Steroidogenesis in the Two Enriched-Leydig Cell Populations of Human Testis: Evidence for a Positive Control by Seminiferous Tubules Secreted Factor(S)

In two different enriched populations of Leydig cells (called Ff and FII) obtained from human testes (young patients: mean age 36 ± 3 years, n = 6; aged men: mean age 73 ± 2 years, n = 5), the dehydroepiandrosterone and testosterone in vitro outputs were increased in a dose- and time-related manners...

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Veröffentlicht in:	Archives of andrology 1994, Vol.33 (3), p.187-199
Hauptverfasser:	Maillard, N., Wolczynski, S., Argyriou, A., Drosdowsky, M. A., Foucault, P., Carreau, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Biological Factors - physiology Culture Techniques Dehydroepiandrosterone - biosynthesis Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation human Humans Leydig cell populations Leydig Cells - metabolism Male Mammalian male genital system paracrine control secretion seminiferous tubules Seminiferous Tubules - metabolism steroidogenesis testis Testosterone - biosynthesis Vertebrates: reproduction
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