Effect of Corticosteroids on Lung Volume-Pressure Curves in Bleomycin-Induced Lung Injury in the Rat

In this study we investigated changes in volume-pressure curves at various stages after bleomycin induced lung injury (6 h, and 3, 7, and 28 days) and tested the ability of steroids to influence these changes. The most significant decreases in volume-pressure curves were observed at 3 days post bleo...

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Veröffentlicht in:	Experimental lung research 1988, Vol.14 (2), p.183-195
Hauptverfasser:	Grunze, Martin F., Parkinson, Debra, Sulavik, Stephen B., Thrall, Roger S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - pharmacology Adrenal Cortex Hormones - therapeutic use Animals Bleomycin Bronchoalveolar Lavage Fluid - cytology Dexamethasone - therapeutic use Disease Models, Animal Inflammation - drug therapy Inflammation - physiopathology Lung Volume Measurements Male Methylprednisolone - therapeutic use Pulmonary Fibrosis - chemically induced Pulmonary Fibrosis - physiopathology Rats Rats, Inbred F344 Respiratory Distress Syndrome, Adult
Online-Zugang:	Volltext
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