Measurement of granulocyte elastase and other parameters after operation for lung cancer
From April, 1990 to March, 1991, granulocyte elastase and other parameters were examined after operations for lung cancer. Four patients died, and nine survived. Five patients with pneumothorax served as controls. Leukocytes, granulocytes, granulocyte elastase, elastase/ granulocyte ratio, AT-III, T...
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| Veröffentlicht in: | Nihon Kokyuki Geka Gakkai zasshi (Kyoto, 1992) 1992/07/15, Vol.6(5), pp.562-567 |
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| container_title | Nihon Kokyuki Geka Gakkai zasshi (Kyoto, 1992) |
| container_volume | 6 |
| creator | Nanashima, Atsushi Itou, Shigehiko Ooe, Hisakuni Matsumoto, Yoshihiro Nakamura, Akihiro Yasutake, Tooru Soeda, Osamu Tsujino, Naoyuki |
| description | From April, 1990 to March, 1991, granulocyte elastase and other parameters were examined after operations for lung cancer. Four patients died, and nine survived. Five patients with pneumothorax served as controls. Leukocytes, granulocytes, granulocyte elastase, elastase/ granulocyte ratio, AT-III, TAT, α-PI and the respiratory index were measured on the day before operation and on the first, third and fifth days after operation. In the control group, granulocyte elastase remained within normal limits (21-165 μg/l). The survival group had transient increases of elastase on the day after operation, but normal levels by the fifthdays. In the patients who died, elastase levels were above 500 μg/l on the day after operation, and they continued to increase. High elastase levels cause a hypercoagulable state and respiratory disturbances. It is useful to predict DIC and respiratory complications after operations for lung cancer. |
| doi_str_mv | 10.2995/jacsurg.6.562 |
| format | Article |
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Four patients died, and nine survived. Five patients with pneumothorax served as controls. Leukocytes, granulocytes, granulocyte elastase, elastase/ granulocyte ratio, AT-III, TAT, α-PI and the respiratory index were measured on the day before operation and on the first, third and fifth days after operation. In the control group, granulocyte elastase remained within normal limits (21-165 μg/l). The survival group had transient increases of elastase on the day after operation, but normal levels by the fifthdays. In the patients who died, elastase levels were above 500 μg/l on the day after operation, and they continued to increase. High elastase levels cause a hypercoagulable state and respiratory disturbances. 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Four patients died, and nine survived. Five patients with pneumothorax served as controls. Leukocytes, granulocytes, granulocyte elastase, elastase/ granulocyte ratio, AT-III, TAT, α-PI and the respiratory index were measured on the day before operation and on the first, third and fifth days after operation. In the control group, granulocyte elastase remained within normal limits (21-165 μg/l). The survival group had transient increases of elastase on the day after operation, but normal levels by the fifthdays. In the patients who died, elastase levels were above 500 μg/l on the day after operation, and they continued to increase. High elastase levels cause a hypercoagulable state and respiratory disturbances. It is useful to predict DIC and respiratory complications after operations for lung cancer.</abstract><pub>The Japanese Association for Chest Surgery</pub><doi>10.2995/jacsurg.6.562</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| issn | 0919-0945 1881-4158 |
| language | eng |
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| subjects | disseminated intravascular coagulation granulocyte elastase postoperation for lung cancer respiratory disturbance |
| title | Measurement of granulocyte elastase and other parameters after operation for lung cancer |
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