Is an Imbalanced Calcium-Homeostasis Responsible for the Experimentally Induced Endolymphatic Hydrops?
The target of the investigations were the presumably ion-transporting cells of the vestibular organ, i.e. the area of 'dark cells' of the semicircular canal and utriculus. Those cells have been assayed for structural changes by LM and EM and for alterations of the ionic content (LAMMA) in...
Gespeichert in:
| Veröffentlicht in: | Acta oto-laryngologica 1986, Vol.102 (1-2), p.93-98 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 98 |
|---|---|
| container_issue | 1-2 |
| container_start_page | 93 |
| container_title | Acta oto-laryngologica |
| container_volume | 102 |
| creator | zum Gottesberge-Orsulakova, A.-M. Meyer Kaufmann, R. |
| description | The target of the investigations were the presumably ion-transporting cells of the vestibular organ, i.e. the area of 'dark cells' of the semicircular canal and utriculus. Those cells have been assayed for structural changes by LM and EM and for alterations of the ionic content (LAMMA) in coloured guinea pigs with unilaterally induced endolymphatic hydrops. Characteristically changed structures of the secretory epithelium and disordered pigmentation in the vestibular organ were noted. Those cellular alterations were accompanied by intracellular ionic changes, especially an increased level of Ca2+ in the light cells and melanocytes. Our investigations show that, at least for experimental hydrops, an imbalanced homeostasis of Ca exists that may be responsible for the enlargement of the endolymphatic space. |
| doi_str_mv | 10.3109/00016488609108651 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_crossref_primary_10_3109_00016488609108651</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>76981564</sourcerecordid><originalsourceid>FETCH-LOGICAL-c430t-6def4961d0c70051fac033b59dc473ced69229505f76f41544e9746404ed09093</originalsourceid><addsrcrecordid>eNp9kF2L1DAUhoMo6-zqD_BC6IV4V_dk8tEGBVmGWWdgQRC9LpnkhOmSNjVpcfvvTZlxQRb26hDeD_I-hLyj8IlRUNcAQCWvawmKQi0FfUFWNJ9yvRb0JVktepkN6jW5TOl-eapaXJALVjEllVgRt0-F7ot9d9Be9wZtsdHetFNX7kKHIY06tan4gWkIfWoPHgsXYjEesdg-DBjbDvtRez8X-95OS3zb2-DnbjjqsTXFbrYxDOnrG_LKaZ_w7flekV-325-bXXn3_dt-c3NXGs5gLKVFx5WkFkwFIKjTBhg7CGUNr1iul2q9VgKEq6TjVHCOquKSA0cLChS7Ih9PvUMMvydMY9O1yaDP2zBMqamkqqmQPBvpyWhiSCmia4Y8Rse5odAsbJsnbHPm_bl8OnRoHxNnmFn_cNZ1Mtq7mIG26dFW1yAqvtR8OdnaPrPs9J8QvW1GPfsQ_2XYc7_4_F_8iNqPR6MjNvdhin3G-8yGv2hPpho</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>76981564</pqid></control><display><type>article</type><title>Is an Imbalanced Calcium-Homeostasis Responsible for the Experimentally Induced Endolymphatic Hydrops?</title><source>Taylor & Francis Online</source><source>MEDLINE</source><source>Taylor & Francis Medical Library - CRKN</source><creator>zum Gottesberge-Orsulakova, A.-M. Meyer ; Kaufmann, R.</creator><creatorcontrib>zum Gottesberge-Orsulakova, A.-M. Meyer ; Kaufmann, R.</creatorcontrib><description>The target of the investigations were the presumably ion-transporting cells of the vestibular organ, i.e. the area of 'dark cells' of the semicircular canal and utriculus. Those cells have been assayed for structural changes by LM and EM and for alterations of the ionic content (LAMMA) in coloured guinea pigs with unilaterally induced endolymphatic hydrops. Characteristically changed structures of the secretory epithelium and disordered pigmentation in the vestibular organ were noted. Those cellular alterations were accompanied by intracellular ionic changes, especially an increased level of Ca2+ in the light cells and melanocytes. Our investigations show that, at least for experimental hydrops, an imbalanced homeostasis of Ca exists that may be responsible for the enlargement of the endolymphatic space.</description><identifier>ISSN: 0001-6489</identifier><identifier>EISSN: 1651-2251</identifier><identifier>DOI: 10.3109/00016488609108651</identifier><identifier>PMID: 3739695</identifier><identifier>CODEN: AOLAAJ</identifier><language>eng</language><publisher>Stockholm: Informa UK Ltd</publisher><subject>Animals ; Biological and medical sciences ; Biological Transport, Active ; Calcium - physiology ; Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology ; Edema - etiology ; Edema - metabolism ; Endolymphatic Duct ; Guinea Pigs ; Homeostasis ; Labyrinth Diseases - etiology ; Labyrinth Diseases - metabolism ; Lasers ; Medical sciences ; melanin ; Melanocytes - metabolism ; Melanocytes - ultrastructure ; microprobe analysis ; Microscopy, Electron ; Otorhinolaryngology. Stomatology ; Saccule and Utricle - metabolism ; Saccule and Utricle - ultrastructure ; Semicircular Canals - metabolism ; Semicircular Canals - ultrastructure ; Space life sciences ; Time Factors ; vestibular organ</subject><ispartof>Acta oto-laryngologica, 1986, Vol.102 (1-2), p.93-98</ispartof><rights>1986 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1986</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-6def4961d0c70051fac033b59dc473ced69229505f76f41544e9746404ed09093</citedby><cites>FETCH-LOGICAL-c430t-6def4961d0c70051fac033b59dc473ced69229505f76f41544e9746404ed09093</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/00016488609108651$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/00016488609108651$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,780,784,4024,27923,27924,27925,59647,59753,60436,60542,61221,61256,61402,61437</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8805741$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3739695$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>zum Gottesberge-Orsulakova, A.-M. Meyer</creatorcontrib><creatorcontrib>Kaufmann, R.</creatorcontrib><title>Is an Imbalanced Calcium-Homeostasis Responsible for the Experimentally Induced Endolymphatic Hydrops?</title><title>Acta oto-laryngologica</title><addtitle>Acta Otolaryngol</addtitle><description>The target of the investigations were the presumably ion-transporting cells of the vestibular organ, i.e. the area of 'dark cells' of the semicircular canal and utriculus. Those cells have been assayed for structural changes by LM and EM and for alterations of the ionic content (LAMMA) in coloured guinea pigs with unilaterally induced endolymphatic hydrops. Characteristically changed structures of the secretory epithelium and disordered pigmentation in the vestibular organ were noted. Those cellular alterations were accompanied by intracellular ionic changes, especially an increased level of Ca2+ in the light cells and melanocytes. Our investigations show that, at least for experimental hydrops, an imbalanced homeostasis of Ca exists that may be responsible for the enlargement of the endolymphatic space.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Biological Transport, Active</subject><subject>Calcium - physiology</subject><subject>Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology</subject><subject>Edema - etiology</subject><subject>Edema - metabolism</subject><subject>Endolymphatic Duct</subject><subject>Guinea Pigs</subject><subject>Homeostasis</subject><subject>Labyrinth Diseases - etiology</subject><subject>Labyrinth Diseases - metabolism</subject><subject>Lasers</subject><subject>Medical sciences</subject><subject>melanin</subject><subject>Melanocytes - metabolism</subject><subject>Melanocytes - ultrastructure</subject><subject>microprobe analysis</subject><subject>Microscopy, Electron</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Saccule and Utricle - metabolism</subject><subject>Saccule and Utricle - ultrastructure</subject><subject>Semicircular Canals - metabolism</subject><subject>Semicircular Canals - ultrastructure</subject><subject>Space life sciences</subject><subject>Time Factors</subject><subject>vestibular organ</subject><issn>0001-6489</issn><issn>1651-2251</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF2L1DAUhoMo6-zqD_BC6IV4V_dk8tEGBVmGWWdgQRC9LpnkhOmSNjVpcfvvTZlxQRb26hDeD_I-hLyj8IlRUNcAQCWvawmKQi0FfUFWNJ9yvRb0JVktepkN6jW5TOl-eapaXJALVjEllVgRt0-F7ot9d9Be9wZtsdHetFNX7kKHIY06tan4gWkIfWoPHgsXYjEesdg-DBjbDvtRez8X-95OS3zb2-DnbjjqsTXFbrYxDOnrG_LKaZ_w7flekV-325-bXXn3_dt-c3NXGs5gLKVFx5WkFkwFIKjTBhg7CGUNr1iul2q9VgKEq6TjVHCOquKSA0cLChS7Ih9PvUMMvydMY9O1yaDP2zBMqamkqqmQPBvpyWhiSCmia4Y8Rse5odAsbJsnbHPm_bl8OnRoHxNnmFn_cNZ1Mtq7mIG26dFW1yAqvtR8OdnaPrPs9J8QvW1GPfsQ_2XYc7_4_F_8iNqPR6MjNvdhin3G-8yGv2hPpho</recordid><startdate>1986</startdate><enddate>1986</enddate><creator>zum Gottesberge-Orsulakova, A.-M. Meyer</creator><creator>Kaufmann, R.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Taylor and Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>1986</creationdate><title>Is an Imbalanced Calcium-Homeostasis Responsible for the Experimentally Induced Endolymphatic Hydrops?</title><author>zum Gottesberge-Orsulakova, A.-M. Meyer ; Kaufmann, R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-6def4961d0c70051fac033b59dc473ced69229505f76f41544e9746404ed09093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Biological Transport, Active</topic><topic>Calcium - physiology</topic><topic>Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology</topic><topic>Edema - etiology</topic><topic>Edema - metabolism</topic><topic>Endolymphatic Duct</topic><topic>Guinea Pigs</topic><topic>Homeostasis</topic><topic>Labyrinth Diseases - etiology</topic><topic>Labyrinth Diseases - metabolism</topic><topic>Lasers</topic><topic>Medical sciences</topic><topic>melanin</topic><topic>Melanocytes - metabolism</topic><topic>Melanocytes - ultrastructure</topic><topic>microprobe analysis</topic><topic>Microscopy, Electron</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Saccule and Utricle - metabolism</topic><topic>Saccule and Utricle - ultrastructure</topic><topic>Semicircular Canals - metabolism</topic><topic>Semicircular Canals - ultrastructure</topic><topic>Space life sciences</topic><topic>Time Factors</topic><topic>vestibular organ</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>zum Gottesberge-Orsulakova, A.-M. Meyer</creatorcontrib><creatorcontrib>Kaufmann, R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Acta oto-laryngologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>zum Gottesberge-Orsulakova, A.-M. Meyer</au><au>Kaufmann, R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is an Imbalanced Calcium-Homeostasis Responsible for the Experimentally Induced Endolymphatic Hydrops?</atitle><jtitle>Acta oto-laryngologica</jtitle><addtitle>Acta Otolaryngol</addtitle><date>1986</date><risdate>1986</risdate><volume>102</volume><issue>1-2</issue><spage>93</spage><epage>98</epage><pages>93-98</pages><issn>0001-6489</issn><eissn>1651-2251</eissn><coden>AOLAAJ</coden><abstract>The target of the investigations were the presumably ion-transporting cells of the vestibular organ, i.e. the area of 'dark cells' of the semicircular canal and utriculus. Those cells have been assayed for structural changes by LM and EM and for alterations of the ionic content (LAMMA) in coloured guinea pigs with unilaterally induced endolymphatic hydrops. Characteristically changed structures of the secretory epithelium and disordered pigmentation in the vestibular organ were noted. Those cellular alterations were accompanied by intracellular ionic changes, especially an increased level of Ca2+ in the light cells and melanocytes. Our investigations show that, at least for experimental hydrops, an imbalanced homeostasis of Ca exists that may be responsible for the enlargement of the endolymphatic space.</abstract><cop>Stockholm</cop><pub>Informa UK Ltd</pub><pmid>3739695</pmid><doi>10.3109/00016488609108651</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-6489 |
| ispartof | Acta oto-laryngologica, 1986, Vol.102 (1-2), p.93-98 |
| issn | 0001-6489 1651-2251 |
| language | eng |
| recordid | cdi_crossref_primary_10_3109_00016488609108651 |
| source | Taylor & Francis Online; MEDLINE; Taylor & Francis Medical Library - CRKN |
| subjects | Animals Biological and medical sciences Biological Transport, Active Calcium - physiology Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology Edema - etiology Edema - metabolism Endolymphatic Duct Guinea Pigs Homeostasis Labyrinth Diseases - etiology Labyrinth Diseases - metabolism Lasers Medical sciences melanin Melanocytes - metabolism Melanocytes - ultrastructure microprobe analysis Microscopy, Electron Otorhinolaryngology. Stomatology Saccule and Utricle - metabolism Saccule and Utricle - ultrastructure Semicircular Canals - metabolism Semicircular Canals - ultrastructure Space life sciences Time Factors vestibular organ |
| title | Is an Imbalanced Calcium-Homeostasis Responsible for the Experimentally Induced Endolymphatic Hydrops? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T21%3A19%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Is%20an%20Imbalanced%20Calcium-Homeostasis%20Responsible%20for%20the%20Experimentally%20Induced%20Endolymphatic%20Hydrops?&rft.jtitle=Acta%20oto-laryngologica&rft.au=zum%20Gottesberge-Orsulakova,%20A.-M.%20Meyer&rft.date=1986&rft.volume=102&rft.issue=1-2&rft.spage=93&rft.epage=98&rft.pages=93-98&rft.issn=0001-6489&rft.eissn=1651-2251&rft.coden=AOLAAJ&rft_id=info:doi/10.3109/00016488609108651&rft_dat=%3Cproquest_cross%3E76981564%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=76981564&rft_id=info:pmid/3739695&rfr_iscdi=true |