Biodistribution and Radiation Dosimetry for the Tau Tracer 18 F-THK-5351 in Healthy Human Subjects

F-THK-5351 is a novel radiotracer that demonstrates high binding selectivity and affinity for tau pathology and exhibits better pharmacokinetics in the living brain than previous THK tau probes. The aim of the present study was to estimate the radiation dose of F-THK-5351 in humans and to compare th...

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Veröffentlicht in:	Journal of Nuclear Medicine 2017-09, Vol.58 (9), p.1498-1503
Hauptverfasser:	Hsiao, Ing-Tsung, Lin, Kun-Ju, Huang, Kuo-Lun, Huang, Chin-Chang, Chen, Han-Shiuan, Wey, Shiaw-Pyng, Yen, Tzu-Chen, Okamura, Nobuyuki, Hsu, Jung-Lung
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aminopyridines - pharmacokinetics Female Healthy Volunteers Humans Male Middle Aged Positron-Emission Tomography Quinolines - pharmacokinetics Radioactive Tracers Radiometry Software tau Proteins - metabolism Tissue Distribution
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