Heme in the treatment of heme deficiency states
The mechanism of regulation of heme biosynthesis is of great interest for both biological and medical reasons. The hepatic and erythropoietic porphyrias are shown to be hereditary or acquired disorders characterized by defects in specific enzymes of the heme biosynthetic pathway. In addition, severa...
Gespeichert in:
| Veröffentlicht in: | Scandinavian journal of clinical & laboratory investigation. Supplement 1990, Vol.201, p.63-75 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 75 |
|---|---|
| container_issue | |
| container_start_page | 63 |
| container_title | Scandinavian journal of clinical & laboratory investigation. Supplement |
| container_volume | 201 |
| creator | Tenhunen, R |
| description | The mechanism of regulation of heme biosynthesis is of great interest for both biological and medical reasons. The hepatic and erythropoietic porphyrias are shown to be hereditary or acquired disorders characterized by defects in specific enzymes of the heme biosynthetic pathway. In addition, several other diseases can be associated with a defect of heme biosynthesis. Heme has become well established in the treatment of acute porphyrias. In recent years, heme has been used increasingly for the treatment of other heme deficiency states as well. |
| doi_str_mv | 10.3109/00365519009085802 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_crossref_primary_10_3109_00365519009085802</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>80130973</sourcerecordid><originalsourceid>FETCH-LOGICAL-c228t-db98b3851533c6d09037306cbca85c35ac2319590f44f51f7eebbb323f3b41513</originalsourceid><addsrcrecordid>eNplkD1PwzAQhj2ASin8AAakTGyhd744tUdUAUWqxAISW2Q7ZzWoSUrsDv33pGrFwvSe9H7o9Ahxh_BICGYOQKVSaAAMaKVBXogpjFeuDH5diesYvwFkiaAmYiJlUaBWUzFfcctZ02Vpw1ka2KaWu5T1IdscjZpD4xvu_CGLySaON-Iy2G3k27POxOfL88dyla_fX9-WT-vcS6lTXjujHWmFisiX9fgSLQhK77zVypOyXhIaZSAURVAYFszOOZIUyBWokGbi4bS7G_qfPcdUtU30vN3ajvt9rDQggVnQGMRT0A99jAOHajc0rR0OFUJ1BFP9AzN27s_je9dy_dc4U6FfXM5dmA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>80130973</pqid></control><display><type>article</type><title>Heme in the treatment of heme deficiency states</title><source>MEDLINE</source><source>Taylor & Francis:Master (3349 titles)</source><source>Taylor & Francis Medical Library - CRKN</source><creator>Tenhunen, R</creator><creatorcontrib>Tenhunen, R</creatorcontrib><description>The mechanism of regulation of heme biosynthesis is of great interest for both biological and medical reasons. The hepatic and erythropoietic porphyrias are shown to be hereditary or acquired disorders characterized by defects in specific enzymes of the heme biosynthetic pathway. In addition, several other diseases can be associated with a defect of heme biosynthesis. Heme has become well established in the treatment of acute porphyrias. In recent years, heme has been used increasingly for the treatment of other heme deficiency states as well.</description><identifier>ISSN: 0085-591X</identifier><identifier>ISSN: 0036-5513</identifier><identifier>DOI: 10.3109/00365519009085802</identifier><identifier>PMID: 2244185</identifier><language>eng</language><publisher>Norway</publisher><subject>Anemia, Sideroblastic - drug therapy ; Heme - deficiency ; Heme - pharmacokinetics ; Heme - therapeutic use ; Humans ; Myelodysplastic Syndromes - drug therapy ; Porphyrias - drug therapy</subject><ispartof>Scandinavian journal of clinical & laboratory investigation. Supplement, 1990, Vol.201, p.63-75</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c228t-db98b3851533c6d09037306cbca85c35ac2319590f44f51f7eebbb323f3b41513</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2244185$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tenhunen, R</creatorcontrib><title>Heme in the treatment of heme deficiency states</title><title>Scandinavian journal of clinical & laboratory investigation. Supplement</title><addtitle>Scand J Clin Lab Invest Suppl</addtitle><description>The mechanism of regulation of heme biosynthesis is of great interest for both biological and medical reasons. The hepatic and erythropoietic porphyrias are shown to be hereditary or acquired disorders characterized by defects in specific enzymes of the heme biosynthetic pathway. In addition, several other diseases can be associated with a defect of heme biosynthesis. Heme has become well established in the treatment of acute porphyrias. In recent years, heme has been used increasingly for the treatment of other heme deficiency states as well.</description><subject>Anemia, Sideroblastic - drug therapy</subject><subject>Heme - deficiency</subject><subject>Heme - pharmacokinetics</subject><subject>Heme - therapeutic use</subject><subject>Humans</subject><subject>Myelodysplastic Syndromes - drug therapy</subject><subject>Porphyrias - drug therapy</subject><issn>0085-591X</issn><issn>0036-5513</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkD1PwzAQhj2ASin8AAakTGyhd744tUdUAUWqxAISW2Q7ZzWoSUrsDv33pGrFwvSe9H7o9Ahxh_BICGYOQKVSaAAMaKVBXogpjFeuDH5diesYvwFkiaAmYiJlUaBWUzFfcctZ02Vpw1ka2KaWu5T1IdscjZpD4xvu_CGLySaON-Iy2G3k27POxOfL88dyla_fX9-WT-vcS6lTXjujHWmFisiX9fgSLQhK77zVypOyXhIaZSAURVAYFszOOZIUyBWokGbi4bS7G_qfPcdUtU30vN3ajvt9rDQggVnQGMRT0A99jAOHajc0rR0OFUJ1BFP9AzN27s_je9dy_dc4U6FfXM5dmA</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>Tenhunen, R</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1990</creationdate><title>Heme in the treatment of heme deficiency states</title><author>Tenhunen, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c228t-db98b3851533c6d09037306cbca85c35ac2319590f44f51f7eebbb323f3b41513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Anemia, Sideroblastic - drug therapy</topic><topic>Heme - deficiency</topic><topic>Heme - pharmacokinetics</topic><topic>Heme - therapeutic use</topic><topic>Humans</topic><topic>Myelodysplastic Syndromes - drug therapy</topic><topic>Porphyrias - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tenhunen, R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of clinical & laboratory investigation. Supplement</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tenhunen, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Heme in the treatment of heme deficiency states</atitle><jtitle>Scandinavian journal of clinical & laboratory investigation. Supplement</jtitle><addtitle>Scand J Clin Lab Invest Suppl</addtitle><date>1990</date><risdate>1990</risdate><volume>201</volume><spage>63</spage><epage>75</epage><pages>63-75</pages><issn>0085-591X</issn><issn>0036-5513</issn><abstract>The mechanism of regulation of heme biosynthesis is of great interest for both biological and medical reasons. The hepatic and erythropoietic porphyrias are shown to be hereditary or acquired disorders characterized by defects in specific enzymes of the heme biosynthetic pathway. In addition, several other diseases can be associated with a defect of heme biosynthesis. Heme has become well established in the treatment of acute porphyrias. In recent years, heme has been used increasingly for the treatment of other heme deficiency states as well.</abstract><cop>Norway</cop><pmid>2244185</pmid><doi>10.3109/00365519009085802</doi><tpages>13</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0085-591X |
| ispartof | Scandinavian journal of clinical & laboratory investigation. Supplement, 1990, Vol.201, p.63-75 |
| issn | 0085-591X 0036-5513 |
| language | eng |
| recordid | cdi_crossref_primary_10_3109_00365519009085802 |
| source | MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN |
| subjects | Anemia, Sideroblastic - drug therapy Heme - deficiency Heme - pharmacokinetics Heme - therapeutic use Humans Myelodysplastic Syndromes - drug therapy Porphyrias - drug therapy |
| title | Heme in the treatment of heme deficiency states |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-22T12%3A31%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Heme%20in%20the%20treatment%20of%20heme%20deficiency%20states&rft.jtitle=Scandinavian%20journal%20of%20clinical%20&%20laboratory%20investigation.%20Supplement&rft.au=Tenhunen,%20R&rft.date=1990&rft.volume=201&rft.spage=63&rft.epage=75&rft.pages=63-75&rft.issn=0085-591X&rft_id=info:doi/10.3109/00365519009085802&rft_dat=%3Cproquest_cross%3E80130973%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=80130973&rft_id=info:pmid/2244185&rfr_iscdi=true |