A new approach to encapsulating nonsteroidal anti-inflammatory drugs. I. Bioavailability and gastric ulcerogenic activity

Abstract Different classes of nonsteroidal anti-inflammatory drugs, NSAIDs, were separately coated with cationic (E) and anionic (L) Eudragit using the fluidized bed technique. The bioavailability and ulcerogenic activity of coated and uncoated drugs were assessed in rats. The cationic coat decrease...

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Veröffentlicht in:	Journal of microencapsulation 1987, Vol.4 (2), p.133-140
Hauptverfasser:	Meshali, M. M., El-Dien, E. Z., Omar, S. A., Luzzi, L. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - adverse effects Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics Biological and medical sciences Biological Availability Capsules General pharmacology Male Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Rats Stomach Ulcer - chemically induced
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