Crohn's Disease: Treatment and Outcome

Two hundred and fourteen patients with Crohn's disease (CD) were observed for a mean of 9 years. Colonic CD was diagnosed in 25%, small-bowel CD in 17.5%, and ileocolic CD in 57% of the patients. The cumulative operation rates at 10 years were 47%, 58%, and 71%, respectively. Patients with isol...

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Veröffentlicht in:Scandinavian journal of gastroenterology 1985-01, Vol.20 (8), p.1014-1018
Hauptverfasser: Lind, E., Fausa, O., Gjone, E., Mogensen, S. B.
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container_end_page 1018
container_issue 8
container_start_page 1014
container_title Scandinavian journal of gastroenterology
container_volume 20
creator Lind, E.
Fausa, O.
Gjone, E.
Mogensen, S. B.
description Two hundred and fourteen patients with Crohn's disease (CD) were observed for a mean of 9 years. Colonic CD was diagnosed in 25%, small-bowel CD in 17.5%, and ileocolic CD in 57% of the patients. The cumulative operation rates at 10 years were 47%, 58%, and 71%, respectively. Patients with isolated colonic CD were operated on later in the course of their illness than others (p < 0.05 at 10 years). More than 50% of the patients remained in the 'well being' group regardless of the duration and localization of the disease. The quality of life was better in the non-operated than in the operated group of patients (p < 0.02). Large-bowel carcinomas occurred in three patients. Of six deaths related to CD, two were caused by cancer and three by renal failure due to amyloidosis. The total number of deaths was 3.6 times that expected.
doi_str_mv 10.3109/00365528509088864
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B.</creatorcontrib><title>Crohn's Disease: Treatment and Outcome</title><title>Scandinavian journal of gastroenterology</title><addtitle>Scand J Gastroenterol</addtitle><description>Two hundred and fourteen patients with Crohn's disease (CD) were observed for a mean of 9 years. Colonic CD was diagnosed in 25%, small-bowel CD in 17.5%, and ileocolic CD in 57% of the patients. The cumulative operation rates at 10 years were 47%, 58%, and 71%, respectively. Patients with isolated colonic CD were operated on later in the course of their illness than others (p &lt; 0.05 at 10 years). More than 50% of the patients remained in the 'well being' group regardless of the duration and localization of the disease. The quality of life was better in the non-operated than in the operated group of patients (p &lt; 0.02). Large-bowel carcinomas occurred in three patients. Of six deaths related to CD, two were caused by cancer and three by renal failure due to amyloidosis. The total number of deaths was 3.6 times that expected.</description><subject>Amyloidosis</subject><subject>Amyloidosis - complications</subject><subject>Biological and medical sciences</subject><subject>cancer</subject><subject>clinical study</subject><subject>Crohn Disease - complications</subject><subject>Crohn Disease - mortality</subject><subject>Crohn Disease - surgery</subject><subject>Crohn's disease</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Intestinal Neoplasms - complications</subject><subject>intestinal resection</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Other diseases. Semiology</subject><subject>Prognosis</subject><subject>Quality of Life</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. 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Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lind, E.</creatorcontrib><creatorcontrib>Fausa, O.</creatorcontrib><creatorcontrib>Gjone, E.</creatorcontrib><creatorcontrib>Mogensen, S. B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lind, E.</au><au>Fausa, O.</au><au>Gjone, E.</au><au>Mogensen, S. B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Crohn's Disease: Treatment and Outcome</atitle><jtitle>Scandinavian journal of gastroenterology</jtitle><addtitle>Scand J Gastroenterol</addtitle><date>1985-01-01</date><risdate>1985</risdate><volume>20</volume><issue>8</issue><spage>1014</spage><epage>1018</epage><pages>1014-1018</pages><issn>0036-5521</issn><eissn>1502-7708</eissn><coden>SJGRA4</coden><abstract>Two hundred and fourteen patients with Crohn's disease (CD) were observed for a mean of 9 years. Colonic CD was diagnosed in 25%, small-bowel CD in 17.5%, and ileocolic CD in 57% of the patients. The cumulative operation rates at 10 years were 47%, 58%, and 71%, respectively. Patients with isolated colonic CD were operated on later in the course of their illness than others (p &lt; 0.05 at 10 years). More than 50% of the patients remained in the 'well being' group regardless of the duration and localization of the disease. The quality of life was better in the non-operated than in the operated group of patients (p &lt; 0.02). Large-bowel carcinomas occurred in three patients. Of six deaths related to CD, two were caused by cancer and three by renal failure due to amyloidosis. The total number of deaths was 3.6 times that expected.</abstract><cop>Copenhagen</cop><cop>Oslo</cop><cop>Stockholm</cop><pub>Informa UK Ltd</pub><pmid>4081626</pmid><doi>10.3109/00365528509088864</doi><tpages>5</tpages></addata></record>
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source MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete
subjects Amyloidosis
Amyloidosis - complications
Biological and medical sciences
cancer
clinical study
Crohn Disease - complications
Crohn Disease - mortality
Crohn Disease - surgery
Crohn's disease
Female
Follow-Up Studies
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Intestinal Neoplasms - complications
intestinal resection
Male
Medical sciences
Other diseases. Semiology
Prognosis
Quality of Life
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
title Crohn's Disease: Treatment and Outcome
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