Disposition of α-[(dimethylamino)methyl]-2-(3-ethyl-5-methyl-4-isoxazolyl)-1H-indole-3- methanol (59-801), a hypoglycaemic agent, in rats, dogs and monkeys

1. The disposition of α-[(dimethylamino)methyl]-2-(3-ethyl-5-methyl-4-isoxazolyl)-1 H-[3-14C]indole-3-methanol, an oral hypoglycaemic drug, has been studied in the rat, dog and monkey. 2. Oral doses of the drug were almost completely absorbed. The rate of absorption was rapid in the rat but less rap...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Xenobiotica 1987, Vol.17 (6), p.741-749
Hauptverfasser:	Tse, F. L. S., Orwig, B., Jaffe, J. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences General and cellular metabolism. Vitamins Medical sciences Pharmacology. Drug treatments
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!