Crohn's Disease: Treatment and Outcome
Two hundred and fourteen patients with Crohn's disease (CD) were observed for a mean of 9 years. Colonic CD was diagnosed in 25%, small-bowel CD in 17.5%, and ileocolic CD in 57% of the patients. The cumulative operation rates at 10 years were 47%, 58%, and 71%, respectively. Patients with isol...
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Veröffentlicht in: | Scandinavian journal of gastroenterology 1985-01, Vol.20 (8), p.1014-1018 |
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creator | Lind, E. Fausa, O. Gjone, E. Mogensen, S. B. |
description | Two hundred and fourteen patients with Crohn's disease (CD) were observed for a mean of 9 years. Colonic CD was diagnosed in 25%, small-bowel CD in 17.5%, and ileocolic CD in 57% of the patients. The cumulative operation rates at 10 years were 47%, 58%, and 71%, respectively. Patients with isolated colonic CD were operated on later in the course of their illness than others (p < 0.05 at 10 years). More than 50% of the patients remained in the 'well being' group regardless of the duration and localization of the disease. The quality of life was better in the non-operated than in the operated group of patients (p < 0.02). Large-bowel carcinomas occurred in three patients. Of six deaths related to CD, two were caused by cancer and three by renal failure due to amyloidosis. The total number of deaths was 3.6 times that expected. |
doi_str_mv | 10.3109/00365528509088864 |
format | Article |
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B.</creator><creatorcontrib>Lind, E. ; Fausa, O. ; Gjone, E. ; Mogensen, S. B.</creatorcontrib><description>Two hundred and fourteen patients with Crohn's disease (CD) were observed for a mean of 9 years. Colonic CD was diagnosed in 25%, small-bowel CD in 17.5%, and ileocolic CD in 57% of the patients. The cumulative operation rates at 10 years were 47%, 58%, and 71%, respectively. Patients with isolated colonic CD were operated on later in the course of their illness than others (p < 0.05 at 10 years). More than 50% of the patients remained in the 'well being' group regardless of the duration and localization of the disease. The quality of life was better in the non-operated than in the operated group of patients (p < 0.02). Large-bowel carcinomas occurred in three patients. Of six deaths related to CD, two were caused by cancer and three by renal failure due to amyloidosis. The total number of deaths was 3.6 times that expected.</description><identifier>ISSN: 0036-5521</identifier><identifier>EISSN: 1502-7708</identifier><identifier>DOI: 10.3109/00365528509088864</identifier><identifier>PMID: 4081626</identifier><identifier>CODEN: SJGRA4</identifier><language>eng</language><publisher>Copenhagen: Informa UK Ltd</publisher><subject>Amyloidosis ; Amyloidosis - complications ; Biological and medical sciences ; cancer ; clinical study ; Crohn Disease - complications ; Crohn Disease - mortality ; Crohn Disease - surgery ; Crohn's disease ; Female ; Follow-Up Studies ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Intestinal Neoplasms - complications ; intestinal resection ; Male ; Medical sciences ; Other diseases. Semiology ; Prognosis ; Quality of Life ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><ispartof>Scandinavian journal of gastroenterology, 1985-01, Vol.20 (8), p.1014-1018</ispartof><rights>1985 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1985</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-9efde026d6803956119a20f6386fbc18a6bf07f97cbc80c4f08a4565498438123</citedby><cites>FETCH-LOGICAL-c459t-9efde026d6803956119a20f6386fbc18a6bf07f97cbc80c4f08a4565498438123</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/00365528509088864$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/00365528509088864$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,59626,59732,60415,60521,61200,61235,61381,61416</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8585167$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4081626$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lind, E.</creatorcontrib><creatorcontrib>Fausa, O.</creatorcontrib><creatorcontrib>Gjone, E.</creatorcontrib><creatorcontrib>Mogensen, S. B.</creatorcontrib><title>Crohn's Disease: Treatment and Outcome</title><title>Scandinavian journal of gastroenterology</title><addtitle>Scand J Gastroenterol</addtitle><description>Two hundred and fourteen patients with Crohn's disease (CD) were observed for a mean of 9 years. Colonic CD was diagnosed in 25%, small-bowel CD in 17.5%, and ileocolic CD in 57% of the patients. The cumulative operation rates at 10 years were 47%, 58%, and 71%, respectively. Patients with isolated colonic CD were operated on later in the course of their illness than others (p < 0.05 at 10 years). More than 50% of the patients remained in the 'well being' group regardless of the duration and localization of the disease. The quality of life was better in the non-operated than in the operated group of patients (p < 0.02). Large-bowel carcinomas occurred in three patients. Of six deaths related to CD, two were caused by cancer and three by renal failure due to amyloidosis. The total number of deaths was 3.6 times that expected.</description><subject>Amyloidosis</subject><subject>Amyloidosis - complications</subject><subject>Biological and medical sciences</subject><subject>cancer</subject><subject>clinical study</subject><subject>Crohn Disease - complications</subject><subject>Crohn Disease - mortality</subject><subject>Crohn Disease - surgery</subject><subject>Crohn's disease</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Intestinal Neoplasms - complications</subject><subject>intestinal resection</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Other diseases. Semiology</subject><subject>Prognosis</subject><subject>Quality of Life</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><issn>0036-5521</issn><issn>1502-7708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM9LwzAcxYMoc07_AA_CDjJP1W_aJE3Ui8yfMNhlnkOaJqyjbWbSIvvv7VgdiLDT9_A-7_F9D6FLDLcJBnEHkDBKY05BAOeckSM0xBTiKE2BH6PhVo86AJ-isxBWAEBTIgZoQIBjFrMhmky9W9Y3YfxcBKOCuR8vvFFNZepmrOp8PG8b7Spzjk6sKoO56O8Ifb6-LKbv0Wz-9jF9mkWaUNFEwtjcQMxyxiERlGEsVAyWJZzZTGOuWGYhtSLVmeagiQWuCGWUCE4SjuNkhCa73LV3X60JjayKoE1Zqtq4Nsi0q8vTrtYI4R2ovQvBGyvXvqiU30gMcruN_LdN57nqw9usMvne0Y_R6de9roJWpfWq1kXYY5xyilnaYY87rKit85X6dr7MZaM2pfO_nuTQFw9_7EujymaplTdy5Vpfd_Me6PAD7ySNzg</recordid><startdate>19850101</startdate><enddate>19850101</enddate><creator>Lind, E.</creator><creator>Fausa, O.</creator><creator>Gjone, E.</creator><creator>Mogensen, S. B.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Scandinavian University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19850101</creationdate><title>Crohn's Disease: Treatment and Outcome</title><author>Lind, E. ; Fausa, O. ; Gjone, E. ; Mogensen, S. B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-9efde026d6803956119a20f6386fbc18a6bf07f97cbc80c4f08a4565498438123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Amyloidosis</topic><topic>Amyloidosis - complications</topic><topic>Biological and medical sciences</topic><topic>cancer</topic><topic>clinical study</topic><topic>Crohn Disease - complications</topic><topic>Crohn Disease - mortality</topic><topic>Crohn Disease - surgery</topic><topic>Crohn's disease</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Intestinal Neoplasms - complications</topic><topic>intestinal resection</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Other diseases. Semiology</topic><topic>Prognosis</topic><topic>Quality of Life</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lind, E.</creatorcontrib><creatorcontrib>Fausa, O.</creatorcontrib><creatorcontrib>Gjone, E.</creatorcontrib><creatorcontrib>Mogensen, S. B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lind, E.</au><au>Fausa, O.</au><au>Gjone, E.</au><au>Mogensen, S. B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Crohn's Disease: Treatment and Outcome</atitle><jtitle>Scandinavian journal of gastroenterology</jtitle><addtitle>Scand J Gastroenterol</addtitle><date>1985-01-01</date><risdate>1985</risdate><volume>20</volume><issue>8</issue><spage>1014</spage><epage>1018</epage><pages>1014-1018</pages><issn>0036-5521</issn><eissn>1502-7708</eissn><coden>SJGRA4</coden><abstract>Two hundred and fourteen patients with Crohn's disease (CD) were observed for a mean of 9 years. Colonic CD was diagnosed in 25%, small-bowel CD in 17.5%, and ileocolic CD in 57% of the patients. The cumulative operation rates at 10 years were 47%, 58%, and 71%, respectively. Patients with isolated colonic CD were operated on later in the course of their illness than others (p < 0.05 at 10 years). More than 50% of the patients remained in the 'well being' group regardless of the duration and localization of the disease. The quality of life was better in the non-operated than in the operated group of patients (p < 0.02). Large-bowel carcinomas occurred in three patients. Of six deaths related to CD, two were caused by cancer and three by renal failure due to amyloidosis. The total number of deaths was 3.6 times that expected.</abstract><cop>Copenhagen</cop><cop>Oslo</cop><cop>Stockholm</cop><pub>Informa UK Ltd</pub><pmid>4081626</pmid><doi>10.3109/00365528509088864</doi><tpages>5</tpages></addata></record> |
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source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
subjects | Amyloidosis Amyloidosis - complications Biological and medical sciences cancer clinical study Crohn Disease - complications Crohn Disease - mortality Crohn Disease - surgery Crohn's disease Female Follow-Up Studies Gastroenterology. Liver. Pancreas. Abdomen Humans Intestinal Neoplasms - complications intestinal resection Male Medical sciences Other diseases. Semiology Prognosis Quality of Life Stomach. Duodenum. Small intestine. Colon. Rectum. Anus |
title | Crohn's Disease: Treatment and Outcome |
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