The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses

The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses

Aim: The present study aims to examine the effectiveness of the neutrophil-to-lymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Method: In this retrospective study, radiological, neurological, and surgical data obtained from the medical records of healthy volunteers (...

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Veröffentlicht in:Acta medica Alanya 2021-12, Vol.5 (3), p.308-316
Hauptverfasser: ÇALIŞKAN, Tezcan, YİLMAZ, Ibrahim, HACIOGLU, Fatma, ERSOZ, Emel, DOĞAN, Mustafa, KARAARSLAN, Numan
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container_title Acta medica Alanya
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creator ÇALIŞKAN, Tezcan
YİLMAZ, Ibrahim
HACIOGLU, Fatma
ERSOZ, Emel
DOĞAN, Mustafa
KARAARSLAN, Numan
description Aim: The present study aims to examine the effectiveness of the neutrophil-to-lymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Method: In this retrospective study, radiological, neurological, and surgical data obtained from the medical records of healthy volunteers (n = 10) who presented to the hospital for check-ups and patients with brain abscesses who were treated (n = 10) were evaluated statistically. Alpha significance value was accepted as
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Method: In this retrospective study, radiological, neurological, and surgical data obtained from the medical records of healthy volunteers (n = 10) who presented to the hospital for check-ups and patients with brain abscesses who were treated (n = 10) were evaluated statistically. Alpha significance value was accepted as <0.05. Results: Comparisons between groups revealed that the erythrocyte sedimentation rate, C-reactive protein, leukocyte, and neutrophil values were statistically significant (P <0.05) while lymphocyte value was not statistically significant (P >0.05). The preoperative neutrophil-to-lymphocyte ratio in cases diagnosed with brain abscesses showed statistical significance compared to that in the healthy volunteers (P <0.05) and the neutrophil-to-lymphocyte ratio increased 3.31-fold in the study group compared to the healthy volunteers. Conclusion: A strong positive strong relationship between the neutrophil-to-lymphocyte ratio and abscess size (r = 0.662; P = 0.037) was observed. An increased neutrophil-to-lymphocyte ratio may serve as an early warning signal of brain abscesses. Keywords: Antibiotic treatment; brain abscess; low-cost diagnosis method; magnetic resonance image; neutrophil-to-lymphocyte ratio. Amaç: Bu makalede; beyin apsesi tanısı alan olgularda, nötrofil-lenfosit oranı (NLO)’nın, tanı ve tedavide önemli olup olmadığının incelenmesi amaçlandı. Metod: Retrospektif dizayna sahip araştırmada, hastaneye kontrol için gelen sağlıklı bireyler (n=10) ile beyin apsesi olan ve tedavi edilen olgular (n=10)’dan elde edilen radyolojik, nörolojik ve cerrahi veriler istatistiksel olarak değerlendirmeye alındı. Alfa anlamlılık değeri <0,05 olarak kabul edildi. Bulgular: Gruplar arası karşılaştırmalar sonucunda; eritrosit çökelme oranı (ESR), C-reaktif protein (CRP), lökosit (WBC) ve nötrofil (NEU) değerleri istatistiksel olarak anlamlı iken (P<0,05), lenfosit (LYMPH) değerinde istatistiksel olarak anlamlılık görülmedi (P>0,05). Sağlıklı bireylere oranla beyin apsesi tanısı alan olgulara ait preoperatif NLO değerlerinin istatistiksel olarak anlamlılık (P<0,05) gösterdiği ve NLO değerinin sağlıklı bireylere oranla yaklaşık 3,31 kat artış gösterdiği kaydedildi. Sonuç: NLO oranı ile abse boyutu arasında (r=0,662; P=0,037) pozitif yönde kuvvetli ilişki bulunmaktadır. Artış gösteren NLO, beyin apsesinin tanısında erken uyarı sinyali olarak hizmet edebilir.]]></description><identifier>ISSN: 2587-0319</identifier><identifier>EISSN: 2587-0319</identifier><identifier>DOI: 10.30565/medalanya.946066</identifier><language>eng</language><ispartof>Acta medica Alanya, 2021-12, Vol.5 (3), p.308-316</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c856-db0d9d0d7fdfd10ef3ad24ff2a78ade731e750981bdeec1b9f2aefc33c6154203</cites><orcidid>0000-0002-5906-5859 ; 0000-0003-2003-6337 ; 0000-0001-7735-0584 ; 0000-0002-3341-925X ; 0000-0002-3605-2350 ; 0000-0001-5590-0637</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>ÇALIŞKAN, Tezcan</creatorcontrib><creatorcontrib>YİLMAZ, Ibrahim</creatorcontrib><creatorcontrib>HACIOGLU, Fatma</creatorcontrib><creatorcontrib>ERSOZ, Emel</creatorcontrib><creatorcontrib>DOĞAN, Mustafa</creatorcontrib><creatorcontrib>KARAARSLAN, Numan</creatorcontrib><title>The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses</title><title>Acta medica Alanya</title><description><![CDATA[Aim: The present study aims to examine the effectiveness of the neutrophil-to-lymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Method: In this retrospective study, radiological, neurological, and surgical data obtained from the medical records of healthy volunteers (n = 10) who presented to the hospital for check-ups and patients with brain abscesses who were treated (n = 10) were evaluated statistically. Alpha significance value was accepted as <0.05. Results: Comparisons between groups revealed that the erythrocyte sedimentation rate, C-reactive protein, leukocyte, and neutrophil values were statistically significant (P <0.05) while lymphocyte value was not statistically significant (P >0.05). The preoperative neutrophil-to-lymphocyte ratio in cases diagnosed with brain abscesses showed statistical significance compared to that in the healthy volunteers (P <0.05) and the neutrophil-to-lymphocyte ratio increased 3.31-fold in the study group compared to the healthy volunteers. Conclusion: A strong positive strong relationship between the neutrophil-to-lymphocyte ratio and abscess size (r = 0.662; P = 0.037) was observed. An increased neutrophil-to-lymphocyte ratio may serve as an early warning signal of brain abscesses. Keywords: Antibiotic treatment; brain abscess; low-cost diagnosis method; magnetic resonance image; neutrophil-to-lymphocyte ratio. Amaç: Bu makalede; beyin apsesi tanısı alan olgularda, nötrofil-lenfosit oranı (NLO)’nın, tanı ve tedavide önemli olup olmadığının incelenmesi amaçlandı. Metod: Retrospektif dizayna sahip araştırmada, hastaneye kontrol için gelen sağlıklı bireyler (n=10) ile beyin apsesi olan ve tedavi edilen olgular (n=10)’dan elde edilen radyolojik, nörolojik ve cerrahi veriler istatistiksel olarak değerlendirmeye alındı. Alfa anlamlılık değeri <0,05 olarak kabul edildi. Bulgular: Gruplar arası karşılaştırmalar sonucunda; eritrosit çökelme oranı (ESR), C-reaktif protein (CRP), lökosit (WBC) ve nötrofil (NEU) değerleri istatistiksel olarak anlamlı iken (P<0,05), lenfosit (LYMPH) değerinde istatistiksel olarak anlamlılık görülmedi (P>0,05). Sağlıklı bireylere oranla beyin apsesi tanısı alan olgulara ait preoperatif NLO değerlerinin istatistiksel olarak anlamlılık (P<0,05) gösterdiği ve NLO değerinin sağlıklı bireylere oranla yaklaşık 3,31 kat artış gösterdiği kaydedildi. Sonuç: NLO oranı ile abse boyutu arasında (r=0,662; P=0,037) pozitif yönde kuvvetli ilişki bulunmaktadır. Artış gösteren NLO, beyin apsesinin tanısında erken uyarı sinyali olarak hizmet edebilir.]]></description><issn>2587-0319</issn><issn>2587-0319</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNpNkM1OwzAQhC0EElXpA3DzC6Ss7dhJjqUUihR-hMI52tjrNihxUJxL355CEeI0oxnNHD7GrgUsFWijb3py2GE44LJIDRhzxmZS51kCShTn__wlW8T4AQAyz1Jt5Iy9V3viG-_JTpEPnj-Xb3wIfDqmdy3uwhDbyDE4_rrHsUc7dMOutdjxJwy4o57C9D27HbENfNVESzFSvGIXHrtIi1-ds-p-U623Sfny8LhelYnNtUlcA65w4DLvvBNAXqGTqfcSsxwdZUpQpqHIReOIrGiKY0PeKmWN0KkENWfidGvHIcaRfP05tj2Oh1pA_UOm_iNTn8ioL1WgWjQ</recordid><startdate>20211231</startdate><enddate>20211231</enddate><creator>ÇALIŞKAN, Tezcan</creator><creator>YİLMAZ, Ibrahim</creator><creator>HACIOGLU, Fatma</creator><creator>ERSOZ, Emel</creator><creator>DOĞAN, Mustafa</creator><creator>KARAARSLAN, Numan</creator><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0002-5906-5859</orcidid><orcidid>https://orcid.org/0000-0003-2003-6337</orcidid><orcidid>https://orcid.org/0000-0001-7735-0584</orcidid><orcidid>https://orcid.org/0000-0002-3341-925X</orcidid><orcidid>https://orcid.org/0000-0002-3605-2350</orcidid><orcidid>https://orcid.org/0000-0001-5590-0637</orcidid></search><sort><creationdate>20211231</creationdate><title>The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses</title><author>ÇALIŞKAN, Tezcan ; YİLMAZ, Ibrahim ; HACIOGLU, Fatma ; ERSOZ, Emel ; DOĞAN, Mustafa ; KARAARSLAN, Numan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c856-db0d9d0d7fdfd10ef3ad24ff2a78ade731e750981bdeec1b9f2aefc33c6154203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ÇALIŞKAN, Tezcan</creatorcontrib><creatorcontrib>YİLMAZ, Ibrahim</creatorcontrib><creatorcontrib>HACIOGLU, Fatma</creatorcontrib><creatorcontrib>ERSOZ, Emel</creatorcontrib><creatorcontrib>DOĞAN, Mustafa</creatorcontrib><creatorcontrib>KARAARSLAN, Numan</creatorcontrib><collection>CrossRef</collection><jtitle>Acta medica Alanya</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ÇALIŞKAN, Tezcan</au><au>YİLMAZ, Ibrahim</au><au>HACIOGLU, Fatma</au><au>ERSOZ, Emel</au><au>DOĞAN, Mustafa</au><au>KARAARSLAN, Numan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses</atitle><jtitle>Acta medica Alanya</jtitle><date>2021-12-31</date><risdate>2021</risdate><volume>5</volume><issue>3</issue><spage>308</spage><epage>316</epage><pages>308-316</pages><issn>2587-0319</issn><eissn>2587-0319</eissn><abstract><![CDATA[Aim: The present study aims to examine the effectiveness of the neutrophil-to-lymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Method: In this retrospective study, radiological, neurological, and surgical data obtained from the medical records of healthy volunteers (n = 10) who presented to the hospital for check-ups and patients with brain abscesses who were treated (n = 10) were evaluated statistically. Alpha significance value was accepted as <0.05. Results: Comparisons between groups revealed that the erythrocyte sedimentation rate, C-reactive protein, leukocyte, and neutrophil values were statistically significant (P <0.05) while lymphocyte value was not statistically significant (P >0.05). The preoperative neutrophil-to-lymphocyte ratio in cases diagnosed with brain abscesses showed statistical significance compared to that in the healthy volunteers (P <0.05) and the neutrophil-to-lymphocyte ratio increased 3.31-fold in the study group compared to the healthy volunteers. Conclusion: A strong positive strong relationship between the neutrophil-to-lymphocyte ratio and abscess size (r = 0.662; P = 0.037) was observed. An increased neutrophil-to-lymphocyte ratio may serve as an early warning signal of brain abscesses. Keywords: Antibiotic treatment; brain abscess; low-cost diagnosis method; magnetic resonance image; neutrophil-to-lymphocyte ratio. Amaç: Bu makalede; beyin apsesi tanısı alan olgularda, nötrofil-lenfosit oranı (NLO)’nın, tanı ve tedavide önemli olup olmadığının incelenmesi amaçlandı. Metod: Retrospektif dizayna sahip araştırmada, hastaneye kontrol için gelen sağlıklı bireyler (n=10) ile beyin apsesi olan ve tedavi edilen olgular (n=10)’dan elde edilen radyolojik, nörolojik ve cerrahi veriler istatistiksel olarak değerlendirmeye alındı. Alfa anlamlılık değeri <0,05 olarak kabul edildi. Bulgular: Gruplar arası karşılaştırmalar sonucunda; eritrosit çökelme oranı (ESR), C-reaktif protein (CRP), lökosit (WBC) ve nötrofil (NEU) değerleri istatistiksel olarak anlamlı iken (P<0,05), lenfosit (LYMPH) değerinde istatistiksel olarak anlamlılık görülmedi (P>0,05). Sağlıklı bireylere oranla beyin apsesi tanısı alan olgulara ait preoperatif NLO değerlerinin istatistiksel olarak anlamlılık (P<0,05) gösterdiği ve NLO değerinin sağlıklı bireylere oranla yaklaşık 3,31 kat artış gösterdiği kaydedildi. Sonuç: NLO oranı ile abse boyutu arasında (r=0,662; P=0,037) pozitif yönde kuvvetli ilişki bulunmaktadır. Artış gösteren NLO, beyin apsesinin tanısında erken uyarı sinyali olarak hizmet edebilir.]]></abstract><doi>10.30565/medalanya.946066</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-5906-5859</orcidid><orcidid>https://orcid.org/0000-0003-2003-6337</orcidid><orcidid>https://orcid.org/0000-0001-7735-0584</orcidid><orcidid>https://orcid.org/0000-0002-3341-925X</orcidid><orcidid>https://orcid.org/0000-0002-3605-2350</orcidid><orcidid>https://orcid.org/0000-0001-5590-0637</orcidid><oa>free_for_read</oa></addata></record>
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title The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses
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