveld, K., van Rijn, J., Wiegant, F. A. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Survival Effects of various physical factors on living matter (vibrations, electric field, ultrasound, sound...) Fundamental and applied biological sciences. Psychology Heat-Shock Proteins - genetics Hot Temperature HSP mRNA Hyperthermia, Induced - methods Liver Neoplasms, Experimental - genetics Liver Neoplasms, Experimental - metabolism Liver Neoplasms, Experimental - therapy Rats RNA, Messenger - genetics RNA, Messenger - metabolism step-down heating thermosensitization thermotolerance Tissues, organs and organisms biophysics Tumor Cells, Cultured - metabolism
Online-Zugang:	Volltext
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