Laparoscopic instillation of hyperosmolar glucose vs. expectant management of tubal pregnancies with serum hCG≤2500 mlU/mL
Objective. To compare expectant management with local instillation of 50% glucose solution for tubal pregnancies with a serum hCG level ≤2500 mlU/mL. Design. Prospective, non-randomized, comparative clinical study. Setting. Two university departments. Patients. One hundred and twenty-eight patients...
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| Veröffentlicht in: | Acta obstetricia et gynecologica Scandinavica 1997-08, Vol.76 (8), p.797-800 |
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| container_title | Acta obstetricia et gynecologica Scandinavica |
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| creator | Lang, Peter F. J. Mäkinen, Juha I. Irjala, Kerttu M. A. Rantala, Mika Hönigl, Werner Tamussino, Karl Haas, Josef |
| description | Objective. To compare expectant management with local instillation of 50% glucose solution for tubal pregnancies with a serum hCG level ≤2500 mlU/mL. Design. Prospective, non-randomized, comparative clinical study.
Setting. Two university departments.
Patients. One hundred and twenty-eight patients with laparoscopically-confirmed tubal pregnancy and serum hCG ≤2500 mlU/mL.
Interventions. Eighty patients in Graz were treated with laparoscopic instillation of 50% glucose solution and 48 patients in Turku were followed expectantly.
Main outcome measures. Resolution of hCG excretion, need for further interventions.
Results. Seventy-four of the 80 patients (92%) in the glucose group (32 of 33 with an initial hCG ≤250 mlU/mL and 42 of 47 with hCG 251-2500 mlU/mL) and 36 of 48 (75%) patients in the expectant group (19 of 23 with an initial hCG ≤250 mlU/mL and 17 of 25 with hCG 251-2500 mlU/mL) had resolution of the pregnancy with no further intervention (p=0.008, chi-square test, odds ratio 0.24).
Conclusions. Glucose instillation is superior to expectant management for patients with early tubal pregnancy. |
| doi_str_mv | 10.3109/00016349709024350 |
| format | Article |
| fullrecord | <record><control><sourceid>istex_cross</sourceid><recordid>TN_cdi_crossref_primary_10_3109_00016349709024350</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ark_67375_WNG_QKGX3V4T_W</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2707-7ce9b7a8d209813e7d138ea6ff7bc8fbe21c19d9c19ae6d9cee6c7ae2371591b3</originalsourceid><addsrcrecordid>eNqFkEtO3EAQhltRImVCcoDs-gKGfthuW1mhEThRRiAkHtm1yj3lcUP7oW4PMFIuwD04GSehR4PYIMGmHqr_K1X9hPzkbF9yVh4wxngu01KxkolUZuwTmfGcsYSlXHwms-082Qq-km8hXMdOqLSYkf8LGMEPwQyjNdT2YbLOwWSHng4NbTcjxmE3OPB05dZmCEhvwz7F-xHNBP1EO-hhhR3GMgLTugZHR4-rHnpjMdA7O7U0oF93tJ1XTw-PImOMdu7ioFt8J18acAF_vOQ9cnF8dD7_nSxOqz_zw0VihGIqUQbLWkGxFKwsuES15LJAyJtG1aZoahTc8HJZxgCYx4yYGwUopOJZyWu5R_hur4nPBI-NHr3twG80Z3prn35jX2TyHXNnHW4-BvThaSVYpiKY7EAbJrx_BcHf6FxJlemrk0qf_a3-ycv0XF9F_a8Xfd8MvoMWwU2tAY_6elj7PhrzzpnPYI2W6w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Laparoscopic instillation of hyperosmolar glucose vs. expectant management of tubal pregnancies with serum hCG≤2500 mlU/mL</title><source>Wiley-Blackwell Journals</source><creator>Lang, Peter F. J. ; Mäkinen, Juha I. ; Irjala, Kerttu M. A. ; Rantala, Mika ; Hönigl, Werner ; Tamussino, Karl ; Haas, Josef</creator><creatorcontrib>Lang, Peter F. J. ; Mäkinen, Juha I. ; Irjala, Kerttu M. A. ; Rantala, Mika ; Hönigl, Werner ; Tamussino, Karl ; Haas, Josef</creatorcontrib><description>Objective. To compare expectant management with local instillation of 50% glucose solution for tubal pregnancies with a serum hCG level ≤2500 mlU/mL. Design. Prospective, non-randomized, comparative clinical study.
Setting. Two university departments.
Patients. One hundred and twenty-eight patients with laparoscopically-confirmed tubal pregnancy and serum hCG ≤2500 mlU/mL.
Interventions. Eighty patients in Graz were treated with laparoscopic instillation of 50% glucose solution and 48 patients in Turku were followed expectantly.
Main outcome measures. Resolution of hCG excretion, need for further interventions.
Results. Seventy-four of the 80 patients (92%) in the glucose group (32 of 33 with an initial hCG ≤250 mlU/mL and 42 of 47 with hCG 251-2500 mlU/mL) and 36 of 48 (75%) patients in the expectant group (19 of 23 with an initial hCG ≤250 mlU/mL and 17 of 25 with hCG 251-2500 mlU/mL) had resolution of the pregnancy with no further intervention (p=0.008, chi-square test, odds ratio 0.24).
Conclusions. Glucose instillation is superior to expectant management for patients with early tubal pregnancy.</description><identifier>ISSN: 0001-6349</identifier><identifier>EISSN: 1600-0412</identifier><identifier>DOI: 10.3109/00016349709024350</identifier><language>eng</language><publisher>Oxford, UK: Informa UK Ltd</publisher><subject>ectopic pregnancy ; expectant management ; glucose installation ; hCG levels ; spontaneous reaction ; tubal pregnancy</subject><ispartof>Acta obstetricia et gynecologica Scandinavica, 1997-08, Vol.76 (8), p.797-800</ispartof><rights>1997 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1997</rights><rights>1997 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2707-7ce9b7a8d209813e7d138ea6ff7bc8fbe21c19d9c19ae6d9cee6c7ae2371591b3</citedby><cites>FETCH-LOGICAL-c2707-7ce9b7a8d209813e7d138ea6ff7bc8fbe21c19d9c19ae6d9cee6c7ae2371591b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.3109%2F00016349709024350$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.3109%2F00016349709024350$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids></links><search><creatorcontrib>Lang, Peter F. J.</creatorcontrib><creatorcontrib>Mäkinen, Juha I.</creatorcontrib><creatorcontrib>Irjala, Kerttu M. A.</creatorcontrib><creatorcontrib>Rantala, Mika</creatorcontrib><creatorcontrib>Hönigl, Werner</creatorcontrib><creatorcontrib>Tamussino, Karl</creatorcontrib><creatorcontrib>Haas, Josef</creatorcontrib><title>Laparoscopic instillation of hyperosmolar glucose vs. expectant management of tubal pregnancies with serum hCG≤2500 mlU/mL</title><title>Acta obstetricia et gynecologica Scandinavica</title><description>Objective. To compare expectant management with local instillation of 50% glucose solution for tubal pregnancies with a serum hCG level ≤2500 mlU/mL. Design. Prospective, non-randomized, comparative clinical study.
Setting. Two university departments.
Patients. One hundred and twenty-eight patients with laparoscopically-confirmed tubal pregnancy and serum hCG ≤2500 mlU/mL.
Interventions. Eighty patients in Graz were treated with laparoscopic instillation of 50% glucose solution and 48 patients in Turku were followed expectantly.
Main outcome measures. Resolution of hCG excretion, need for further interventions.
Results. Seventy-four of the 80 patients (92%) in the glucose group (32 of 33 with an initial hCG ≤250 mlU/mL and 42 of 47 with hCG 251-2500 mlU/mL) and 36 of 48 (75%) patients in the expectant group (19 of 23 with an initial hCG ≤250 mlU/mL and 17 of 25 with hCG 251-2500 mlU/mL) had resolution of the pregnancy with no further intervention (p=0.008, chi-square test, odds ratio 0.24).
Conclusions. Glucose instillation is superior to expectant management for patients with early tubal pregnancy.</description><subject>ectopic pregnancy</subject><subject>expectant management</subject><subject>glucose installation</subject><subject>hCG levels</subject><subject>spontaneous reaction</subject><subject>tubal pregnancy</subject><issn>0001-6349</issn><issn>1600-0412</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNqFkEtO3EAQhltRImVCcoDs-gKGfthuW1mhEThRRiAkHtm1yj3lcUP7oW4PMFIuwD04GSehR4PYIMGmHqr_K1X9hPzkbF9yVh4wxngu01KxkolUZuwTmfGcsYSlXHwms-082Qq-km8hXMdOqLSYkf8LGMEPwQyjNdT2YbLOwWSHng4NbTcjxmE3OPB05dZmCEhvwz7F-xHNBP1EO-hhhR3GMgLTugZHR4-rHnpjMdA7O7U0oF93tJ1XTw-PImOMdu7ioFt8J18acAF_vOQ9cnF8dD7_nSxOqz_zw0VihGIqUQbLWkGxFKwsuES15LJAyJtG1aZoahTc8HJZxgCYx4yYGwUopOJZyWu5R_hur4nPBI-NHr3twG80Z3prn35jX2TyHXNnHW4-BvThaSVYpiKY7EAbJrx_BcHf6FxJlemrk0qf_a3-ycv0XF9F_a8Xfd8MvoMWwU2tAY_6elj7PhrzzpnPYI2W6w</recordid><startdate>199708</startdate><enddate>199708</enddate><creator>Lang, Peter F. J.</creator><creator>Mäkinen, Juha I.</creator><creator>Irjala, Kerttu M. A.</creator><creator>Rantala, Mika</creator><creator>Hönigl, Werner</creator><creator>Tamussino, Karl</creator><creator>Haas, Josef</creator><general>Informa UK Ltd</general><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>199708</creationdate><title>Laparoscopic instillation of hyperosmolar glucose vs. expectant management of tubal pregnancies with serum hCG≤2500 mlU/mL</title><author>Lang, Peter F. J. ; Mäkinen, Juha I. ; Irjala, Kerttu M. A. ; Rantala, Mika ; Hönigl, Werner ; Tamussino, Karl ; Haas, Josef</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2707-7ce9b7a8d209813e7d138ea6ff7bc8fbe21c19d9c19ae6d9cee6c7ae2371591b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>ectopic pregnancy</topic><topic>expectant management</topic><topic>glucose installation</topic><topic>hCG levels</topic><topic>spontaneous reaction</topic><topic>tubal pregnancy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lang, Peter F. J.</creatorcontrib><creatorcontrib>Mäkinen, Juha I.</creatorcontrib><creatorcontrib>Irjala, Kerttu M. A.</creatorcontrib><creatorcontrib>Rantala, Mika</creatorcontrib><creatorcontrib>Hönigl, Werner</creatorcontrib><creatorcontrib>Tamussino, Karl</creatorcontrib><creatorcontrib>Haas, Josef</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><jtitle>Acta obstetricia et gynecologica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lang, Peter F. J.</au><au>Mäkinen, Juha I.</au><au>Irjala, Kerttu M. A.</au><au>Rantala, Mika</au><au>Hönigl, Werner</au><au>Tamussino, Karl</au><au>Haas, Josef</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Laparoscopic instillation of hyperosmolar glucose vs. expectant management of tubal pregnancies with serum hCG≤2500 mlU/mL</atitle><jtitle>Acta obstetricia et gynecologica Scandinavica</jtitle><date>1997-08</date><risdate>1997</risdate><volume>76</volume><issue>8</issue><spage>797</spage><epage>800</epage><pages>797-800</pages><issn>0001-6349</issn><eissn>1600-0412</eissn><abstract>Objective. To compare expectant management with local instillation of 50% glucose solution for tubal pregnancies with a serum hCG level ≤2500 mlU/mL. Design. Prospective, non-randomized, comparative clinical study.
Setting. Two university departments.
Patients. One hundred and twenty-eight patients with laparoscopically-confirmed tubal pregnancy and serum hCG ≤2500 mlU/mL.
Interventions. Eighty patients in Graz were treated with laparoscopic instillation of 50% glucose solution and 48 patients in Turku were followed expectantly.
Main outcome measures. Resolution of hCG excretion, need for further interventions.
Results. Seventy-four of the 80 patients (92%) in the glucose group (32 of 33 with an initial hCG ≤250 mlU/mL and 42 of 47 with hCG 251-2500 mlU/mL) and 36 of 48 (75%) patients in the expectant group (19 of 23 with an initial hCG ≤250 mlU/mL and 17 of 25 with hCG 251-2500 mlU/mL) had resolution of the pregnancy with no further intervention (p=0.008, chi-square test, odds ratio 0.24).
Conclusions. Glucose instillation is superior to expectant management for patients with early tubal pregnancy.</abstract><cop>Oxford, UK</cop><pub>Informa UK Ltd</pub><doi>10.3109/00016349709024350</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Acta obstetricia et gynecologica Scandinavica, 1997-08, Vol.76 (8), p.797-800 |
| issn | 0001-6349 1600-0412 |
| language | eng |
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| source | Wiley-Blackwell Journals |
| subjects | ectopic pregnancy expectant management glucose installation hCG levels spontaneous reaction tubal pregnancy |
| title | Laparoscopic instillation of hyperosmolar glucose vs. expectant management of tubal pregnancies with serum hCG≤2500 mlU/mL |
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