223 Ra Induces Transient Functional Bone Marrow Toxicity

Ra is a bone-seeking, α-particle-emitting radionuclide approved for the treatment of patients with metastatic prostate cancer and is currently being tested in a variety of clinical trials for primary and metastatic cancers to bone. Clinical evaluation of Ra hematologic safety showed a significantly...

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Veröffentlicht in:	Journal of Nuclear Medicine 2022-10, Vol.63 (10), p.1544-1550
Hauptverfasser:	Parlani, Maria, Boccalatte, Francesco, Yeaton, Anna, Wang, Feng, Zhang, Jianhua, Aifantis, Iannis, Dondossola, Eleonora
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha Particles Bone and Bones Bone Marrow Flow Cytometry Humans Male Radioisotopes
Online-Zugang:	Volltext
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