18 F-Tetrafluoroborate, a PET Probe for Imaging Sodium/Iodide Symporter Expression: Whole-Body Biodistribution, Safety, and Radiation Dosimetry in Thyroid Cancer Patients

We report the safety, biodistribution, and internal radiation dosimetry, in humans with thyroid cancer, of F-tetrafluoroborate ( F-TFB), a novel PET radioligand for imaging the human sodium/iodide symporter (hNIS). Serial whole-body PET scans of 5 subjects with recently diagnosed thyroid cancer were...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Nuclear Medicine 2017-10, Vol.58 (10), p.1666-1671
Hauptverfasser:	O'Doherty, Jim, Jauregui-Osoro, Maite, Brothwood, Teresa, Szyszko, Teresa, Marsden, Paul K, O'Doherty, Michael J, Cook, Gary J R, Blower, Philip J, Lewington, Val
Format:	Artikel
Sprache:	eng
Schlagworte:	Borates - adverse effects Borates - metabolism Borates - pharmacokinetics Boric Acids - adverse effects Boric Acids - metabolism Boric Acids - pharmacokinetics Female Gene Expression Regulation, Neoplastic Humans Male Middle Aged Positron Emission Tomography Computed Tomography - methods Radiometry Safety Symporters - metabolism Thyroid Neoplasms - diagnostic imaging Thyroid Neoplasms - metabolism Tissue Distribution
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!